Tetanus
Therapeutic area
Infectious Disease
Rare disease
Yes
- Definition
- A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Tetanus
- Therapeutic area
- Infectious Disease
- tetanus
- Clostridium tetani caused infectious disease of the nervous system
- Clostridium tetani infectious disease of the nervous system
- lockjaw
- Disease mechanisms
- Acquired
- Severity
- Severe
- Infectious Disease
- Neurology
- MONDO ID
- MONDO:0005526
- Parent condition
- MONDO:0000314
Related records
Broader conditions (13)
- Anaerobic bacteria infectious disease
- Bacterial infectious disease
- Clostridium infectious disease
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Gram-positive bacterial infections
- Human disease
- Infectious disease
- Infectious disorder of the nervous system
- Nervous system disorder
- Primary bacterial infectious disease
Narrower conditions (1)
- Tetanus neonatorum
Trials (300)
- 300 Antibody Diagnostic Test Kit
- A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine
- A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above)
- A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP)
- A Clinical Trial to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over
- A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component)
- A Combined Tdap Vaccine Used As A Booster Compared To Licensed Td Vaccine
- A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject
- A First in Human Study Investigating the Safety of an Unloaded and Loaded (With a Tetanus-containing Vaccine Booster) Microneedle Patch in Healthy Adults
- A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed
- A Phase 4 Study to Evaluate the Effectiveness and Safety of Siltartoxatug Injection for Tetanus Prophylaxis Following Injury
- A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents
- A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents)
- A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series
- A Phase Ⅲ Clinical Study of SNA02-48 Injection
- A Phase III Clinical Trail to Evaluate the Efficacy, Safety, Pharmacokinetics and Immunogenicity Characteristics of GR2001 Injection
- A Phase IV Study to Assess the Safety of EupentaTM Inj
- A Protocol to Collect Human Serum Samples From Healthy Adults for Use as Quality Controls Samples in GlaxoSmithKline (GSK) Biologicals' Assays
- A Randomized, Open-Label, Parallel-Design Pharmacokinetic and Pharmacodynamic Interaction Study of TNM002 and Adsorbed Tetanus Vaccine
- A Registry： Siltartoxatug Injection for Tetanus Prophylaxis Following Injury
Approved drugs (3)
Drugs in development (2)
- Pertussis vaccine Phase 3
- Siltartoxatug Phase 3
Other linked drugs (2)
- Bordetella pertussis filamentous hemagglutinin
- Bordetella pertussis pertactin autotransporter