> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/swine-influenza-a0f3b462-7878-5139-87b1-11e99944a1d8
> Record changed: 2026-10-13

# Swine influenza

Therapeutic area

Infectious Disease

Rare disease

No

## Definition and classification

**Definition**

An acute viral respiratory infection caused by a strain of influenza virus which is endemic in swine (pigs). Rarely reported in humans prior to 2009, the disease is caused by a mutated strain of swine influenza A (H1N1) virus. It is highly contagious and spreads mainly through coughing and sneezing. Signs and symptoms include fever, chills, coughing, sore throat headache, muscle ache, and generalized weakness. Antiviral medications are most effective in the first two days of the illness.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Swine influenza

**Therapeutic area**

Infectious Disease

### Alternative names (9)

- swine influenza
- H1N1 Influenza
- H1N1 Virus infection
- H1N1 flu
- Influenza A (H1N1)
- Influenza A (H1N1) Virus infection
- Swine influenza virus caused influenza
- Swine influenza virus influenza
- swine flu

## Clinical profile

**Disease mechanisms**

- Acquired

**Severity**

Severe

### All therapeutic areas (2)

- Infectious Disease
- Pulmonology

## Identifiers

**MONDO ID**

MONDO:0005460

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005460)

**Parent condition**

MONDO:0005812

## Related records

### Broader conditions (12)

- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- [Influenza](https://trialight.com/data/condition/influenza-ea12369b-7ed6-5f6b-94fe-eb0e56c24def.md)
- Primary viral infectious disease
- Respiratory system disorder
- [Respiratory tract infectious disorder](https://trialight.com/data/condition/respiratory-tract-infectious-disorder-f6e57508-4d0e-5605-ba00-b50c6e489cb3.md)
- [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md)
- Viral respiratory tract infection

### Trials (134)

- A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Adults
- A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Children
- A Multi-Site Clinical Evaluation of the LIAISON NES FLU A/B, RSV & COVID-19 Assay in Symptomatic Patients
- [A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A](https://trialight.com/data/trial/a-phase-2-study-to-evaluate-the-efficacy-and-safety-of-vir-0329e0e4-ef6b-4075-a4dc-53ac35f3ed60.md)
- A Phase I Study to Evaluate the Safety, Reactogenicity, and Humoral Immune Responses to an Inactivated H5N1 Influenza Vaccine
- A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA)
- A Pilot Study for Collection of Anti-Influenza A Immune Plasma
- A Prospective, Multicenter, Randomized Controlled Clinical Study on the Efficacy and Safety of Xuanfei Baidu Granule in the Treatment of Influenza A
- A Study of Different Formulations of an A/H1N1 Pandemic Vaccine in Healthy Adults and the Elderly
- A Study of Different Formulations of an A/H1N1 Pandemic Vaccine in Healthy Children Aged 6 Months to 9 Years
- A Study of Different Formulations of an Adjuvanted A/H1N1 Pandemic Vaccine in Healthy Adults and the Elderly
- A Study of Inactivated Swine-Origin A/H1N1 Influenza Vaccines in Healthy European Subjects Aged 3 to 17 Years
- A Study of MHAA4549A as Monotherapy for Acute Uncomplicated Seasonal Influenza A in Otherwise Healthy Adults
- A Study of Swine-origin A/H1N1 Influenza Vaccines in Healthy European Adults and the Elderly
- A Study of Swine-origin A/H1N1 Influenza Vaccines in Healthy Europeans Children Aged 6 to 35 Months
- A Study of the Immunogenicity of Swine-origin A/H1N1 Influenza Vaccine in Healthy Adults
- A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A
- A Study to Evaluate the Efficacy and Safety of CT-P27 in Acute Uncomplicated Influenza A Infection
- A Study to Evaluate the Efficacy and Safety of CT-P27 in an Influenza Challenge Model
- A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Hospitalized Participants With Influenza A Infection

### Drugs in development (5)

- Diridavumab Phase 2
- [Influenza virus vaccine](https://trialight.com/data/asset/influenza-virus-vaccine-99390506-afe0-4b83-a4c7-b7a43c41cb19.md) Phase 3
- [Rosuvastatin](https://trialight.com/data/asset/rosuvastatin-d8e48bc8-dc4d-4234-8b99-9b05b70b7a69.md) Phase 2
- SAB-176 Phase 2
- [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 2

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