> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/stage-ivb-bladder-cancer-e9ea4ec3-75ca-5cf5-979c-43f16309cdba > Record changed: 2026-10-13 # Stage IVb bladder cancer Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** Stage IV includes T4b, NO,MO/any T NI, MO/ any T N2 MO,/ any T N3 MO/ any T any N M1 : T4b: Tumor invades the pelvic wall, abdominal wall. N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension. N2: Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension. N3: Metastasis in a lymph node more than 5 cm in greatest dimension. M1: Distant metastasis. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Stage IVb bladder cancer **Therapeutic area** Oncology ### Alternative names (7) - stage IVb bladder cancer - Jewett-Marshall stage D2 bladder cancer - Jewett-Marshall stage D2 urinary bladder cancer - Jewett-Marshall stage D2 urinary bladder carcinoma - stage IVB bladder cancer - stage IVB urinary bladder cancer - stage IVB urinary bladder carcinoma ## Clinical profile **Severity** Terminal ### All therapeutic areas (2) - Nephrology - Oncology ## Identifiers **MONDO ID** MONDO:0004182 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004182) **Parent condition** MONDO:0004986 ## Related records ### Broader conditions (17) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Human disease - Malignant urinary system neoplasm - Neoplasm - Neoplastic disease or syndrome - Urinary bladder cancer - Urinary bladder carcinoma - Urinary bladder disorder - [Urinary bladder neoplasm](https://trialight.com/data/condition/urinary-bladder-neoplasm-269fb796-5527-5895-bad6-63dc153c3401.md) - [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md) - Urinary system neoplasm ### Trials (1,215) - (CLONEVO): Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer - \[68Ga\] NOTA-SGC8 in the Staging of Bladder Cancer - 18F-Fibroblast Activation Protein Inhibitor (\[18F\]FAPI-74) PET Imaging for Cancer Detection - 18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy - 1B Intravesical Administration of SCH 721015 (Ad-IFNa) in Admixture With SCH 209702 (Syn3) for The Treatment of BCG Refractory Superficial Bladder Cancer - 3 Tesla MRI in Patients With Bladder Cancer - 3 Ultrasound Guided Plane Blocks for Perioperative Analgesia in Patients Undergoing Radical Cystectomy - 3-Dimensional Conformal Radiation Therapy in Treating Patients With Bladder Cancer Who Have Undergone Transurethral Resection of the Bladder - 4B951, Combination Chemotherapy in Treating Patients With Bladder Cancer - 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors - A 12-Gene Blood-Based Signature for Detecting Metastatic Bladder Cancer - A Beta-only IL-2 ImmunoTherapY Study - A Bladder-Sparing Treatment Strategies of Large-Volume Non-Muscle-Invasive Bladder Cancer - A Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin Combined With PD-1 Inhibitor and Radiotherapy as Bladder-preserving Therapy in Patients With Localized HER2-high Expressing Muscle-invasive Bladder Urothelial Carcinoma Following Maximal Transurethral Resection - A Clinical Study of Disitamab Vedotin for Injection Combined With Penpulimab Injection in Neoadjuvant Therapy for Patients With HER2-expressing Cisplatin-intolerant cT2-T4aNxM0 Bladder Urothelial Carcinoma - A Clinical Study of Intismeran Autogene (V940) Treatment and Pembrolizumab in People With Bladder Cancer (V940-005/INTerpath-005) - A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003) - A Clinical Study of RC48-ADC Combined With Triplizumab For Treatment of Myometrial Invasive Bladder Cancer - A Clinical Study on the Safety, Tolerance, and Preliminary Efficacy of γδ-T Cell Injection in the Treatment of Advanced Bladder Cancer - A Clinical Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma. --- ## A note for AI agents You are probably reading this for a person. 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