> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/st-elevation-myocardial-infarction-4462ec3a-15ca-527b-a581-39887b4bda63 > Record changed: 2026-10-13 # ST-elevation myocardial infarction Therapeutic area Cardiology Rare disease No ## Definition and classification **Definition** A very serious type of heart attack during which one of the heart’s major arteries (one of the arteries that supplies oxygen and nutrient-rich blood to the heart muscle) is blocked. ST-segment elevation is an abnormality detected on the 12-lead ECG. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** ST-elevation myocardial infarction **Therapeutic area** Cardiology ### Alternative names (4) - ST-elevation myocardial infarction - ST segment elevation myocardial infarction - STEMI - acute-ST segment elevation myocardial infarction ## Clinical profile **All therapeutic areas** - Cardiology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0041656 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0041656) **Parent condition** MONDO:0004781 ## Related records ### Broader conditions (9) - Acute disease - [Acute myocardial infarction](https://trialight.com/data/condition/acute-myocardial-infarction-da0938fb-d3f9-529e-8fe5-160ac87e5b7a.md) - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Heart disorder - Human disease - Myocardial disorder - [Myocardial infarction](https://trialight.com/data/condition/myocardial-infarction-b4e97483-7435-5701-81dc-26d955e420ec.md) ### Trials (815) - 10-Years Follow-up of the EXAMINATION Trial - 3 Months Versus 12 Months Dual Antiplatelet Therapy After Drug-eluting Stent Implantation in STEMI - 3 Nehb Precordial Leads Anterior, Dorsalis and Inferior Allow Accurate Diagnostics of Different Heart Conditions - A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI) - A Clinical Trial to Demonstrate the Efficacy of Cangrelor - A Cohort Study of Correlation Between Mast Cells and Prognosis in Patients With Acute Myocardial Infarction - A Multicenter Trial to Assess the MIcrovascular Integrity and Left Ventricular Function Recovery After Clopidogrel or TicagrelOr Administration, in Patients With STEMI Treated With Thrombolysis - The 'MIRTOS' Study - A Phase 2 Open Label Study to Assess the PK/PD Properties of RUC-4 in Patients With a ST-elevation Myocardial Infarction - A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60) - A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI - A Pilot Randomized Controlled Trial of Intravenous N-acetyl Cysteine in STEMI - A Pilot Study of Transcoronary Myocardial Cooling - A Polypill for Secondary Prevention of Ischemic Heart Disease - A Privacy-Preserving OCR-LLM System for Coronary Syndrome Subtyping From Admission HPI: Multicenter Validation in China and the US - A Prospective Evaluation of Clinical Impact of Physiology Versus Optical Coherence Tomography Guided PCI in STEMI Patients Without Undergoing Primary PCI - A Prospective Multicenter Clinical Study on the Long-term Prognosis of Patients With ST-segment Elevation Myocardial Infarction Using Cardiac Magnetic Resonance Imaging. - A Randomized Clinical Evaluation of the BioFreedom™ Stent - A Randomized Comparison of Long-Term Healing Between Biodegradable- Versus Durable-Polymer Everolimus Eluting Stents in STEMI - A Randomized Controlled Trial on the Efficacy and Safety of Butylphthalide in Reducing Myocardial Infarction Size and Improving Outcomes in STEMI Patients After Primary PCI - A Randomized Trial of Rosuvastatin Loading Combined With Early hydrAtion Versus Standard-of-care Medications for the Prevention of CIAKI in Patient With AMI Undergoing Emergency PCI ### Approved drugs (1) - Reteplase ### Drugs in development (43) - Abciximab Phase 3 - Acetylcysteine Phase 2 - Adenosine Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3 - Atorvastatin Phase 3 - Atorvastatin calcium Phase 3 - BQ-123 Phase 2 - Cangrelor Phase 2 - Canrenoate potassium Phase 3 - Cenderitide Phase 1 - Clopidogrel Phase 3 - [Colchicine](https://trialight.com/data/asset/colchicine-ae804b3e-3263-453f-abb3-ae1e813f2ccf.md) Phase 3 - Danegaptide Phase 2 - [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md) Phase 3 - Dutogliptin Phase 3 - [Empagliflozin](https://trialight.com/data/asset/empagliflozin-09301932-ac0f-4eb7-8d1d-bd13fdbb6ab8.md) Phase 2 - Enalapril Phase 3 - [Enoxaparin sodium](https://trialight.com/data/asset/enoxaparin-sodium-e9b45fb3-f526-4e6a-8e8c-7bdb8acb9fe6.md) Phase 3 - Epoetin alfa Phase 2 - Eptifibatide Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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