> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/soft-tissue-sarcoma-3abd95b0-f8eb-5f0b-9e18-b37874e7f988 > Record changed: 2026-10-13 # Soft tissue sarcoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Soft tissue sarcoma **Therapeutic area** Oncology ### Alternative names (11) - soft tissue sarcoma - malignant soft tissue tumor - malignant soft tissue tumour - connective tissue sarcoma - malignant mesenchymal tumor - malignant mesenchymal tumour - non-Rhabdo. soft tissue sarcoma - sarcoma of soft tissue - sarcoma of the soft tissue - soft part sarcoma - soft tissue sarcoma ## Clinical profile **All therapeutic areas** - Oncology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0018078 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0018078) **Parent condition** MONDO:0005089 ## Related records ### Broader conditions (11) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Connective and soft tissue neoplasm - Disease - Disease by etiologic mechanism - Human disease - Malignant soft tissue neoplasm - Neoplasm - Neoplastic disease or syndrome - [Sarcoma](https://trialight.com/data/condition/sarcoma-96102668-50d9-5d69-b154-719396a38dc1.md) - Soft tissue neoplasm ### Narrower conditions (245) - Adult botryoid rhabdomyosarcoma - Adult epithelioid sarcoma - Adult extraskeletal osteosarcoma - Adult fibrosarcoma - Adult liposarcoma - Adult malignant schwannoma - Adult pleomorphic rhabdomyosarcoma - Adult vagina botryoid embryonal rhabdomyosarcoma - Alveolar rhabdomyosarcoma - Alveolar soft part sarcoma - Anaplastic sarcoma of the kidney - Angiosarcoma - Angiosarcoma of the scalp - Anus leiomyosarcoma - Anus rhabdomyosarcoma - Anus sarcoma - Aorta angiosarcoma - Atypical teratoid rhabdoid tumor - Atypical teratoid rhabdoid tumor, MYC-activated - Atypical teratoid rhabdoid tumor, SHH-activated ### Trials (548) - "Exercise Intervention to Increase Physical Activity in Young Sarcoma Survivors (Sport Ist Herzenssache)" - (SBRT) and (ART) for Pulmonary Metastases From Soft Tissue Sarcomas - 5-AminoLevulinic Acid Aided Resection Margins in Sarcoma - 5-Day Preoperative Radiation for Soft Tissue Sarcoma - 68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas - 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors - 89Zr-olaratumab Dosimetry in Participants With PDGFR Alpha Positive Solid Tumours and Soft Tissue Sarcoma - A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue Sarcoma - A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors - A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue Tumors - A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma - A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors - A Clinical Trial to Evaluate the Efficacy and Safety of Anotinib Hydrochloride Capsule Combined With Epirubicin Hydrochloride Versus Placebo Combined With Epirubicin Hydrochloride in First-line Treatment of Advanced Soft Tissue Sarcoma - A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma - A Japanese Trial of TH-302 in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma - a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4 - A Multicenter, Prospective, oBservational Study to assEss the Clinical activitY and Impact on symptOm Burden and patieNts' HRQoL of Treatment With trabecteDin in aSTS in a Real World Setting in Greece - A Multicenter, Single-arm, Prospective Phase II Clinical Study of Epalrotokewali Combined With Eribulin, Anlotinib, and Radiotherapy for the Treatment of Patients With Advanced Soft Tissue Sarcoma. - A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors - A Phase 1B Dose-escalation and Phase 2a Study of Carotuximab (TRC105) in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma ### Approved drugs (4) - [Doxorubicin hydrochloride](https://trialight.com/data/asset/doxorubicin-hydrochloride-2e3493ba-9766-475e-aa7d-f2debf111de5.md) - Olaratumab - Pazopanib hydrochloride - Trabectedin ### Drugs in development (129) - \[18F\]FLUOROMISONIDAZOLE Phase 1 - Afamitresgene autoleucel Phase 2 - [Albumin human](https://trialight.com/data/asset/albumin-human-95414b67-0d38-49d4-91b2-27b1c6c17389.md) Phase 1 - Aldoxorubicin Phase 3 - Aminolevulinic acid Phase 1 - Amrubicin Phase 2 - Antineoplaston A10 Phase 2 - Ascorbic acid Phase 1 - Axitinib Phase 2 - Balstilimab Phase 2 - Belinostat Phase 1 - [Bendamustine](https://trialight.com/data/asset/bendamustine-07f7a21f-820a-4423-a534-0d6d0380b382.md) Phase 2 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - Bintrafusp alfa Phase 2 - Bupivacaine Early phase 1 - [Cabozantinib](https://trialight.com/data/asset/cabozantinib-e69f9fa7-bbbc-4e52-b0df-6073598de2a7.md) Phase 2 - Cabozantinib S-malate Phase 1 - [Cadonilimab](https://trialight.com/data/asset/cadonilimab-3970701f-ffc8-4027-a97b-4e6c913803e6.md) Phase 2 - Camrelizumab Phase 2 - Camsirubicin Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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