> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/skin-squamous-cell-carcinoma-29047668-8486-533e-ac8b-779eed01f018 > Record changed: 2026-10-13 # Skin squamous cell carcinoma Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** A carcinoma arising from the squamous cells of the epidermis. Skin squamous cell carcinoma is most commonly found on sun-exposed areas. The majority of the tumors are well-differentiated. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Skin squamous cell carcinoma **Therapeutic area** Oncology ### Alternative names (13) - skin squamous cell carcinoma - cutaneous squamous cell carcinoma - epidermoid carcinoma of skin - epidermoid carcinoma of the skin - epidermoid skin carcinoma - skin squamous cell cancer - skin squamous cell carcinoma - squamous cell carcinoma - skin - squamous cell carcinoma of skin - squamous cell carcinoma of the skin - squamous cell skin carcinoma - zone of skin squamous cell carcinoma - CSCC ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Dermatology - Oncology ## Identifiers **MONDO ID** MONDO:0002529 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002529) **Parent condition** MONDO:0002656 ## Related records ### Broader conditions (19) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Epithelial skin neoplasm - Human disease - Integumentary system cancer - Integumentary system disorder - Neoplasm - Neoplastic disease or syndrome - [Skin cancer](https://trialight.com/data/condition/skin-cancer-562f3839-7ec8-5b32-b9c3-764f924d64d8.md) - Skin carcinoma - [Skin disorder](https://trialight.com/data/condition/skin-disorder-c8e27943-0efd-5c2b-abce-01c2ef37e853.md) - [Skin neoplasm](https://trialight.com/data/condition/skin-neoplasm-b16c2929-b23f-5a5d-a969-c98d7c3350ea.md) - [Squamous cell carcinoma](https://trialight.com/data/condition/squamous-cell-carcinoma-44944de3-3c1f-5714-9da2-a28db7d896c2.md) - Squamous cell neoplasm ### Narrower conditions (10) - Acantholytic squamous cell skin carcinoma - Anal margin squamous cell carcinoma - Bowen disease of the skin - Clear cell squamous cell skin carcinoma - Plantar verrucous skin carcinoma - Pseudovascular skin squamous cell carcinoma - Sarcomatoid squamous cell skin carcinoma - Skin adenosquamous carcinoma - Skin basaloid carcinoma - Skin squamous cell carcinoma in situ ### Trials (176) - A Beta-only IL-2 ImmunoTherapY Study - A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid Tumors - A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized, Locally Recurrent, or Regionally Advanced Skin Cancer - A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision - [A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers](https://trialight.com/data/trial/a-phase-ib-ii-study-of-an-anti-her3-antibody-hmbd-001-with-026a36f4-4a47-44e5-942f-01f081708ee9.md) - A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients - A Study of IDP-001 in Advanced or Metastatic Solid Tumors - A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer - A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer - A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201) - A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors - A Study of Tolododekin Alfa (ANK-101) in Renal Allograft Recipients With High Risk Cutaneous Squamous Cell Carcinoma - A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors - A Study of VET3-TGI in Patients With Solid Tumors - A Study to Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma - A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer - A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors - ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTS - Alpha Radiation Emitters Device for the Treatment of Squamous Cell Carcinoma (DaRT) - An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors ### Drugs in development (1) - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 2 ### Other linked drugs (1) - [Paclitaxel](https://trialight.com/data/asset/paclitaxel-889db92c-df97-46a6-bf1c-74974a87fa75.md) --- ## A note for AI agents You are probably reading this for a person. 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