> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/severe-acute-respiratory-syndrome-7654d02a-f750-52a0-bec2-afe3b4b3c224
> Record changed: 2026-10-13

# Severe acute respiratory syndrome

Therapeutic area

Pulmonology

Rare disease

Yes

## Definition and classification

**Definition**

A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Severe acute respiratory syndrome

**Therapeutic area**

Pulmonology

### Alternative names (6)

- severe acute respiratory syndrome
- SARS
- SARS coronavirus caused disease or disorder
- SARS coronavirus disease or disorder
- SARS coronavirus infectious disease
- acute respiratory coronavirus infection

## Clinical profile

**Disease mechanisms**

- Acquired

**Severity**

Severe

### All therapeutic areas (2)

- Infectious Disease
- Pulmonology

## Identifiers

**MONDO ID**

MONDO:0005091

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005091)

**Parent condition**

MONDO:0005087

## Related records

### Broader conditions (13)

- Acute disease
- [Coronaviridae infectious disease](https://trialight.com/data/condition/coronaviridae-infectious-disease-a8965375-a1fc-5dd2-8630-45f68ede603b.md)
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- [Nidovirales infectious disease](https://trialight.com/data/condition/nidovirales-infectious-disease-c9461f21-7e20-543c-b62a-3a0fdf17b800.md)
- Orthocoronavirinae infectious disease
- Primary viral infectious disease
- Respiratory system disorder
- [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md)

### Trials (363)

- '4C' Intervention to Reduce SARS-CoV-2 (Covid-19) Transmission
- A Clinical Evaluation of Pine Trees Health Test System Including the Pine Trees Health Reader and COVID-19 Test for Point-of-Care
- A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
- A Feasibility Study Using the CoronaCheck Device to Identify Incident Cases of SARS CoV-2 Covid-19
- A Longitudinal Study of COVID-19 Positive Patients Testing Nasal Swabs and Collecting Blood Samples for Research
- A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome
- A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19
- A Phase III Clinical Trial of the Immunogenicity and Safety of the Gam-COVID-Vac Vaccine Against COVID-19 in the UAE
- A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic
- A Registry Study of COVID-19 Serologic and Virologic Testing to Accelerate Recovery and Transition
- A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19
- A Study of LY3127804 in Participants With COVID-19
- A Study to Assess Pulsed Inhaled Nitric Oxide vs Placebo in Subjects With Mild or Moderate COVID-19
- A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)
- A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2
- A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19
- A Study To Evaluate The Performance of the Lucira Health All-In-One COVID-19 Test Kit vs Hologic Panther Fusion
- A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19
- A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
- A Systems Approach to Predict the Outcome of SARS-CoV-2 in the Population of a City; COVID-19

### Approved drugs (5)

- [Elasomeran](https://trialight.com/data/asset/elasomeran-7d917cbd-1f45-43e8-a188-fd6dec78e983.md)
- Remdesivir
- [Sotrovimab](https://trialight.com/data/asset/sotrovimab-0c8591ea-4fda-4507-a997-becf3e6a8690.md)
- [Tocilizumab](https://trialight.com/data/asset/tocilizumab-58fcf741-84ea-43ec-ab1b-8fc8d306b59d.md)
- [Tozinameran](https://trialight.com/data/asset/tozinameran-bb0e4f65-bf06-4152-bd75-c7c1f5505a9d.md)

### Drugs in development (102)

- [Alteplase](https://trialight.com/data/asset/alteplase-89461f67-4f40-4a00-ae4c-727752018887.md) Phase 2
- [Aluminum hydroxide](https://trialight.com/data/asset/aluminum-hydroxide-a0230a1f-a5e2-439f-baa2-2b988b59e46d.md) Phase 1
- [Anakinra](https://trialight.com/data/asset/anakinra-2c0352ee-cb20-46c5-bd87-6350d9024e75.md) Phase 3
- Ascorbic acid Phase 3
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3
- Azilsartan Phase 3
- Azithromycin Phase 3
- [Baloxavir marboxil](https://trialight.com/data/asset/baloxavir-marboxil-95bb0047-8ebb-4242-af68-67848f77b384.md) Phase 3
- [Baricitinib](https://trialight.com/data/asset/baricitinib-dde0cdc5-8f75-41b1-bc92-b187471c63df.md) Phase 3
- [Bemnifosbuvir](https://trialight.com/data/asset/bemnifosbuvir-2801e1d5-93ea-48b5-a5b6-91d5bb0db82e.md) Phase 3
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 3
- Bicalutamide Phase 3
- [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md) Phase 3
- Camostat Phase 3
- Camostat mesilate Phase 3
- Candesartan Phase 3
- Cannabinol Phase 2
- Casirivimab Phase 3
- Chloroquine phosphate Phase 2
- [Cholecalciferol](https://trialight.com/data/asset/cholecalciferol-c9dc6a9a-8bc7-4070-a34e-535013073648.md) Phase 3

---

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