> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/rheumatic-disorder-e863530e-2c28-5a33-b1be-d12fa4d746b9
> Record changed: 2026-10-13

# Rheumatic disorder

Therapeutic area

Rheumatology

Rare disease

No

## Definition and classification

**Definition**

Inflammatory and degenerative diseases of connective tissue structures, such as arthritis.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Rheumatic disorder

**Therapeutic area**

Rheumatology

### Alternative names (8)

- rheumatic disorder
- rheumatic disease
- rheumatologic disorder
- disease, rheumatic
- diseases, rheumatic
- enthesopathies
- enthesopathy
- rheumatism

## Clinical profile

**All therapeutic areas**

- Rheumatology

**Severity**

Moderate

## Identifiers

**MONDO ID**

MONDO:0005554

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005554)

**Parent condition**

MONDO:0003900

## Related records

### Broader conditions (4)

- [Connective tissue disorder](https://trialight.com/data/condition/connective-tissue-disorder-3df54ecd-c080-5b4c-b60d-fab4846ea17b.md)
- Disease
- Disease by body system or component
- Human disease

### Narrower conditions (227)

- Acroosteolysis dominant type
- ADAR-related type 1 interferonopathy
- Adermatopathic dermatomyositis
- Adult dermatomyositis
- Adult-onset Still disease
- Aicardi-Goutieres syndrome
- Aicardi-Goutieres syndrome 1
- Aicardi-Goutieres syndrome 2
- Aicardi-Goutieres syndrome 3
- Aicardi-Goutieres syndrome 4
- Aicardi-Goutieres syndrome 5
- Aicardi-Goutieres syndrome 6
- Aicardi-Goutieres syndrome 7
- Aicardi-Goutieres syndrome 8
- Aicardi-Goutieres syndrome 9
- Al Gazali Khidr Prem Chandran syndrome
- Amyopathic dermatomyositis
- [Ankylosing spondylitis](https://trialight.com/data/condition/ankylosing-spondylitis-9b1fe73f-f462-5baf-85b0-5cbf33725458.md)
- Anti-MDA5 dermatomyositis
- Anti-Mi2 dermatomyositis

### Trials (274)

- 41.8 Degree Centigrade Whole Body Hyperthermia for the Treatment of Rheumatoid Diseases
- A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica
- A Clinical Study to Map the HLA Genomic Region in the Greek Population
- A Comparison of Patients Receiving a Total Knee Replacement With Robotic Assistance or With Conventional Instrumentation
- A Comparison of Patients Receiving a Unicompartmental Knee Replacement With Robotic Assistance or With Conventional Instrumentation
- A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome
- A Phase 2a Study Evaluating the Safety and Efficacy of ABT-981 in Patients With Erosive Hand Osteoarthritis
- A Phase III Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of Plonmarlimab in Subjects With Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis (Also Known as Macrophage Activation Syndrome \[MAS\])
- A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee Marching On for Veterans With Osteoarthritis of the Knee
- A Registry Study of Sanwujiaowan Capsule Used in Clinical Real World
- A Soft Robotics Approach Towards Finger Joint Deformities in Rheumatic Diseases
- A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee
- A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 12 Weeks in Adults With Active Primary Sjögren's Syndrome (pSS)
- A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate
- A Study of IN026 in Participants With Refractory Gout
- [A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis](https://trialight.com/data/trial/a-study-of-peresolimab-ly3462817-in-participants-with-0dbaefe8-15e1-45f3-962f-1647df769ef8.md)
- A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
- A Study of Single and Multiple Ascending Doses of VIB1116 in Rheumatic Diseases
- A Study of SPY072 in Rheumatic Disease
- A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets

### Approved drugs (54)

- Aceclofenac
- Acemetacin
- Alclofenac
- Apazone
- Auranofin
- Benoxaprofen
- Benzydamine
- Bufexamac
- Captopril
- [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md)
- Dexibuprofen
- Dexketoprofen
- Diacerein
- [Diclofenac](https://trialight.com/data/asset/diclofenac-6bb6f2bf-7068-41cb-8e1d-c1c073cf27b3.md)
- Etodolac
- Etoricoxib
- Fenbufen
- Fenoprofen
- Feprazone
- Flufenamic acid

### Drugs in development (27)

- Alminoprofen Phase 2
- Bucillamine Phase 3
- Bumadizone Phase 2
- Chondroitin sulfate sodium Phase 3
- Clofezone Phase 2
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 1
- Droxicam Phase 2
- Fentiazac Phase 2
- Flunoxaprofen Phase 2
- Hydroxychloroquine sulfate Phase 1
- Ibuproxam Phase 2
- Kebuzone Phase 2
- Lonazolac Phase 2
- Mofebutazone Phase 2
- Morniflumate Phase 2
- Morphine Phase 1
- Naproxcinod Phase 3
- Niflumic acid Phase 2
- Oxaceprol Phase 2
- Oxametacin Phase 2

### Other linked drugs (2)

- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md)
- Tramadol

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