> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/renal-cell-carcinoma-31bf4f99-9824-5c93-9472-9f4da019c25c > Record changed: 2026-10-13 # Renal cell carcinoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A carcinoma that arises from glandular epithelial cells of the kidney **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Renal cell carcinoma **Therapeutic area** Oncology ### Alternative names (6) - renal cell carcinoma - RCC - renal cell carcinoma - renal cell carcinoma (disease) - kidney adenocarcinoma - renal cell adenocarcinoma ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Nephrology - Oncology ## Identifiers **MONDO ID** MONDO:0005086 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005086) **Parent condition** MONDO:0004970 ## Related records ### Broader conditions (19) - [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Glandular cell neoplasm - Human disease - Kidney cancer - [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md) - [Kidney neoplasm](https://trialight.com/data/condition/kidney-neoplasm-6261fea0-4c11-5866-946d-1bb40d83f6e3.md) - Malignant urinary system neoplasm - Neoplasm - Neoplastic disease or syndrome - [Renal carcinoma](https://trialight.com/data/condition/renal-carcinoma-133a40e2-e2f7-5921-9086-8e1e5b29f34d.md) - [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md) - Urinary system neoplasm ### Narrower conditions (36) - Acquired cystic disease-associated renal cell carcinoma - Adrenal cortex carcinoma - Adrenocortical carcinoma, hereditary - Aniridia 2 - Aniridia 3 - Childhood kidney cell carcinoma - Childhood renal cell carcinoma with MiT translocations - Chromophobe renal cell carcinoma - Classic variant of chromophobe renal cell carcinoma - Clear cell papillary renal cell carcinoma - [Clear cell renal carcinoma](https://trialight.com/data/condition/clear-cell-renal-carcinoma-789eee25-ec64-5771-9b7d-d19544781b11.md) - Collecting duct carcinoma - Cystic renal cell carcinoma - Eosinophilic variant of chromophobe renal cell carcinoma - Foveal hypoplasia 1 - Hereditary clear cell renal cell carcinoma - Hereditary papillary renal cell carcinoma - Hereditary renal cell carcinoma - Isolated optic nerve hypoplasia - Kidney medullary carcinoma ### Trials (1,985) - "Embolization Before Ablation of Renal Cell Carcinoma (EMBARC)" - "Retrospective Study to Identify Clinical Factors Related to a High Benefit of Axitinib in mRCC" - \[18\]F-FAZA PET Imaging Study in Patients With Cancer of the Head & Neck, Lung, Renal Cell, Brain, Lymphoma and Neuroendocrine Tumours - \[18F\]PT2385 PET/CT in Patients With Renal Cell Carcinoma - 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic Kidney Cancer - 177LuPSMA in Renal Cell Carcinoma - 17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease - 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases - 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy - 18F-FSPG PET/CT for Cancer Patients on Therapy - 18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors - 1st-line Activity of Dovitinib and Correlation With Genetic Changes in RCC - 3-AP in Treating Patients With Previously Untreated Locally Recurrent or Metastatic Renal Cell Carcinoma - 3D-biomodels for Surgical Planning in Patients With Renal Cancer and Vascular Involvement - 6-Hydroxymethylacylfulvene in Treating Patients With Metastatic Kidney Cancer - 68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma - 68Ga-labeled NY104 PET Imaging in Patients - 68Ga-NY104 PET/CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses - 68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC. - 68Ga-NY104 PET/CT Imaging in Renal Cell Carcinoma ### Approved drugs (16) - Axitinib - [Belzutifan](https://trialight.com/data/asset/belzutifan-2287c89c-8beb-4a1c-a6de-f8d6dfb3499b.md) - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) - Cabozantinib S-malate - [Everolimus](https://trialight.com/data/asset/everolimus-0edf09a9-672d-4f9a-9e34-21ab083a92a4.md) - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) - Lenvatinib mesylate - [Medroxyprogesterone acetate](https://trialight.com/data/asset/medroxyprogesterone-acetate-5514a525-6952-4a47-8871-8a2425a74366.md) - [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md) - Pazopanib hydrochloride - [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md) - Sorafenib tosylate - Sunitinib - Sunitinib malate - Temsirolimus - Tivozanib hydrochloride ### Drugs in development (196) - Abexinostat Phase 3 - ABT-510 Phase 2 - ABT-751 Phase 2 - Afeletecan hydrochloride Phase 2 - [Aflibercept](https://trialight.com/data/asset/aflibercept-6bb09e87-ca99-436b-8634-71b90510b8fb.md) Phase 2 - Agatolimod sodium Phase 1 - AGS-16C3F Phase 2 - Aldesleukin Phase 3 - Amcasertib Phase 2 - Apitolisib Phase 2 - Archexin Phase 1 - AS-1409 Phase 1 - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 3 - ATN-161 Phase 2 - Atorvastatin Phase 2 - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 3 - [Azacitidine](https://trialight.com/data/asset/azacitidine-4f3798ea-680c-4288-a367-118b7bfe411f.md) Phase 1 - Balstilimab Phase 2 - Bempegaldesleukin Phase 3 - Bexmarilimab Phase 1 ### Other linked drugs (10) - Bicalutamide - CDX-014 - Coagulation factor X human - Ieramilimab - Ketorolac tromethamine - Mavorixafor - Pafolacianine - Sifalimumab - Tucidinostat - Zenocutuzumab --- ## A note for AI agents You are probably reading this for a person. 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