> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/rectal-neoplasm-90ce6f8e-1e92-5fe7-aa15-a594440faf2c > Record changed: 2026-10-13 # Rectal neoplasm Therapeutic area Gastroenterology Rare disease No ## Definition and classification **Definition** A benign or malignant neoplasm that affects the rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Rectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Rectal neoplasm **Therapeutic area** Gastroenterology ### Alternative names (13) - rectal neoplasm - neoplasm of rectum - neoplasm of the rectum - rectal neoplasm - rectal tumor - rectal tumour - rectum neoplasm (disease) - rectum tumor - rectum tumour - tumor of rectum - tumor of the rectum - tumour of rectum - tumour of the rectum ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Gastroenterology - Oncology ## Identifiers **MONDO ID** MONDO:0002165 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002165) **Parent condition** MONDO:0001593 ## Related records ### Broader conditions (14) - Cancer or benign tumor - [Colorectal neoplasm](https://trialight.com/data/condition/colorectal-neoplasm-31f0a633-3abe-5df4-9d3a-9292c6541f1d.md) - [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md) - [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - Intestinal disorder - Intestinal neoplasm - Large intestine disorder - Neoplasm - Neoplastic disease or syndrome - Rectal disorder ### Narrower conditions (62) - Anal canal adenocarcinoma - Anal canal carcinoma - Anal canal carcinoma in situ - Anal canal neuroendocrine neoplasm - Anal canal Paget disease - Anal canal squamous cell carcinoma - [Anal carcinoma](https://trialight.com/data/condition/anal-carcinoma-d0dca5aa-14ee-5bcc-8bd1-2a2539daa2ec.md) - Anal gland adenocarcinoma - Anal gland neoplasm - Anal margin basal cell carcinoma - Anal margin carcinoma - Anal margin squamous cell carcinoma - Anal melanoma - Anal mucinous adenocarcinoma - Anal Paget disease - Anal squamous cell carcinoma - Anal verrucous carcinoma - Anus adenocarcinoma - Anus basaloid carcinoma - Anus cancer ### Trials (2,222) - "Cross" Closure for Reconstructing the Perineal Wound of Abdominoperineal Resection - "Impact of Pelvic Floor Prehabilitation Using Biofeedback on the Severity of the Low Anterior Resection Syndrome in Patients Undergoing a Total Mesorectal Excision for Rectal Cancer" - "Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study". - "Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer - "Watch and Wait" After Neo-adjuvant Chemoradiotherapy for Primary Locally Advanced Rectal Cancer. - \[F-18\] Fluorothymidine PET/CT Imaging for Pelvic Cancers - 1. SAFE-AI ONCO-TRACK: Multimodal GenAI for Early Detection of Minimal Residual Disease and Recurrence in Gastrointestinal Oncology - 16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer - 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy - 1st Line Chemotherapy Alone or With Bevacizumab in Treating Older Patients With Metastatic Colorectal Cancer - 2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer - 35kDa Hyaluronan Fragment Treatment of Colorectal and Rectal Cancer - 3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin - 5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer - 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer - 5FU/VL Vs LV5FU2 + CPT11 in Stage II-III Resected Rectal Cancer - 64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum) - 68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy - 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) - A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients ### Drugs in development (3) - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 3 - [Dostarlimab](https://trialight.com/data/asset/dostarlimab-aad06b17-e988-4591-813f-4b6cef63860f.md) Phase 2 - Irinotecan Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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