Pulmonary hypertension
Therapeutic area
Vascular Medicine
Rare disease
No
- Definition
- Increased pressure within the pulmonary circulation due to lung or heart disorder.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Pulmonary hypertension
- Alternative names
- pulmonary hypertension
- Therapeutic area
- Vascular Medicine
- Severity
- Severe
- Cardiology
- Vascular Medicine
- MONDO ID
- MONDO:0005149
- Parent condition
- MONDO:0005044
Related records
Broader conditions (7)
- Arterial disorder
- Cardiovascular disorder
- Disease
- Disease by body system or component
- Human disease
- Hypertensive disorder
- Vascular disorder
Narrower conditions (18)
- Braddock syndrome
- Chronic thromboembolic pulmonary hypertension
- Drug- or toxin-induced pulmonary arterial hypertension
- Eisenmenger syndrome
- Heritable pulmonary arterial hypertension
- Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome
- Idiopathic pulmonary arterial hypertension
- Pulmonary arterial hypertension
- Pulmonary hypertension owing to lung disease and/or hypoxia
- Pulmonary hypertension, neonatal
- Pulmonary hypertension, primary, 1
- Pulmonary hypertension, primary, 2
- Pulmonary hypertension, primary, 3
- Pulmonary hypertension, primary, 4
- Pulmonary hypertension, primary, 5
- Pulmonary hypertension, primary, 6
- Pulmonary hypertension, primary, 7
- Pulmonary veno-occlusive disease and/or pulmonary capillary haemangiomatosis
Trials (996)
- [18F]FES PET/CT in PAH
- 11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension
- 129 Xenon Imaging in Patients Treated With Sotatercept
- 3 Part Study to Assess Inhaled Nitric Oxide on Functional Pulmonary Imaging in Subj. Pulmonary Hypertension Associated w/ COPD and IPF
- 4D-flow Cardiac MRI to Assess Pulmonary Arterial Pressure in Pulmonary Hypertension
- A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients
- A 48-week Study of the Effect of Dual Therapy (Inhaled Treprostinil and Tadafafil) Versus Monotherapy (Tadalafil).
- A Case Control Study of the Prevalence of Pulmonary Hypertension in Patients With Myeloproliferative Diseases.
- A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
- A Comparative Study of Three Modes of Ventilation During CPB in Pediatrics With Pulmonary Hypertension Undergoing Congenital Heart Surgeries
- A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects on Oral Medications for the Treatment of Interstitial Lung Disease, Sarcoid and Pulmonary Hypertension
- A Deep-Learning-Enabled Electrocardiogram for Detecting Pulmonary Hypertension
- A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or Sarcoidosis
- A Dose Escalation Study to Evaluate the Effect of RT234 in Subjects With Pulmonary Arterial Hypertension
- A Dose Response Study of UT-15C SR in Patients With Exercise-Induced Pulmonary Hypertension
- A Dose-escalation Study in Subjects With Pulmonary Arterial Hypertension (PAH)
- A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia
- A First-in-Human Study to Assess the Safety and Tolerability of PDNO
- A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234
- A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.
Approved drugs (13)
- Ambrisentan
- Bosentan
- Iloprost
- Iloprost tromethamine
- Macitentan
- Nitric oxide
- Riociguat
- Selexipag
- Sildenafil citrate
- Sitaxentan sodium
- Tadalafil
- Treprostinil
- Treprostinil sodium
Drugs in development (40)
- Albuterol Phase 3
- Anakinra Phase 1
- Bardoxolone methyl Phase 3
- BQ-123 Phase 2
- Capsaicin Phase 2
- Carvedilol Phase 2
- Dapagliflozin Phase 1
- Dapagliflozin propanediol Phase 1
- Dexmedetomidine Phase 2
- Epoprostenol Phase 3
- Escitalopram Phase 3
- Esuberaprost potassium Phase 1
- Hydroxyurea Early phase 1
- Hymecromone Phase 2
- Imatinib Phase 3
- Imatinib mesylate Phase 3
- Levosimendan Phase 2
- Losartan Phase 3
- Milrinone Phase 2
- Nifedipine Phase 3
Other linked drugs (7)
- Epoprostenol sodium
- Frespaciguat
- Regadenoson
- Sotatercept
- Telaglenastat
- Tolazoline
- Treprostinil diolamine