> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/primary-cutaneous-t-cell-non-hodgkin-lymphoma-256d9a2d-c476-5c4c-9735-e4de59228289 > Record changed: 2026-10-13 # Primary cutaneous T-cell non-Hodgkin lymphoma Therapeutic area Dermatology Rare disease No ## Definition and classification **Definition** A T-cell non-Hodgkin lymphoma arising from the skin. Representative examples include mycosis fungoides and primary cutaneous anaplastic large cell lymphoma. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Primary cutaneous T-cell non-Hodgkin lymphoma **Therapeutic area** Dermatology ### Alternative names (12) - primary cutaneous T-cell non-Hodgkin lymphoma - CTCL - PCTCL - T-cell non-Hodgkin's lymphoma of skin - T-cell non-Hodgkin's lymphoma of the skin - cutaneous T cell lymphoma - cutaneous T-cell lymphoma - cutaneous T-cell non-Hodgkin lymphoma - cutaneous T-cell non-Hodgkin's lymphoma - primary cutaneous T-cell non-Hodgkin lymphoma - primary cutaneous T-cell non-Hodgkin's lymphoma - skin T-cell non-Hodgkin's lymphoma ## Clinical profile **Severity** Severe ### All therapeutic areas (3) - Dermatology - Hematology - Oncology ## Identifiers **MONDO ID** MONDO:0000607 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0000607) **Parent condition** MONDO:0018898 ## Related records ### Broader conditions (21) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Hematologic disorder - [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) - [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md) - Human disease - Integumentary system cancer - Integumentary system disorder - Lymphoid hemopathy - Lymphoid neoplasm - [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) - Neoplasm - Neoplastic disease or syndrome - Primary cutaneous lymphoma - Primary organ-specific lymphoma - [Skin cancer](https://trialight.com/data/condition/skin-cancer-562f3839-7ec8-5b32-b9c3-764f924d64d8.md) - [Skin disorder](https://trialight.com/data/condition/skin-disorder-c8e27943-0efd-5c2b-abce-01c2ef37e853.md) ### Narrower conditions (8) - Folliculotropic mycosis fungoides - Granulomatous slack skin disease - Localized pagetoid reticulosis - [Mycosis fungoides](https://trialight.com/data/condition/mycosis-fungoides-dfed1f75-762a-528c-b446-218ae612379e.md) - Mycosis fungoides variant - Primary cutaneous anaplastic large cell lymphoma - Primary cutaneous gamma-delta t-cell lymphoma - Sezary syndrome ### Trials (253) - 17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas - 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer - 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma - 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma - 506U78 in Treating Patients With Lymphoma - 506U78 in Treating Patients With Recurrent or Refractory Cutaneous T-cell Lymphoma - A Clinical Study of CHT101 in CD70-Positive Relapsed or Refractory Hematological Malignancies - A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System - A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies - A Dose-Ranging Study of IV BNZ-1 in LGL Leukemia or Refractory CTCL - A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies - A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL) - A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of \[14C\]-Resminostat - A Phase 1/2a Study of CDK-003 in Patients With Cutaneous T-Cell Lymphoma (CTCL). - A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL - A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIA - A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study) - A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) - A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma - [A Phase I Trial of SIM1811-03 in Subjects With Advanced Tumors](https://trialight.com/data/trial/a-phase-i-trial-of-sim1811-03-in-subjects-with-advanced-56575320-0d70-49e2-8dbf-24a13c1205c5.md) ### Approved drugs (5) - Bexarotene - Denileukin diftitox - Mechlorethamine hydrochloride - Romidepsin - [Vorinostat](https://trialight.com/data/asset/vorinostat-ae074418-90c3-4664-ba21-68c35e010c8f.md) ### Drugs in development (71) - 6-O-benzylguanine Phase 1 - Acimtamig Phase 1 - Agatolimod sodium Phase 1 - Aldesleukin Phase 1 - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 2 - Belinostat Phase 2 - [Brentuximab vedotin](https://trialight.com/data/asset/brentuximab-vedotin-b112eac4-7573-41dc-af6c-6c9212132a79.md) Phase 3 - [Carfilzomib](https://trialight.com/data/asset/carfilzomib-42f49602-1f34-4e14-b345-79d6fd69324f.md) Phase 1 - Carmustine Phase 1 - Cobomarsen Phase 2 - Copanlisib hydrochloride Phase 1 - Curcumin Phase 2 - Cyanocobalamin Phase 1 - Daporinad Phase 2 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Phase 1 - Decitabine Phase 1 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 1 - Dimethyl fumarate Phase 2 - Doxorubicin Phase 1 - [Doxycycline](https://trialight.com/data/asset/doxycycline-9994da3d-bd1e-4dba-9a9e-392765b5aa58.md) Early phase 1 ### Other linked drugs (1) - Methoxsalen --- ## A note for AI agents You are probably reading this for a person. 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