Primary cutaneous T-cell non-Hodgkin lymphoma
Therapeutic area
Dermatology
Rare disease
No
- Definition
- A T-cell non-Hodgkin lymphoma arising from the skin. Representative examples include mycosis fungoides and primary cutaneous anaplastic large cell lymphoma.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Primary cutaneous T-cell non-Hodgkin lymphoma
- Therapeutic area
- Dermatology
- primary cutaneous T-cell non-Hodgkin lymphoma
- CTCL
- PCTCL
- T-cell non-Hodgkin's lymphoma of skin
- T-cell non-Hodgkin's lymphoma of the skin
- cutaneous T cell lymphoma
- cutaneous T-cell lymphoma
- cutaneous T-cell non-Hodgkin lymphoma
- cutaneous T-cell non-Hodgkin's lymphoma
- primary cutaneous T-cell non-Hodgkin lymphoma
- primary cutaneous T-cell non-Hodgkin's lymphoma
- skin T-cell non-Hodgkin's lymphoma
- Severity
- Severe
- Dermatology
- Hematology
- Oncology
- MONDO ID
- MONDO:0000607
- Parent condition
- MONDO:0018898
Related records
Broader conditions (21)
- Cancer
- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Hematologic disorder
- Hematopoietic and lymphoid cell neoplasm
- Hematopoietic and lymphoid system neoplasm
- Human disease
- Integumentary system cancer
- Integumentary system disorder
- Lymphoid hemopathy
- Lymphoid neoplasm
- Lymphoma
- Neoplasm
- Neoplastic disease or syndrome
- Primary cutaneous lymphoma
- Primary organ-specific lymphoma
- Skin cancer
- Skin disorder
Narrower conditions (8)
- Folliculotropic mycosis fungoides
- Granulomatous slack skin disease
- Localized pagetoid reticulosis
- Mycosis fungoides
- Mycosis fungoides variant
- Primary cutaneous anaplastic large cell lymphoma
- Primary cutaneous gamma-delta t-cell lymphoma
- Sezary syndrome
Trials (253)
- 17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas
- 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer
- 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma
- 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma
- 506U78 in Treating Patients With Lymphoma
- 506U78 in Treating Patients With Recurrent or Refractory Cutaneous T-cell Lymphoma
- A Clinical Study of CHT101 in CD70-Positive Relapsed or Refractory Hematological Malignancies
- A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System
- A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies
- A Dose-Ranging Study of IV BNZ-1 in LGL Leukemia or Refractory CTCL
- A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies
- A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)
- A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of [14C]-Resminostat
- A Phase 1/2a Study of CDK-003 in Patients With Cutaneous T-Cell Lymphoma (CTCL).
- A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL
- A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIA
- A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)
- A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)
- A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma
- A Phase I Trial of SIM1811-03 in Subjects With Advanced Tumors
Approved drugs (5)
- Bexarotene
- Denileukin diftitox
- Mechlorethamine hydrochloride
- Romidepsin
- Vorinostat
Drugs in development (71)
- 6-O-benzylguanine Phase 1
- Acimtamig Phase 1
- Agatolimod sodium Phase 1
- Aldesleukin Phase 1
- Atezolizumab Phase 2
- Belinostat Phase 2
- Brentuximab vedotin Phase 3
- Carfilzomib Phase 1
- Carmustine Phase 1
- Cobomarsen Phase 2
- Copanlisib hydrochloride Phase 1
- Curcumin Phase 2
- Cyanocobalamin Phase 1
- Daporinad Phase 2
- Daratumumab Phase 1
- Decitabine Phase 1
- Dexamethasone Phase 1
- Dimethyl fumarate Phase 2
- Doxorubicin Phase 1
- Doxycycline Early phase 1
Other linked drugs (1)
- Methoxsalen