> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/polycystic-ovary-syndrome-441e4a14-977c-536f-a5ad-0c5be955054b
> Record changed: 2026-11-04

# Polycystic ovary syndrome

Therapeutic area

Endocrinology

Rare disease

No

## Definition and classification

**Definition**

A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity.

**Genetic basis**

Yes

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Polycystic ovary syndrome

**Therapeutic area**

Endocrinology

### Alternative names (23)

- polycystic ovary syndrome
- Obese Subjects With Polycystic Ovary Syndrome (PCOS)
- PCOS
- PCOS (Polycystic Ovary Syndrome)
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
- PCOS (Polycystic Ovary Syndrome) of Left Ovary
- PCOS (Polycystic Ovary Syndrome) of Right Ovary
- PCOS, Insulin Resistance
- PCOS(Insulin Resistant)
- polycystic ovarian disease
- Polycystic Ovarian Syndrome (PCOS)
- polycystic ovaries
- Polycystic Ovaries Syndrome
- Polycystic Ovary Syndrome (PCOS)
- Polycystic Ovary Syndrome (PCOS) With Concurrent Nonalcoholic Fatty Liver Disease (NAFLD)
- Polycystic Ovary Syndrome (PCOS) Women
- Polycystic Ovary Syndrome (PCOS), Anovulatory Infertility
- Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder
- Polycystic Ovary Syndrome,
- Polycystic Ovary Syndrome, PCOS
- Stein-Leventhal syndrome
- PCOS1
- polycystic ovary syndrome 1

## Clinical profile

**All therapeutic areas**

- Endocrinology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0008487)

**Severity**

Mild

### Disease mechanisms (3)

- Genetic
- Hereditary
- Syndromic

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0008487)

## Identifiers

**MONDO ID**

MONDO:0008487

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0008487)

**Parent condition**

MONDO:0002254

## Related records

### Broader conditions (8)

- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of genetic or genomic mechanism
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- [Hereditary disease](https://trialight.com/data/condition/hereditary-disease-df2f8f05-e0c9-5777-8e51-c3b6639743d3.md)
- Human disease
- Syndromic disease

### Trials (962)

- "KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
- 14 Weeks Exercise Training on Lean Women With and Without PCOS
- 30000 IU Per Week Vitamin D Treatment in PCOS Patients
- 71A/G HSD17B5 SNP and Effects of Oral Contraceptive Pill in PCOS Women
- A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese
- A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS)
- A Comparison of a PULSE Diet and the TLC Diet on Reproductive, Metabolic Parameters in Women with PCOS
- A Comparison of Letrozole and Clomifene Citrate
- A Cooking and Eating Study
- A Metabolomic Study of Polycystic Ovary Syndrome With Insulin Resistance and Its Relationship With TCM Syndrome Types
- A Multi-omic Approach to Evaluate and Characterize the Polycystic Ovary Syndrome (PCOS) Phenotype
- A New Algorithm to Predict Ovarian Age
- A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS
- A Randomized Controlled Trial of Acupuncture for Insulin Resistance in Patients With Polycystic Ovary Syndrome
- A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)
- A Single Group Study to Evaluate the Effects of a Myo-Inositol and D-Chiro Inositol Supplement on Symptoms Associated With Polycystic Ovary Syndrome and Hormone Imbalance
- A Study of AZD4901 in Females With Polycystic Ovary Syndrome
- A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens
- A Study to Evaluate the Effect of Elix Cycle Balance and Daily Harmony on Polycystic Ovary Syndrome
- A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation

### Approved drugs (2)

- Clomiphene citrate
- Histrelin

### Drugs in development (100)

- Acetylcarnitine Phase 2
- Acetylcysteine Phase 2
- Anakinra Phase 2
- Arginine Phase 3
- Artenimol Phase 2
- Astaxanthin Phase 1
- Atorvastatin Phase 2
- Atorvastatin calcium Phase 2
- Bicalutamide Phase 1
- Bromocriptine Phase 3
- Cabergoline Phase 2
- [Calcium](https://trialight.com/data/asset/calcium-05275e83-0f4f-4303-8107-21a57d8d7fb9.md) Phase 3
- Canagliflozin Phase 1
- Carnitine Phase 2
- Cetrorelix Phase 3
- Cetrorelix acetate Phase 3
- Chiglitazar Phase 2
- Cholecalciferol Phase 3
- [Choriogonadotropin alfa](https://trialight.com/data/asset/choriogonadotropin-alfa-363525eb-927a-43ad-bd66-8aa43bafffa9.md) Phase 2
- Chromium Phase 3

### Other linked drugs (31)

- Acarbose
- Aklomide
- Albumin human
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md)
- Amlodipine maleate
- Berberine
- Berberine sulfate
- Bifidobacterium SPP.
- Chlormadinone acetate
- Clomiphene
- Degarelix
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md)
- Diazoxide
- Estrogen
- Fenofibrate
- Follitropin alfa
- [Hydrocortisone](https://trialight.com/data/asset/hydrocortisone-2a0db2d4-4a67-4db0-851f-091bd6b99fdb.md)
- [Leuprolide](https://trialight.com/data/asset/leuprolide-dea24d3f-b6af-4051-826c-cf4e35258f7f.md)
- [Levothyroxine](https://trialight.com/data/asset/levothyroxine-ca6d0d6d-70df-4340-bb6f-6328ecdeaf6b.md)
- Magnesium

---

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