> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/pneumonia-d2f12d4d-57c5-5c54-881e-1efe392849eb
> Record changed: 2026-10-13

# Pneumonia

Therapeutic area

Infectious Disease

Rare disease

No

## Definition and classification

**Definition**

An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Pneumonia

**Therapeutic area**

Infectious Disease

### Alternative names (2)

- pneumonia
- acute pneumonia

## Clinical profile

**Severity**

Severe

### Disease mechanisms (2)

- Acquired
- Inflammatory

### All therapeutic areas (2)

- Infectious Disease
- Pulmonology

## Identifiers

**MONDO ID**

MONDO:0005249

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005249)

**Parent condition**

MONDO:0024355

## Related records

### Broader conditions (13)

- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- Inflammatory disease
- [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md)
- [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md)
- Pneumonitis
- Respiratory system disorder
- [Respiratory tract infectious disorder](https://trialight.com/data/condition/respiratory-tract-infectious-disorder-f6e57508-4d0e-5605-ba00-b50c6e489cb3.md)

### Narrower conditions (38)

- Acute fibrinous and organizing pneumonia
- Acute interstitial pneumonia
- Anaerobic pneumonia
- [Bacterial pneumonia](https://trialight.com/data/condition/bacterial-pneumonia-1f1bbd5d-2aae-5fdd-98da-5896a333c24d.md)
- Bronchiolocentric pattern of interstitial pneumonia
- Bronchopneumonia
- Chronic eosinophilic pneumonia
- Combined pulmonary fibrosis-emphysema syndrome
- Contagious pleuropneumonia
- Cryptogenic organizing pneumonia
- Cytomegalovirus pneumonia
- Cytomegalovirus pneumonia due to NOS2 deficiency
- Desquamative interstitial pneumonia
- Eosinophilic pneumonia
- Follicular bronchiolits
- Idiopathic acute eosinophilic pneumonia
- Idiopathic chronic eosinophilic pneumonia
- Idiopathic eosinophilic pneumonia
- Idiopathic interstitial pneumonia
- Idiopathic pleuroparenchymal fibroelastosis

### Trials (1,757)

- "Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"
- 3 Days Amoxicillin Versus Placebo for Fast Breathing Childhood Pneumonia in Malawi
- 3 Days Versus 5 Days Amoxicillin for Chest-indrawing Childhood Pneumonia in Malawi
- 5 Years Mortality-rate in Patients Treated for Severe Pneumonia in an ICU - a Retrospective Study
- 64N Nutraceutical for the Prevention of Childhood Diarrhea and Pneumonia in Low Resource Settings
- 7-days Versus 14 Days of Antibiotics Therapy for Ventilator Associated Pneumonia
- A Clinical Cohort Study of Pneumonia in Respiratory Intensive Care Unit
- A Clinical Pathway for Nursing Home Acquired Pneumonia
- [A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 in Healthy Infants](https://trialight.com/data/trial/a-clinical-study-to-evaluate-the-safety-tolerability-and-3324a600-f94e-4f71-8899-6ebaa53a720b.md)
- [A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age](https://trialight.com/data/trial/a-clinical-study-to-evaluate-the-safety-tolerability-and-c4c514e9-5549-40ca-9418-bbc018269450.md)
- A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure
- A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated Pneumonia
- A Comparison of Diagnostic Approaches for Malaria and Pneumonia
- A De-Escalating Strategy for Antibiotic Treatment of Pneumonia in The Medical Intensive Care Unit (0787B-092)
- A Efficacy and Safety Study of Nasal Prongs With Proprietary Surface Coating Aiming to Reduce Bacterial Colonization
- A Feasibility Study Evaluating a Novel Mask (Nasal Reservoir Cannula)
- A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women
- A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2
- A Molecular Toolkit for the Microbial Investigation of Severe Community Acquired Pneumonia
- A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

### Approved drugs (37)

- [Amoxicillin](https://trialight.com/data/asset/amoxicillin-09050e6a-69b4-42d1-b3eb-79212edcf388.md)
- Ascorbic acid
- Azithromycin
- Aztreonam
- Bacitracin
- Cefaclor
- Cefdinir
- Cefepime hydrochloride
- Cefotaxime sodium
- Cefoxitin sodium
- Ceftaroline fosamil acetate
- Ceftazidime
- Cefuroxime sodium
- Cilastatin sodium
- Clarithromycin
- [Clavulanate potassium](https://trialight.com/data/asset/clavulanate-potassium-0c9118d2-680f-40ea-ac27-ff8ae2e79980.md)
- [Clindamycin hydrochloride](https://trialight.com/data/asset/clindamycin-hydrochloride-19a26a38-5f09-4e8b-b87a-f9ef76ca92a1.md)
- [Clindamycin phosphate](https://trialight.com/data/asset/clindamycin-phosphate-419e01e3-b65c-4586-a4bd-e2ef6ecfc03b.md)
- Cortisone acetate
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md)

### Drugs in development (108)

- [Albumin human](https://trialight.com/data/asset/albumin-human-95414b67-0d38-49d4-91b2-27b1c6c17389.md) Phase 2
- Amikacin Phase 2
- [Anakinra](https://trialight.com/data/asset/anakinra-2c0352ee-cb20-46c5-bd87-6350d9024e75.md) Phase 3
- [Apremilast](https://trialight.com/data/asset/apremilast-41723353-24b2-46d5-82cf-9e6280b6f765.md) Phase 3
- AR-105 Phase 2
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3
- Avibactam Phase 3
- [Baloxavir marboxil](https://trialight.com/data/asset/baloxavir-marboxil-95bb0047-8ebb-4242-af68-67848f77b384.md) Phase 3
- [Baricitinib](https://trialight.com/data/asset/baricitinib-dde0cdc5-8f75-41b1-bc92-b187471c63df.md) Phase 3
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2
- [Canakinumab](https://trialight.com/data/asset/canakinumab-7cd74b21-082d-4a09-8847-aa6d401bc853.md) Phase 3
- Captopril Phase 2
- Cefiderocol Phase 3
- Ceftaroline Phase 3
- Ceftobiprole Phase 1
- Ceftobiprole medocaril sodium Phase 3
- Ceftolozane Phase 3
- Ceftriaxone Phase 3
- Cefuroxime Phase 3
- Cephalosporin Phase 3

### Other linked drugs (12)

- Arbekacin
- Avibactam sodium
- Clinafloxacin
- Garenoxacin mesylate
- Lascufloxacin
- Penicillin G
- Sitafloxacin
- Tebipenem pivoxil
- Tosatoxumab
- Tosufloxacin
- Vaborbactam
- Vancomycin hydrochloride

---

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