> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/pneumococcal-infection-b3a7fc66-25ac-57f8-8fb4-073403fe8b1b
> Record changed: 2026-10-13

# Pneumococcal infection

Therapeutic area

Infectious Disease

Rare disease

No

## Definition and classification

**Definition**

Infections with bacteria of the species streptococcus pneumoniae.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Pneumococcal infection

**Therapeutic area**

Infectious Disease

### Alternative names (13)

- pneumococcal infection
- Streptococcus pneumoniae caused disease or disorder
- Streptococcus pneumoniae disease or disorder
- Streptococcus pneumoniae infectious disease
- pneumococcal infection
- Streptococcus pneumoniae infection
- Streptococcus pneumoniae infections
- infection, Streptococcus pneumoniae
- infection, pneumococcal
- infections, Streptococcus pneumoniae
- infections, pneumococcal
- pneumoniae infection, Streptococcus
- pneumoniae infections, Streptococcus

## Clinical profile

**Disease mechanisms**

- Acquired

**All therapeutic areas**

- Infectious Disease

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0005114

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005114)

**Parent condition**

MONDO:0021680

## Related records

### Broader conditions (8)

- [Bacterial infectious disease](https://trialight.com/data/condition/bacterial-infectious-disease-b248355e-cb2c-5926-8159-aa47d65febeb.md)
- Disease
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Gram-positive bacterial infections
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- [Streptococcal infection](https://trialight.com/data/condition/streptococcal-infection-a0e9c8b4-cd46-573c-81e7-605778524e6c.md)

### Narrower conditions (3)

- Pneumococcal meningitis
- [Streptococcal pneumonia](https://trialight.com/data/condition/streptococcal-pneumonia-d1520281-b2a3-5e88-8d11-bd868638431a.md)
- Streptococcus pneumoniae discitis

### Trials (299)

- 13 Valent Pneumococcal Conjugate Vaccine - Follow-on Study
- 13-valent Pneumococcal Conjugate Vaccine Study in Adults => 50 Years of Age in Mexico
- 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Healthy Japanese Infants
- 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Pneumococcal Vaccine-Naïve Adults 60 Years of Age and Older in Japan, Korea, and Taiwan
- 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 3-Dose Series in Healthy Infants
- 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 4-Dose Series in Healthy Infants
- 20-valent Pneumococcal Conjugate Vaccine Safety Study in Healthy Infants
- 9-valent CRM 197 Pneumococcal
- [A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)](https://trialight.com/data/trial/a-clinical-study-of-novel-pneumococcal-vaccine-v118c-in-d6487b9b-a525-4860-bc13-9338ed58336d.md)
- A Clinical Study of the V116 Vaccine for Children and Teenagers (V116-013)
- [A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 in Healthy Infants](https://trialight.com/data/trial/a-clinical-study-to-evaluate-the-safety-tolerability-and-3324a600-f94e-4f71-8899-6ebaa53a720b.md)
- [A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age](https://trialight.com/data/trial/a-clinical-study-to-evaluate-the-safety-tolerability-and-c4c514e9-5549-40ca-9418-bbc018269450.md)
- A Clinical Trial of 23-valent Pneumococcal Polysaccharide Vaccine
- A Clinical Trial of the 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/Tetanus Toxoid)
- A Clinical Trial to Evaluate the Immunogenicity and Safety of the 23-valent Pneumococcal Polysaccharide Vaccine in Healthy People
- A Clinical Trial to Observe the Safety of 23-Valent Pneumococcal Polysaccharide Vaccine in Target Population
- A Controlled Human Pneumococcal Infection Model (PIM) Study
- A Double-Blind Placebo-Controlled Trial of the Safety and Immunogenicity of a Seven Valent Pneumococcal Conjugate Vaccine in Presumed HIV-Infected Infants
- A Phase 1, Randomized, Controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Healthy Adults Aged 18 to 49 Years
- A Phase 1b Clinical Trial of 13-valent Pneumococcal Polysaccharide Conjugate Vaccine

### Approved drugs (4)

- [Streptococcus pneumoniae polysaccharide conjugated to corynebacterium diphtheriae CRM197](https://trialight.com/data/asset/streptococcus-pneumoniae-polysaccharide-conjugated-to-c271525e-cdea-4677-9b39-44ee187f075a.md)
- Streptococcus pneumoniae polysaccharide conjugated to corynebacterium diphtheriae toxoid
- Streptococcus pneumoniae polysaccharide conjugated to haemophilus influenzae protein D
- Streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid

### Drugs in development (7)

- [Elasomeran](https://trialight.com/data/asset/elasomeran-7d917cbd-1f45-43e8-a188-fd6dec78e983.md) Phase 3
- [Influenza virus vaccine](https://trialight.com/data/asset/influenza-virus-vaccine-99390506-afe0-4b83-a4c7-b7a43c41cb19.md) Phase 3
- KP-1461 Phase 2
- Penicillin G Phase 3
- [Pertussis vaccine](https://trialight.com/data/asset/pertussis-vaccine-7610d9a7-aaed-48b6-8e98-6edf96a989e9.md) Phase 1
- [Rituximab](https://trialight.com/data/asset/rituximab-3fb73477-f618-414e-aa0a-9ccba4d6da3f.md) Phase 2
- [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 3

---

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