> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/plasmodium-falciparum-malaria-5e0103dd-4e60-581d-924b-3435883b51f8 > Record changed: 2026-10-13 # Plasmodium falciparum malaria Therapeutic area Hematology Rare disease No ## Definition and classification **Definition** Malaria resulting from infection by Plasmodium falciparum. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Plasmodium falciparum malaria **Therapeutic area** Hematology ### Alternative names (5) - Plasmodium falciparum malaria - Plasmodium falciparum malaria, unspecified - falciparum malaria - falciparum malaria \[malignant tertian\] - malignant tertian fever (finding) ## Clinical profile **Disease mechanisms** - Acquired **Severity** Severe ### All therapeutic areas (2) - Hematology - Infectious Disease ## Identifiers **MONDO ID** MONDO:0005920 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005920) **Parent condition** MONDO:0005136 ## Related records ### Broader conditions (12) - Disease - Disease by body system or component - Disease by etiologic mechanism - Disease of primarily extrinsic mechanism - Erythrocyte disorder - Hematologic disorder - Human disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) - [Malaria](https://trialight.com/data/condition/malaria-54828cac-9b96-5833-93e2-e012d4505853.md) - Parasitic infectious disease - Protozoa infectious disease - [Vector-borne disease](https://trialight.com/data/condition/vector-borne-disease-3bb0ac2f-6d8c-5d5c-9027-84b59b878a24.md) ### Trials (443) - "Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania" - A Bioequivalence Study Comparing Amodiaquine Tablet (Pfizer) To Amodiaquine Tablets (Arsuamoon-Guilin China) In Healthy Subjects - A Bioequivalence Study Comparing Camoquin® Suspension (Pfizer) To Flavoquine® Tablets (Sanofi Aventis) In Healthy Subjects - A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine Candidates - A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses - A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) - A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria - A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan - A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607 - A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™ - A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria - A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™ - A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI - A Phase 2A Study of a Novel Antimalarial Pyrrolidinamide in Adult Patients With Uncomplicated P. Falciparum Malaria - A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1 - A Phase I/IIa Study of the Safety, Immunogenicity and Efficacy of FMP2.1/AS01B, an Asexual Blood-Stage Vaccine for Plasmodium Falciparum Malaria - A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5 - A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of the Blood-stage Malaria Candidate Vaccines RH5.1 in Matrix-M and R78C in Matrix-M in Healthy UK Adults - A Randomised Trial of Artekin and Artesunate & Amodiaquine for Uncomplicated Malaria in Timika, Papua, Indonesia. - A Randomized Trial of Coartemether and Artekin for the Treatment of Uncomplicated Malaria in Papua, Indonesia. ### Approved drugs (2) - Mefloquine hydrochloride - Quinine sulfate ### Drugs in development (48) - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 3 - [Aluminum hydroxide](https://trialight.com/data/asset/aluminum-hydroxide-a0230a1f-a5e2-439f-baa2-2b988b59e46d.md) Phase 1 - Aluminum phosphate Phase 1 - Amodiaquine Phase 3 - [Amoxicillin](https://trialight.com/data/asset/amoxicillin-09050e6a-69b4-42d1-b3eb-79212edcf388.md) Phase 3 - Arginine Phase 1 - Arginine hydrochloride Phase 2 - Artefenomel Phase 2 - Artemether Phase 3 - Artenimol Phase 3 - Arterolane Phase 2 - [Artesunate](https://trialight.com/data/asset/artesunate-586f50f5-bb73-43da-8a18-5a2743da577b.md) Phase 3 - Atovaquone Phase 3 - Azithromycin Phase 3 - Chloroquine Phase 3 - Chlorproguanil Phase 3 - [Cipargamin](https://trialight.com/data/asset/cipargamin-a39a1487-b981-492f-a4bd-eef13926cc13.md) Phase 2 - Dapsone Phase 3 - DSM-265 Phase 2 - Fosmidomycin Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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