Pertussis
Therapeutic area
Pulmonology
Rare disease
Yes
- Definition
- A contagious bacterial respiratory infection caused by Bordetella pertussis. It is characterized by severe and uncontrollable cough, resulting in a whooping sound during breathing following the cough.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Pertussis
- Therapeutic area
- Pulmonology
- pertussis
- Bordetella infection
- Bordetella pertussis caused disease or disorder
- Bordetella pertussis disease or disorder
- Bordetella pertussis infection
- Bordetella pertussis infectious disease
- pertussis
- whooping cough
- Disease mechanisms
- Acquired
- Severity
- Severe
- Infectious Disease
- Pulmonology
- MONDO ID
- MONDO:0005077
- Parent condition
- MONDO:0005087
Related records
Broader conditions (10)
- Bacterial infectious disease
- Bordetellosis
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Gram-negative bacterial infections
- Human disease
- Infectious disease
- Respiratory system disorder
Trials (268)
- 10-year Follow-up After a Single Dose Acellular Pertussis Vaccination
- 2-year Follow-up After a Single Dose Acellular Pertussis Vaccination
- 3-year Follow-up After a Single Dose Acellular Pertussis Vaccination
- 5-year Follow-up After a Single Dose Acellular Pertussis Vaccination
- A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine
- A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above)
- A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component)
- A Combined Tdap Vaccine Used As A Booster Compared To Licensed Td Vaccine
- A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject
- A Multi-center Study to Determine the Prevalence and Influence of Pertussis on COPD Exacerbation in Shenzhen
- A Multi-center Study to Determine the Prevalence and Influence of Pertussis on Subacute Cough in Shenzhen
- A Multi-Site Clinical Evaluation of the ARIES Bordetella Assay in Symptomatic Patients
- A Phase 1/2 Clinical Trial of a GamLPV, a Live Intranasal Bordetella Pertussis Vaccine
- A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed
- A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents
- A Phase 4, Randomised Vaccination Study in Healthy Adults to Investigate the Effects of Acellular Pertussis Vaccine on Colonisation With Bordetella Pertussis Using Controlled Human Infection
- A Phase I Clinical Study of a GamLPV, a Live Intranasal Bordetella Pertussis Vaccine
- A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents)
- A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series
- A Phase IV Study to Assess the Safety of EupentaTM Inj
Approved drugs (6)
- Bordetella pertussis filamentous hemagglutinin
- Bordetella pertussis pertactin autotransporter
- Bordetella pertussis toxin
- Erythromycin
- Erythromycin ethylsuccinate
- Hepatitis B virus hbsag surface protein antigen
Drugs in development (3)
- Azithromycin Phase 2
- Human immunoglobulin G Phase 3
- Pertussis vaccine Phase 3