> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/peripheral-arterial-disease-660376f2-3d22-5c83-86ea-1d146307e09b > Record changed: 2026-10-13 # Peripheral arterial disease Therapeutic area Vascular Medicine Rare disease No ## Definition and classification **Definition** A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Peripheral arterial disease **Therapeutic area** Vascular Medicine ### Alternative names (4) - peripheral arterial disease - PAD - pad - peripheral arterial disorder ## Clinical profile **Severity** Moderate ### All therapeutic areas (2) - Cardiology - Vascular Medicine ## Identifiers **MONDO ID** MONDO:0005386 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005386) **Parent condition** MONDO:0000473 ## Related records ### Broader conditions (7) - Arterial disorder - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Human disease - Peripheral vascular disease - Vascular disorder ### Narrower conditions (1) - Peripheral ischemia ### Trials (1,345) - "Unifuzol®" in Patients With Peripheral Arterial Disease - 3-year Follow-up of Patients Treated With Jetstream Combined With Ranger for Calcified Femoropopliteal Lesions - 480 Biomedical Bioresorbable Scaffold System in the Treatment of de Novo Superficial Femoral Artery (SFA) Lesions - A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation - A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND) - A Clinical Study on Efficacy & Safety Profile of Propionyl-L-carnitine Tablets for Peripheral Arterial Diseases - A Clinical Trial to Evaluate the Efficacy and Safety of a Spot Stent System Used in Femoropopliteal Arteries. - A Cross-Sectional Study to Assess Walking Performance in Subjects With Peripheral Artery and End Stage Kidney Disease - A Genomic Approach for Clopidogrel in Caribbean Hispanics - A Multicenter Study of Iomeron®-400 Used With Multi-detector Computed Tomography Angiography (MDCTA) - A Multiple Ascending Dose Study of RO4905417 in Healthy Volunteers and Patients With Peripheral Arterial Disease (PAD). - A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease - A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers. - A Non-significant Risk Clinical Study to Assess Perfusion Changes With Application of a TUS for Patients With PAD - A Non-significant Risk Clinical Study: Changes in Perfusion After Therapeutic Ultrasound in Patients With PAD - A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease - A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia - a Physician-inititated Trial Investigating the iVolution Nitinol Stent - A Post-market Registry of the MARIS-stent (Invatec) Implanted in the Superficial Femoral Artery - A ProspeCtive mUlticenteR Investigation on RENzar Stent Safety and Efficacy in the Treatment of Patients With Femoro-popliteal Disease in Tuscany (CURRENT Registry) ### Approved drugs (3) - Clopidogrel bisulfate - [Rivaroxaban](https://trialight.com/data/asset/rivaroxaban-3f354e10-6d35-4989-9e00-318be65808fb.md) - Vorapaxar sulfate ### Drugs in development (54) - Actovegin Phase 3 - Alprostadil Phase 2 - Arginine Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3 - [Canakinumab](https://trialight.com/data/asset/canakinumab-7cd74b21-082d-4a09-8847-aa6d401bc853.md) Phase 2 - Carnosine Phase 3 - Cilostazol Phase 3 - Clopidogrel Phase 3 - Cocoa Phase 3 - [Colchicine](https://trialight.com/data/asset/colchicine-ae804b3e-3263-453f-abb3-ae1e813f2ccf.md) Early phase 1 - Creatine Phase 2 - [Dalcetrapib](https://trialight.com/data/asset/dalcetrapib-cc01e1b4-85ba-45ed-8edb-c960ab8aa4fb.md) Phase 3 - Dexamethasone sodium phosphate Phase 2 - Diroximel fumarate Early phase 1 - Donaperminogene seltoplasmid Phase 2 - Edetate disodium Early phase 1 - Edoxaban Phase 2 - Emiplacel Phase 2 - Fibrinolysin, human Phase 2 - [Filgrastim](https://trialight.com/data/asset/filgrastim-942bf0d3-0bf1-4bf8-9e38-81a6c277d728.md) Phase 1 ### Other linked drugs (8) - Bupivacaine - [Evolocumab](https://trialight.com/data/asset/evolocumab-ece543fe-0502-44c3-bef4-ec566503cced.md) - Iloprost - Ranolazine - [Sirolimus](https://trialight.com/data/asset/sirolimus-08da04e4-ea95-4587-95c4-83d583e56570.md) - Sitagliptin - Telmisartan - Tilarginine --- ## A note for AI agents You are probably reading this for a person. 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