> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/peptic-esophagitis-641e2fd4-029a-5edc-9799-717abc777592
> Record changed: 2026-11-04

# Peptic esophagitis

Therapeutic area

Gastroenterology

Rare disease

No

## Definition and classification

**Definition**

Inflammation of the esophagus that is caused by the reflux of gastric juice with contents of the stomach and duodenum.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Peptic esophagitis

**Alternative names**

- peptic esophagitis

**Therapeutic area**

Gastroenterology

## Clinical profile

**Disease mechanisms**

- Inflammatory

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006896)

**All therapeutic areas**

- Gastroenterology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006896)

**Severity**

Mild

## Identifiers

**MONDO ID**

MONDO:0006896

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006896)

**Parent condition**

MONDO:0001409

## Related records

### Broader conditions (12)

- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Esophageal disorder
- Esophageal ulcer
- Esophagitis
- Human disease
- Inflammatory disease
- Peptic ulcer disease
- Ulcer disease
- Upper digestive tract disorder

### Trials (121)

- 24 Hour Esophageal and Electrogastrography to Investigate the Mechanism of Reflux Esophagitis
- A Clinical Trial of Anaprazole for Treating Reflux Esophagitis.
- A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients
- A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis
- A Novel Endoloop Pre-test to Treat Gastroesophageal Reflux
- A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases
- A Phase III Clinical Trial for Efficacy and Safety Evaluation of JP-1366 Tablets on Reflux Esophagitis
- A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County)
- A Randomized, Double-Blind, Multicenter Study to Evaluate the Acid-inhibitory and Dose-response Efficacy of TAK-438 (20 mg, 40 mg) in Patients With Proton Pump Inhibitor (PPI) - Resistant Erosive Esophagitis
- A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole
- A Study of Anaprazole Sodium Enteric-coated Tablets in the Treatment of Reflux Esophagitis
- A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer
- A Study of the Effects of Multiple Doses of Dexlansoprazole, Lansoprazole, Omeprazole or Esomeprazole on the Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Participants.
- A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring
- A Study on Vonoprazan in the Real-world Clinical Practice in China
- A Study to Check the Safety of Dexlansoprazole and Learn If it Can Heal Erosive Esophagitis (EE) and Keep it Healed in Children 2 to 11 Years Old
- A Study to Compare the Pharmacokinetic Characteristics of CJ-12420
- [A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis](https://trialight.com/data/trial/a-study-to-evaluate-the-efficacy-and-safety-of-bli5100-in-51a411c3-ac7d-409a-9ab7-19948da28005.md)
- A Study to Evaluate the Long-Term Safety of BLI5100 in Patients With Gastroesophageal Reflux Disease
- A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008

### Approved drugs (2)

- Esomeprazole magnesium
- Vonoprazan fumarate

### Drugs in development (20)

- Abeprazan Phase 3
- Anaprazole Phase 3
- Anaprazole sodium Phase 2
- Dexlansoprazole Phase 3
- [Esomeprazole](https://trialight.com/data/asset/esomeprazole-852b606c-0a4e-4827-8fd8-7ca4ee307b02.md) Phase 3
- Esomeprazole potassium Phase 3
- [Famotidine](https://trialight.com/data/asset/famotidine-5721dbb9-1373-4622-a660-e27ebf480acc.md) Phase 3
- Ilaprazole Phase 2
- Lafutidine Phase 3
- Lanreotide Phase 2
- Lansoprazole Phase 3
- Linaprazan Phase 2
- Netazepide Phase 1
- [Omeprazole](https://trialight.com/data/asset/omeprazole-042440e1-a0fc-438d-a87b-7f2e8fa68dad.md) Phase 3
- Omeprazole magnesium Phase 3
- Omeprazole sodium Phase 3
- [Rabeprazole](https://trialight.com/data/asset/rabeprazole-c1f8c7ed-cc36-469a-a527-ead5eea1412a.md) Phase 3
- Rabeprazole sodium Phase 2
- Ranitidine Phase 1
- Tenatoprazole Phase 2

### Other linked drugs (2)

- Chlorpromazine
- Vonoprazan

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