> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/penile-cancer-6334d2a3-450f-5db8-b8d0-5bc607b87b2e > Record changed: 2026-10-13 # Penile cancer Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A primary or metastatic malignant neoplasm that affects the penis. Representative examples include penile carcinoma and penile sarcoma. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Penile cancer **Therapeutic area** Oncology ### Alternative names (15) - penile cancer - penile neoplasm - cancer of penis - malignant neoplasm of penis - malignant neoplasm of the penis - malignant penile neoplasm - malignant penile tumor - malignant penile tumour - malignant penis neoplasm - malignant tumor of penis - malignant tumor of the penis - malignant tumour of penis - malignant tumour of the penis - penile cancer - penis cancer ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Oncology - Reproductive Health ## Identifiers **MONDO ID** MONDO:0001325 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001325) **Parent condition** MONDO:0005836 ## Related records ### Broader conditions (16) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - Male reproductive organ cancer - Male reproductive system disorder - Male reproductive system neoplasm - Neoplasm - Neoplastic disease or syndrome - Penile disorder - [Penile neoplasm](https://trialight.com/data/condition/penile-neoplasm-13ea08e2-9cce-5ce2-9cc1-bd1ffcca5c3d.md) - Reproductive system cancer - Reproductive system disorder - Reproductive system neoplasm ### Narrower conditions (16) - Basaloid carcinoma of the penis - Glans penis cancer - Human papillomavirus-related penile squamous cell carcinoma - Non-invasive verrucous carcinoma of the penis - Paget disease of the penis - Papillary carcinoma of the penis - Penile carcinoma - Penile sarcoma - Penile urethral cancer - Penis basal cell carcinoma - Penis carcinoma in situ - Penis mixed squamous cell carcinoma - Penis verrucous carcinoma - Sarcomatoid penile squamous cell carcinoma - Squamous cell carcinoma of penis - Warty carcinoma of the penis ### Trials (57) - A Chatbot Intervention for Reducing HPV Vaccine Hesitancy - A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination - A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest - A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers - A PHASE II, RANDOMIZED STUDY TO ASSESS MAINTENANCE THERAPY WITH CEMIPLIMAB VERSUS BEST SUPPORTIVE CARE AFTER 1ST LINE PLATINUM-BASED CHEMOTHERAPY IN ADVANCED/RECURRENT PENILE CANCER - [A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males](https://trialight.com/data/trial/a-phase-iii-study-to-evaluate-the-efficacy-immunogenicity-219c05bd-7219-460e-afb4-31c216079542.md) - A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy - A Study of Becotatug Vedotin Combined With Pucotenlimab in the Treatment of EGFR-Positive Advanced Penile Cancer - Assessment of Patient Experience and Needs for Patients Undergoing Invasive Inguinal Lymph Node Procedures for Penile Cancer - Cancer in Patients With Gabapentin (GPRD) - CaptHPV : Validation of the Method "CaptHPV" for the Diagnosis of Human Papillomavirus Associated Infiltrating Carcinomas - Carboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile Cancer - DEfeating PEnile CAncer-2 - Development of Diagnostics and Treatment of Urological Cancers - E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers - E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers - Education, Immigration and HPV Vaccination: an Informational Randomized Trial - Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations - Efficacy of INCMGA00012 in Penile Squamous Cell Carcinoma (ORPHEUS) - EGFR-ADC (Becotatug Vedotin) Combined With PD-1 Inhibitor (Pucotenlimab) in Neoadjuvant Treatment of Advanced Penile Cancer ### Drugs in development (12) - Bintrafusp alfa Phase 1 - [Cemiplimab](https://trialight.com/data/asset/cemiplimab-1c235a93-9b2c-4db0-9980-a78a93354b46.md) Phase 2 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2 - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 2 - Entinostat Phase 1 - Ifosfamide Phase 2 - Immunocytokine nhs-IL12 Phase 1 - [Irinotecan hydrochloride](https://trialight.com/data/asset/irinotecan-hydrochloride-c1f6b7df-7c76-40f1-92fe-12d71b1f3b25.md) Phase 2 - Nimotuzumab Phase 2 - [Paclitaxel](https://trialight.com/data/asset/paclitaxel-889db92c-df97-46a6-bf1c-74974a87fa75.md) Phase 2 - [Retifanlimab](https://trialight.com/data/asset/retifanlimab-57767872-c97a-4714-befa-fa3aa2ae5ce8.md) Phase 2 - [Toripalimab](https://trialight.com/data/asset/toripalimab-92e6b353-a6c4-4e1e-a99f-559038ba7177.md) Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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