> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/pancreatic-adenosquamous-carcinoma-3bc99d24-2067-5875-b515-fdda19e7f620 > Record changed: 2026-11-04 # Pancreatic adenosquamous carcinoma Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** A carcinoma that arises from the pancreas showing both ductal and squamous differentiation. The squamous component should represent at least 30% of the malignant cellular infiltrate. The prognosis is usually worse than that of ductal adenocarcinoma. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Pancreatic adenosquamous carcinoma **Therapeutic area** Oncology ### Alternative names (10) - pancreatic adenosquamous carcinoma - adenosquamous carcinoma of pancreas - adenosquamous carcinoma of the pancreas - adenosquamous pancreas carcinoma - pancreas adenosquamous carcinoma - pancreatic adenoacanthoma - pancreatic adenosquamous cancer - pancreatic mixed squamous and adenocarcinoma - pancreatic mucoepidermoid carcinoma - PAASC ## Clinical profile **Severity** Severe ### All therapeutic areas (3) - Endocrinology - Gastroenterology - Oncology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005614) ## Identifiers **MONDO ID** MONDO:0005614 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005614) **Parent condition** MONDO:0006074 ## Related records ### Broader conditions (25) - Adenosquamous carcinoma - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Digestive system cancer - Digestive system carcinoma - [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md) - [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md) - Epithelial neoplasm - Exocrine pancreatic carcinoma - Human disease - Malignant exocrine pancreas neoplasm - [Malignant pancreatic neoplasm](https://trialight.com/data/condition/malignant-pancreatic-neoplasm-5dd0b53e-5962-50ea-a2e5-cf2444bd0485.md) - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - Pancreas disorder ### Trials (11) - APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation - Expanded Access Program for Daraxonrasib (RMC-6236) in Previously Treated Metastatic Pancreatic Adenocarcinoma - Samuraciclib in Combination With Gemcitabine/Nab-Paclitaxel in Patients With Metastatic Basal-Like Pancreatic Cancer - [Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma](https://trialight.com/data/trial/study-of-daraxonrasib-and-daraxonrasib-gnp-as-first-line-4272d760-c06f-432f-94ac-f58a87cc77a1.md) - Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma - Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 ) - Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP) - Switch Maintenance in Pancreatic - Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer - Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma - The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer ### Drugs in development (3) - Minnelide Phase 2 - Pemigatinib Phase 2 - [Retifanlimab](https://trialight.com/data/asset/retifanlimab-57767872-c97a-4714-befa-fa3aa2ae5ce8.md) Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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