Open-angle glaucoma
Therapeutic area
Ophthalmology
Rare disease
No
- Definition
- Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Open-angle glaucoma
- Therapeutic area
- Ophthalmology
- open-angle glaucoma
- POAG
- glaucoma, primary open angle
- open angle glaucoma
- pigmentary glaucoma
- primary open angle glaucoma
- All therapeutic areas
- Ophthalmology
- Severity
- Severe
- MONDO ID
- MONDO:0005338
- Parent condition
- MONDO:0005041
Related records
Broader conditions (7)
- Disease
- Disease by body system or component
- Disorder of orbital region
- Disorder of visual system
- Eye disorder
- Glaucoma
- Human disease
Narrower conditions (13)
- Glaucoma 1, open angle, A
- Glaucoma 1, open angle, J
- Glaucoma 1, open angle, K
- Glaucoma 1, open angle, l
- Glaucoma 1, open angle, M
- Glaucoma 1, open angle, N
- Glaucoma 1, open angle, O
- Glaucoma 1, open angle, P
- Glaucoma type 1C
- Juvenile open angle glaucoma
- Low tension glaucoma
- OPTN-related open angle glaucoma
- Residual stage of open angle glaucoma
Trials (917)
- [KJ-TFC-005] Phase 3 Study, Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
- 18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)
- 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma
- 24 Hour IOP Lowering Efficacy of AL-3789
- 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
- 24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration.
- 24-hour Efficacy of AR-12286
- 24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients
- 24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed Combination
- 24-hour IOP-lowering Effect of Brimonidine 0.1%
- 24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed Combinations
- 24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
- 24-hr Intraocular Pressure Control With Dorzolamide/Timolol vs the Brimonidine/Timolol Fixed Combination
- 24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation Tonometry
- 5-Year Postoperative Outcomes of Patients Who Completed the CREST Study
- A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma
- A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension
- A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma
- A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma
- A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma
Approved drugs (17)
- Betaxolol hydrochloride
- Bimatoprost
- Brimonidine tartrate
- Brinzolamide
- Carteolol hydrochloride
- Dapiprazole hydrochloride
- Dorzolamide hydrochloride
- Latanoprost
- Latanoprostene bunod
- Methazolamide
- Netarsudil dimesylate
- Omidenepag isopropyl
- Pilocarpine
- Tafluprost
- Timolol
- Timolol maleate
- Travoprost
Drugs in development (21)
- Anecortave acetate Phase 2
- Betaxolol Phase 3
- Bimatoprost grenod Phase 2
- Brimonidine Phase 2
- Citicoline Phase 3
- DE-104 Phase 2
- Dorzolamide Phase 3
- Evodenoson Phase 1
- Fluorouracil Phase 3
- Ginkgo Phase 2
- Memantine Phase 3
- Mitomycin Phase 2
- Netarsudil Early phase 1
- Niacinamide Phase 2
- Ofloxacin Phase 3
- Prednisolone Phase 3
- Pyruvate Phase 2
- Ranibizumab Phase 1
- Sodium chloride Phase 2
- Trabodenoson Phase 3
Other linked drugs (4)
- Demecarium bromide
- Levobunolol
- Metformin
- Metipranolol