> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/ocular-hypertension-754666dc-b494-5a18-a3ee-6a2d941c65dd
> Record changed: 2026-10-13

# Ocular hypertension

Therapeutic area

Ophthalmology

Rare disease

No

## Definition and classification

**Definition**

Abnormally high intraocular pressure.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Ocular hypertension

**Alternative names**

- ocular hypertension

**Therapeutic area**

Ophthalmology

## Clinical profile

**Severity**

Mild

### All therapeutic areas (3)

- Cardiology
- Ophthalmology
- Vascular Medicine

## Identifiers

**MONDO ID**

MONDO:0006875

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006875)

**Parent condition**

MONDO:0005044

## Related records

### Broader conditions (10)

- Arterial disorder
- [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md)
- Disease
- Disease by body system or component
- Disorder of orbital region
- Disorder of visual system
- Eye disorder
- Human disease
- [Hypertensive disorder](https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5.md)
- Vascular disorder

### Trials (650)

- \[KJ-TFC-005\] Phase 3 Study, Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
- 1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT
- 18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)
- 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma
- 24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension
- 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
- 24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration.
- 24-hour Efficacy of AR-12286
- 24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients
- 24-hour IOP-lowering Effect of 0.01% Bimatoprost
- 24-hour IOP-lowering Effect of Brimonidine 0.1%
- 24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
- 6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension
- A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma
- A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension
- A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma
- A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma
- A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma
- A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)
- A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertension

### Approved drugs (14)

- Betaxolol hydrochloride
- [Bimatoprost](https://trialight.com/data/asset/bimatoprost-6eef0f4d-2227-4a51-94e0-7508a5f1c01b.md)
- Brimonidine tartrate
- Brinzolamide
- Dorzolamide hydrochloride
- [Latanoprost](https://trialight.com/data/asset/latanoprost-70b1bf55-247c-476b-a7ee-5a056ee0cddd.md)
- Latanoprostene bunod
- Netarsudil dimesylate
- Omidenepag isopropyl
- Pilocarpine
- Tafluprost
- Timolol
- [Timolol maleate](https://trialight.com/data/asset/timolol-maleate-d3b5d7ee-d8f2-4ddd-9168-1f49a7b9f34b.md)
- Travoprost

### Drugs in development (19)

- AMA0076 Phase 2
- AZD-4017 Phase 2
- Bamosiran Phase 2
- Betaxolol Phase 3
- Bimatoprost grenod Phase 1
- Brimonidine Phase 3
- DE-104 Phase 2
- Dorzolamide Phase 3
- Evodenoson Phase 1
- Levobetaxolol hydrochloride Phase 3
- Ofloxacin Phase 3
- Phenylephrine Phase 1
- Piclidenoson Phase 2
- [Prednisolone](https://trialight.com/data/asset/prednisolone-783fce19-b285-4835-90c3-3db5a6364414.md) Phase 3
- SAD448 Phase 1
- Simenepag isopropyl Phase 2
- Trabodenoson Phase 3
- Tropicamide Phase 1
- Verosudil Phase 2

### Other linked drugs (4)

- Carteolol
- Carteolol hydrochloride
- [Netarsudil](https://trialight.com/data/asset/netarsudil-cdf69483-92c3-4ac8-b941-7366b7bf529a.md)
- Ripasudil hydrochloride dihydrate

---

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