> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/obstructive-sleep-apnea-syndrome-02928491-a2d7-50f4-a4b7-30b79e6771ff > Record changed: 2026-10-13 # Obstructive sleep apnea syndrome Therapeutic area Pulmonology Rare disease No ## Definition and classification **Definition** Cessation of air flow during sleep due to upper airway obstruction. **Genetic basis** Yes **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Obstructive sleep apnea syndrome **Therapeutic area** Pulmonology ### Alternative names (14) - obstructive sleep apnea syndrome - obstructive sleep apnea - obstructive sleep apnea syndrome - Apneas, obstructive sleep - OSAHS - apnea, obstructive sleep - obstructive sleep Apneas - sleep Apneas, obstructive - sleep apnea hypopnea syndrome - sleep apnea syndrome, obstructive - syndrome, obstructive sleep apnea - syndrome, sleep apnea, obstructive - syndrome, upper airway resistance, sleep apnea - upper airway resistance sleep apnea syndrome ## Clinical profile **Disease mechanisms** - Syndromic **All therapeutic areas** - Pulmonology **Severity** Mild ## Identifiers **MONDO ID** MONDO:0007147 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0007147) **Parent condition** MONDO:0002254 ## Related records ### Broader conditions (9) - Disease - Disease by body system or component - Disease by developmental or physiological process - Human disease - Respiratory system disorder - Sleep apnea syndrome - Sleep disorder - Sleep-wake disorder - Syndromic disease ### Narrower conditions (1) - Complex sleep apnea ### Trials (2,140) - "A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA" - "Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved" - "Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" - "Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" - 12-week Tele-exercise Program in Patients With OSA - 19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome - 3D Printer Modified CPAP Mask for Obstructive Sleep Apnea - 3D Volumetric Changes in the Upper Airway After MMA in OSAS Patients and the Implication on QOL: A Prospective Registry - 3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea - A 2 Week, Crossover Trial of Dietary Nitrate in Obstructive Sleep Apnoea Syndrome (OSAS). - A Brief Lifestyle Modification Programme in Overweight Subjects With Obstructive Sleep Apnoea - Needs Assessment - A Cardiosleep Research Program on Obstructive Sleep Apnea, Blood Pressure Control and Maladaptive Myocardial Remodeling - A Cohort Study on Increasing Blood Pressure Benefits in Sleep Apnea Patients After CPAP Treatment - A Community Study of the Risk for Obstructive Sleep Apnea and Respiratory Inflammation in an Adult Chinese Population - A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in Adults - A Comparison of CPAP With and Without Humidification: A Pilot Study - A Comparison of Surgical Outcome Following Drug-induced Sleep Endoscopic Diagnosis Using Propofol or Dexmedetomidine for Sedation : A Prospective Randomized Trial - A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea - A Cross-sectional Study of the Occurrence and Effect of Obstructive Sleep Apnea in Subjects With Resistant Hypertension - A Development Study to Evaluate a Full-Face Mask for the Treatment of Obstructive Sleep Apnea ### Approved drugs (4) - Armodafinil - Modafinil - Pitolisant hydrochloride - Solriamfetol hydrochloride ### Drugs in development (52) - Acetazolamide Phase 2 - [Aroxybutynin](https://trialight.com/data/asset/aroxybutynin-777dd7fe-7007-406f-b4f5-210ed05e94c2.md) Phase 3 - Atomoxetine Phase 2 - [Atomoxetine hydrochloride](https://trialight.com/data/asset/atomoxetine-hydrochloride-ec642fa5-6de5-4361-a5d5-ba620d2a4aef.md) Phase 2 - Atorvastatin Phase 2 - [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md) Phase 3 - Calcifediol Phase 2 - Dalfampridine Phase 2 - Danavorexton Phase 1 - Daridorexant Phase 1 - Desipramine Phase 2 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3 - Dexmedetomidine Phase 3 - Dimethyl fumarate Phase 2 - [Dronabinol](https://trialight.com/data/asset/dronabinol-b3414807-1cde-4111-8024-a7a366127956.md) Phase 2 - Eszopiclone Phase 2 - Fentanyl Phase 3 - Gefapixant Phase 1 - Ibuprofen Phase 3 - Lemborexant Phase 1 ### Other linked drugs (6) - Allopurinol - Ketorolac - Lidocaine hydrochloride - Nalbuphine - Retinol - Vitamin E --- ## A note for AI agents You are probably reading this for a person. 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