> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/non-small-cell-lung-carcinoma-a86c1d60-523f-5ea7-a5e1-39ed4a2296f8 > Record changed: 2026-10-13 # Non-small cell lung carcinoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Non-small cell lung carcinoma **Therapeutic area** Oncology ### Alternative names (10) - non-small cell lung carcinoma - NSCLC - NSCLC - non-small cell lung cancer - non-small cell cancer of lung - non-small cell cancer of the lung - non-small cell carcinoma of lung - non-small cell carcinoma of the lung - non-small cell lung cancer - non-small cell lung carcinoma - non-small cell lung carcinoma (disease) ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Oncology - Pulmonology ## Identifiers **MONDO ID** MONDO:0005233 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005233) **Parent condition** MONDO:0005138 ## Related records ### Broader conditions (20) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Human disease - [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md) - [Lung cancer](https://trialight.com/data/condition/lung-cancer-c4ca1fe0-9b3d-5957-a668-2d6cf26bd16a.md) - [Lung carcinoma](https://trialight.com/data/condition/lung-carcinoma-8cf46a3c-0bd0-5247-adda-142fcb8391aa.md) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - [Lung neoplasm](https://trialight.com/data/condition/lung-neoplasm-d4ce75ac-7517-5ab7-9f47-34c0f7b81786.md) - Neoplasm - Neoplasm of thorax - Neoplastic disease or syndrome - Respiratory system cancer - Respiratory system disorder - [Respiratory tract neoplasm](https://trialight.com/data/condition/respiratory-tract-neoplasm-2d8277a2-2395-521a-b14a-4b620139fe2d.md) - [Thoracic cancer](https://trialight.com/data/condition/thoracic-cancer-bb0f3b17-0261-5157-830c-759d6c71e62b.md) ### Narrower conditions (38) - Acinar lung adenocarcinoma - Adenosquamous lung carcinoma - Basaloid large cell lung carcinoma - Bronchus mucoepidermoid carcinoma - Classic pulmonary blastoma - Epithelial predominant pulmonary blastoma - Fetal lung interstitial tumor - Large cell carcinoma with rhabdoid phenotype - Large cell lung carcinoma, clear cell variant - [Lung adenocarcinoma](https://trialight.com/data/condition/lung-adenocarcinoma-1cff3624-1dd5-5076-89a7-1f8a28c087a6.md) - Lung adenocarcinoma in situ - Lung adenoid cystic carcinoma - Lung colloid adenocarcinoma - Lung combined large cell neuroendocrine carcinoma - Lung combined type small cell adenocarcinoma - Lung giant cell carcinoma - Lung large cell carcinoma - Lung occult adenocarcinoma - Lung occult large cell carcinoma - Lung pleomorphic carcinoma ### Trials (7,651) - --SuPERIOR Trial-- - -02341066 and PF-00299804 for Advanced Non-Small Cell Lung Cancer - 'SOURCE - LUNG' Stereotactic Ablative Radiation Therapy Of UltRaCEntral LUNG Tumours (SOURCE Lung) - (Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations - (HARMONY) Study of BLU-701 in EGFR-mutant NSCLC - (SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC - \[177Lu\]Lu-AKIR001 First-in-human Study - \[18F\]-AraG for the Detection of T-Cell Activation in Advanced Non-small Cell Lung Cancer Patients Undergoing PD-1/PD-L1-Directed Therapy - \[18F\]F-AraG PET Imaging to Visualize Tumor Infiltrating T-cell Activation in Non-small Cell Lung Cancer. - \[18F\]F-AraG/Total Body PET Imaging and Healthy Subjects and Lung Cancer Patients - \[68Ga\]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR) - \[68Ga\]Ga-NOTA-RW102 PET Imaging in the Diagnosis of PD-L1-expressing Lung Cancer - 0822GCC: Phase 2 Study of Efficacy and Safety of Apricoxib/Placebo With Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer - 10-Propargyl-10-Deazaaminopterin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer - 125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer - 13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer - 131-I-TM-601 Study in Adults With Solid Tumors - 131I-L19SIP Radioimmunotherapy Combined With Radiochemotherapy in Patients With Locally-advanced Non Small Cell Lung Cancer (NSCLC) - 177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors - 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors ### Approved drugs (41) - [Adagrasib](https://trialight.com/data/asset/adagrasib-550c7524-1104-4d43-9827-298e1041dc2e.md) - Afatinib dimaleate - Alectinib hydrochloride - [Amivantamab](https://trialight.com/data/asset/amivantamab-94d99890-d90e-4d89-8a02-036a29458456.md) - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) - Brigatinib - Capmatinib hydrochloride - Ceritinib - Crizotinib - Dacomitinib - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) - Docetaxel anhydrous - [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) - Entrectinib - Erlotinib hydrochloride - Gefitinib - Gemcitabine hydrochloride - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) - [Lazertinib mesylate](https://trialight.com/data/asset/lazertinib-mesylate-6e43140e-9e73-4520-9ea0-544e8808c3bb.md) ### Drugs in development (698) - \[18F\]FLUOROMISONIDAZOLE Phase 2 - [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 3 - Abequolixron Phase 1 - [Abiraterone acetate](https://trialight.com/data/asset/abiraterone-acetate-2c6662c6-31e9-49ed-a022-f76f326fbd3e.md) Phase 1 - Abivertinib Phase 3 - Abivertinib maleate Phase 3 - ABT-510 Phase 2 - ABT-751 Phase 2 - Acalabrutinib Phase 2 - Acapatamab Phase 1 - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 2 - Acetylcarnitine Phase 3 - Acyclovir sodium Phase 2 - Adavosertib Phase 2 - [Adebrelimab](https://trialight.com/data/asset/adebrelimab-047820dd-1777-483d-90ab-dd5fc86f78f6.md) Phase 2 - Adenosine diphosphate Phase 1 - ADG-106 Phase 1 - AEG-35156 Phase 1 - Afatinib Phase 3 - [Aflibercept](https://trialight.com/data/asset/aflibercept-6bb09e87-ca99-436b-8634-71b90510b8fb.md) Phase 1 ### Other linked drugs (18) - Anamorelin hydrochloride - Bafisontamab - CEP-9722 - Cysteine - Galunisertib - Garsorasib - Iopofosine I 131 - Iruplinalkib - MP-0250 - Nimesulide - NM-404 I-124 - Radretumab - RX-518 - SNX 5422 - Surzebiclimab - [Telisotuzumab adizutecan](https://trialight.com/data/asset/telisotuzumab-adizutecan-73d60959-a437-4a12-a662-43fd6fc3da77.md) - Tulmimetostat - XMT-1592 --- ## A note for AI agents You are probably reading this for a person. 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