> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/newborn-respiratory-distress-syndrome-09475735-1d09-548f-9261-b73619bb9db3 > Record changed: 2026-10-13 # Newborn respiratory distress syndrome Therapeutic area Pulmonology Rare disease No ## Definition and classification **Definition** A condition beginning in the first day of life that results from inadequate surfactant production, causing increased work of breathing and impaired gas exchange. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Newborn respiratory distress syndrome **Therapeutic area** Pulmonology ### Alternative names (22) - newborn respiratory distress syndrome - RDS - respiratory distress syndrome - RDS Of newborns - RDS, respiratory distress syndrome Of newborns - hyaline membrane disease - infant ARDS - infant acute respiratory distress syndrome - infant respiratory distress syndrome - neonatal respiratory distress - neonatal respiratory distress syndrome - newborns (RDS), respiratory distress syndrome Of - respiratory distress syndrome Of newborns - respiratory distress syndrome Of newborns (RDS) - respiratory distress syndrome in the newborn - respiratory distress syndrome of newborn - syndrome Of newborns (RDS), respiratory distress - RDS of prematurity - respiratory distress syndrome in premature infants - NRDS - RDS - infants - respiratory distress syndrome, infant ## Clinical profile **Disease mechanisms** - Syndromic **All therapeutic areas** - Pulmonology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0700081 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0700081) **Parent condition** MONDO:0017015 ## Related records ### Broader conditions (15) - Acute disease - [Acute respiratory distress syndrome](https://trialight.com/data/condition/acute-respiratory-distress-syndrome-8dc4b74c-8356-5dfd-bfa3-258d9d1e44ab.md) - [Acute respiratory failure](https://trialight.com/data/condition/acute-respiratory-failure-a4d08df7-7f5c-558c-9da0-305072fe16fe.md) - Disease - Disease by body system or component - Human disease - [Interstitial lung disease](https://trialight.com/data/condition/interstitial-lung-disease-745f5770-ba0b-517d-b691-5b9731a03266.md) - Interstitial lung disease specific to childhood - [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - Pediatric acute respiratory distress syndrome - Primary interstitial lung disease specific to childhood - Respiratory failure - Respiratory system disorder - Syndromic disease ### Narrower conditions (1) - Respiratory distress syndrome in premature infants ### Trials (1,526) - "Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory Distress syndrOme" - "Effectiveness of Delivery Room Bubble CPAP in Preterm Infants With Respiratory Distress - (S5-SAMU) Randomized Study Comparing the ASV (Adaptative Support Ventilation) to Conventional Ventilation - 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDS - A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+) - A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS - A Clinical Study on Levosimendan Improvement of Prognosis of ARDS Patients by Optimizing Pulmonary Hemodynamics - A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome - A Clinical Trial to Evaluate the Safety of agenT-797 in COVID-19 Participants With ARDS - A Comparative Study Between Postextubation of Preterm Infants Into High-Flow Nasal Cannulae V.S Nasal Continuous Positive Airway Pressure - A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome - A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation - A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients - A Comparison of Optimal PEEP Determination Guided by EIT and G5 Device in Moderate and Severe ARDS Patients - A Dose Escalation Study of NanO2 in Patients With Mild Respiratory Distress - A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact - A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC) - A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits - A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies - A Multi-center Trial to Determine if Curosurf® Reduces the Duration of Mechanical Ventilation in Very Preterm Infants ### Approved drugs (4) - Beractant - Calfactant - Colfosceril palmitate - Poractant alfa ### Drugs in development (7) - [Beclomethasone dipropionate](https://trialight.com/data/asset/beclomethasone-dipropionate-068d01cb-b921-4eda-85ad-1921f6683476.md) Phase 3 - Betamethasone Phase 2 - [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md) Phase 3 - Lucinactant Phase 2 - [Nitric oxide](https://trialight.com/data/asset/nitric-oxide-b0556c6a-c162-4042-9833-36420fc1d67c.md) Phase 3 - [Propofol](https://trialight.com/data/asset/propofol-11b6d3dc-8bdb-4f05-a143-ae26c38c4af2.md) Phase 3 - [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 2 ### Other linked drugs (4) - Caffeine citrate - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) - Dexmedetomidine - Protirelin --- ## A note for AI agents You are probably reading this for a person. 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