> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/neutropenia-30a0ef48-7a8d-552c-a177-b3165712f377
> Record changed: 2026-11-04

# Neutropenia

Therapeutic area

Hematology

Rare disease

No

## Definition and classification

**Definition**

A decrease in the number of neutrophils found in the blood.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Neutropenia

**Therapeutic area**

Hematology

### Alternative names (8)

- neutropenia
- Fever and Neutropenia
- Neutropenia (Low White Blood Cell Count)
- Neutropenia and Fever
- Neutropenia, Chemotherapy-Induced Febrile
- Neutropenia, Febrile
- Neutropenia, Severe Congenital, Autosomal Recessive 3
- neutropenic disorder

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Hematology
- Immunology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001475)

## Identifiers

**MONDO ID**

MONDO:0001475

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001475)

**Parent condition**

MONDO:0001609

## Related records

### Broader conditions (8)

- Agranulocytosis
- Disease
- Disease by body system or component
- Hematologic disorder
- Human disease
- [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md)
- Leukocyte disorder
- Leukopenia

### Narrower conditions (39)

- Autosomal dominant severe congenital neutropenia
- Autosomal recessive severe congenital neutropenia
- Autosomal recessive severe congenital neutropenia due to CSF3R deficiency
- Autosomal recessive severe congenital neutropenia due to CXCR2 deficiency
- Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency
- Autosomal recessive severe congenital neutropenia due to JAGN1 deficiency
- Barth syndrome
- Chediak-Higashi syndrome
- Cohen syndrome
- Congenital neutropenia-myelofibrosis-nephromegaly syndrome
- Constitutional neutropenia
- Cyclic neutropenia
- ELANE-related neutropenia
- Glycogen storage disease Ib
- Griscelli syndrome type 2
- Hermansky-Pudlak syndrome 2
- Kostmann syndrome
- Lichtenstein syndrome
- Neonatal alloimmune neutropenia
- Neutropenia-monocytopenia-deafness syndrome

### Trials (444)

- A Comparative Evaluation of Pharmacokinetics and Immunogenicity.
- A comparatiVe Study on Efficacy and Safety of Lipegfilgrastim in Comparison to Pegfilgrastim in Elderly Patients With Aggressive B Cell Non-HOdgkin Lymphomas at hIgh Risk for R-CHOP-21-inDuced Neutropenia
- A Comparative Study to Evaluate the Effect of HSP-130, US-approved Neulasta and EU-approved Neulasta in Healthy Participants
- A Comparator Study of a Tasso Device Blood Sample to Traditional Venous Blood Sample for CBC
- A Comparison of Fluconazole and Amphotericin B in the Treatment of Fungal Infections
- A Multi-cohort Study of Efbemalenograstim Alfa Injection for Preventing ANC Reduction in Solid Tumor Patients Post Immune-chemotherapy.
- A Pharmacokinetic Study of JK1211(Itraconazole \[Itrizole\]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection
- A Pharmacokinetics/Dynamics Ib Study of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy
- A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility
- A Phase II Study Comparing Pegylated rhG-CSF（HHPG-19K） and rhG-CSF in Breast Cancer Patients Receiving Chemotherapy
- A Phase II, Dose-finding Study of F-627 in Patients With Breast Cancer Receiving Myelotoxic Chemotherapy.
- A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia
- A Pilot Study to Evaluate the Effects of Subcutaneously Administered Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor in Pediatric HIV-Infected Patients With Neutropenia Secondary to Azidothymidine
- A Pilot Study to Evaluate the Safety and Activities of EW02 in Reducing Neutropenia Caused by Chemotherapy
- A Post Marketing Surveillance Study of Lipo-AB® (Amphotericin B) in Neutropenic Patients With Persistent Fever
- A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer
- A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection.
- A Randomized, Open Label, Comparative, Multicenter Trial of Voriconazole Vs. AmBisome for Empirical Antifungal Therapy in Immunocompromised Patients With Persistent Fever and Neutropenia
- A Real World Study Evaluating the Clinical Application of PEG-rhG-CSF During Chemotherapy in Patients With Solid Tumors

### Approved drugs (5)

- Efbemalenograstim alfa
- [Filgrastim](https://trialight.com/data/asset/filgrastim-942bf0d3-0bf1-4bf8-9e38-81a6c277d728.md)
- Lipegfilgrastim
- [Pegfilgrastim](https://trialight.com/data/asset/pegfilgrastim-1d67f09f-a3d2-4dbc-bfb9-efed1a49c050.md)
- Posaconazole

### Drugs in development (73)

- Alcohol Phase 3
- [Amoxicillin](https://trialight.com/data/asset/amoxicillin-09050e6a-69b4-42d1-b3eb-79212edcf388.md) Phase 3
- Amphotericin B Phase 3
- Anakinra Phase 2
- Anidulafungin Phase 1
- [Avibactam](https://trialight.com/data/asset/avibactam-6cfff504-ee0a-4c2e-be81-39d4e7db1239.md) Phase 2
- Balugrastim Phase 2
- [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 2
- Caspofungin Phase 2
- Caspofungin acetate Phase 3
- Cefepime Phase 3
- Cefepime hydrochloride Phase 3
- [Ceftazidime](https://trialight.com/data/asset/ceftazidime-26aab43b-d019-49e2-8652-af26e1e98cc0.md) Phase 2
- Ceftazidime sodium Phase 2
- Ceftobiprole medocaril free acid Phase 3
- Ceftobiprole medocaril sodium Phase 3
- Ceftolozane Phase 2
- [Chlorhexidine](https://trialight.com/data/asset/chlorhexidine-73810300-e838-4872-8cbd-4e84000f38de.md) Phase 3
- [Ciprofloxacin](https://trialight.com/data/asset/ciprofloxacin-8dbb4fad-883a-4e58-8501-5887c084b0ef.md) Phase 3
- [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2

### Other linked drugs (8)

- Amikacin
- Cloxacillin
- Cloxacillin sodium
- [Itraconazole](https://trialight.com/data/asset/itraconazole-c6f2473e-393a-44a9-8969-8d501b15ef65.md)
- [Meropenem](https://trialight.com/data/asset/meropenem-a90880e5-37b0-473b-bf12-d5f0de7894c2.md)
- [Moxifloxacin](https://trialight.com/data/asset/moxifloxacin-17fc41bd-6b29-4dda-a755-554e6ce94ccc.md)
- Piperacillin
- Teicoplanin

---

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