> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/neoplasm-of-esophagus-686857a5-1988-501d-b375-45b5c702ba62
> Record changed: 2026-10-13

# Neoplasm of esophagus

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

A neoplasm (disease) that involves the esophagus.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Neoplasm of esophagus

**Therapeutic area**

Oncology

### Alternative names (20)

- neoplasm of esophagus
- esophageal neoplasm
- esophageal neoplasms, benign and malignant
- esophageal tumor
- esophageal tumors
- esophageal tumour
- esophageal tumours
- esophagus neoplasm
- esophagus neoplasm (disease)
- esophagus tumor
- neoplasm of esophagus
- neoplasm of the esophagus
- neoplasm of the oesophagus
- oesophagus neoplasm
- oesophagus neoplasm (disease)
- oesophagus tumour
- tumor of esophagus
- tumor of the esophagus
- tumour of oesophagus
- tumour of the oesophagus

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Gastroenterology
- Oncology

## Identifiers

**MONDO ID**

MONDO:0021355

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021355)

**Parent condition**

MONDO:0003749

## Related records

### Broader conditions (11)

- Cancer or benign tumor
- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md)
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Esophageal disorder
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Upper digestive tract disorder

### Narrower conditions (29)

- Barrett adenocarcinoma
- Benign neoplasm of esophagus
- Carcinoma of esophagus
- Carcinoma of esophagus, salivary gland type
- [Esophageal adenocarcinoma](https://trialight.com/data/condition/esophageal-adenocarcinoma-4bf4a077-18f0-54cb-9a30-b8ea936afe32.md)
- Esophageal adenoid cystic carcinoma
- Esophageal adenosquamous carcinoma
- Esophageal basaloid carcinoma
- [Esophageal cancer](https://trialight.com/data/condition/esophageal-cancer-a3b5271c-e6d4-537b-8dfd-9391c60e2af2.md)
- Esophageal granular cell tumor
- Esophageal lipoma
- Esophageal melanoma
- Esophageal neuroendocrine tumor
- Esophageal small cell neuroendocrine carcinoma
- [Esophageal squamous cell carcinoma](https://trialight.com/data/condition/esophageal-squamous-cell-carcinoma-c10bd9c9-02f9-5805-8008-b021f4604e7a.md)
- Esophagus carcinoma in situ
- Esophagus leiomyoma
- Esophagus leiomyosarcoma
- Esophagus liposarcoma
- Esophagus lymphoma

### Trials (1,828)

- "Less-is-more in Barrett-surveillance" Care Evaluation of Barrett's Patients With Low-Risk in Whom Endoscopic Surveillance is Stopped. The BLISS Project.
- \[68Ga\]Ga-ABY-025 PET for Quantification of HER2-status in Solid Tumors
- 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors
- 18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer
- 18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer
- 2D-radiotherapy in Palliation of Advanced Esophageal Cancer
- 3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction
- 4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies
- 4D FDG PET in Esophageal Cancer
- 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
- 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)
- 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
- 99m Tc-3PRGD2 SPECT/CT Imaging in the Diagnosis of Lymph Node Metastasis of Esophageal Carcinoma
- 99mTc-3PRGD2 SPECT/CT in Esophagus Cancer Patients
- A Beta-only IL-2 ImmunoTherapY Study
- A Biomarker-driven Therapeutic Strategy for Esophageal Cancer Chemoradiotherapy in Patients With Resectable Adenocarcinoma of the ESophagus and Esophagogastric Junction
- A Clinical Research of CAR T Cells Targeting EpCAM Positive Cancer
- A Clinical Study Of Camrelizumab With Or Without Radiotherapy In The Treatment Of Esophageal Cancer
- A Clinical Study of Non-curative Resection Plus Radiotherapy After Endoscopic ESD for Superficial Esophageal Squamous Cell Carcinoma
- A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer

### Drugs in development (10)

- [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 2
- Camrelizumab Phase 3
- [Cetuximab](https://trialight.com/data/asset/cetuximab-a1f8c65c-bae1-4b77-9491-dca37aeeaa3c.md) Phase 3
- [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 3
- [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 3
- [Fluorouracil](https://trialight.com/data/asset/fluorouracil-f8444d73-5c73-4f35-aa71-67d578277450.md) Phase 3
- [Paclitaxel](https://trialight.com/data/asset/paclitaxel-889db92c-df97-46a6-bf1c-74974a87fa75.md) Phase 3
- [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md) Phase 3
- [Tegafur](https://trialight.com/data/asset/tegafur-373c07a7-2961-4c06-af1a-16fedfad4fd1.md) Phase 3
- Uracil Phase 2

### Other linked drugs (3)

- [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md)
- Povidone-iodine
- [Zolbetuximab](https://trialight.com/data/asset/zolbetuximab-93fd9fa2-039b-41eb-a488-43bca0e39a5b.md)

---

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