> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/nasopharyngeal-carcinoma-9ead4a97-f794-5dda-b62e-20f8ca202f89
> Record changed: 2026-10-13

# Nasopharyngeal carcinoma

Therapeutic area

Oncology

Rare disease

Yes

## Definition and classification

**Definition**

A carcinoma arising from the nasopharyngeal epithelium. It includes the following types: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma (differentiated and undifferentiated), basaloid squamous cell carcinoma, and papillary adenocarcinoma.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Nasopharyngeal carcinoma

**Therapeutic area**

Oncology

### Alternative names (29)

- nasopharyngeal carcinoma
- cancer of nasopharynx
- cancer of the nasopharynx
- malignant nasopharyngeal tumor
- malignant nasopharyngeal tumour
- malignant neoplasm of anterior wall of nasopharynx
- malignant neoplasm of lateral wall of nasopharynx
- malignant neoplasm of nasopharyngeal wall
- malignant neoplasm of nasopharynx
- malignant neoplasm of nasopharynx (disorder) \[ambiguous\]
- malignant neoplasm of other specified sites of nasopharynx
- malignant neoplasm of posterior wall of nasopharynx
- malignant neoplasm of roof of nasopharynx
- malignant neoplasm of superior wall of nasopharynx
- malignant tumor of anterior wall of nasopharynx
- malignant tumor of lateral wall of nasopharynx
- malignant tumor of posterior wall of nasopharynx
- malignant tumour of anterior wall of nasopharynx
- malignant tumour of lateral wall of nasopharynx
- malignant tumour of posterior wall of nasopharynx
- nasopharyngeal cancer
- nasopharyngeal throat cancer
- primary malignant neoplasm of anterior wall of nasopharynx
- NPC
- carcinoma of nasopharynx

And 4 more, listed on the interactive page.

## Clinical profile

**Disease mechanisms**

- Acquired

**Severity**

Severe

### All therapeutic areas (3)

- Gastroenterology
- Oncology
- Pulmonology

## Identifiers

**MONDO ID**

MONDO:0015459

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015459)

**Parent condition**

MONDO:0002038

## Related records

### Broader conditions (37)

- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Cancer or benign tumor
- [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md)
- Carcinoma of pharynx
- Digestive system cancer
- Digestive system carcinoma
- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md)
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Disorder of pharynx
- [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md)
- Epstein-Barr virus-associated carcinoma
- Epstein-Barr virus-related tumor
- [Head and neck cancer](https://trialight.com/data/condition/head-and-neck-cancer-3a2645b9-a3db-5103-b6f8-5d2ec40c5339.md)
- [Head and neck carcinoma](https://trialight.com/data/condition/head-and-neck-carcinoma-15d11e2c-18dd-5089-9c7b-487ae515e69c.md)
- [Head and neck neoplasm](https://trialight.com/data/condition/head-and-neck-neoplasm-6436d68c-825f-5a7a-bb29-99e9ae9e009a.md)
- Human disease

### Narrower conditions (2)

- Carcinoma in situ of nasopharynx
- Undifferentiated carcinoma of nasopharynx

### Trials (747)

- "Xijiang Project" Screening Cohort for NPC
- \[212Pb\]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers
- 18F-FDG PET/CT Guided Reduced-dose Radiotherapy for Nasopharyngeal Carcinoma
- 18F-FMISO PET Guided Dose Escalation in Nasopharyngeal Carcinoma - a Feasibility and Planning Study
- 3DV+TPS Software Outlines the Radiotherapy of Nasopharyngeal Carcinoma
- 40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma
- 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)
- 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
- A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Nasopharyngeal Carcinoma.
- A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
- A Clinical Study of Hetrombopag for Prevention of Thrombocytopenia Induced by Gemcitabine Plus Cisplatin in the Treatment of Nasopharyngeal Carcinoma
- A Clinical Study to Evaluate the Safety and Tolerability of JS001sc in Advanced Nasopharyngeal Carcinoma
- A Clinical Trial of Chemotherapy With Lobaplatin and 5-FU in Recurrent Local or Distant Advanced NPC.
- A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.).
- A Deep Learning Model for Diagnosing Lymph Node Metastasis in Nasopharyngeal Carcinoma(NPC)
- A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy
- A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis
- A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)
- A Multi-center, Randomized, Double-blind, Phase III Clinical Trial of Leucogen Versus Placebo on Leukocyte and Platelet Whole-course Management Assisted by PFLL Chemotherapy in the Treatment of Stage IV, Recurrent or Metastatic NPC
- A Multicenter Randomized Controlled Clinical Study on the Treatment of T3N1M0 High Risk Nasopharyngeal Carcinoma With or Without Induction Chemotherapy Before Concurrent Radiotherapy and Chemotherapy

### Approved drugs (1)

- [Toripalimab](https://trialight.com/data/asset/toripalimab-92e6b353-a6c4-4e1e-a99f-559038ba7177.md)

### Drugs in development (73)

- [Adebrelimab](https://trialight.com/data/asset/adebrelimab-047820dd-1777-483d-90ab-dd5fc86f78f6.md) Phase 2
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 2
- Atorvastatin Phase 2
- [Benmelstobart](https://trialight.com/data/asset/benmelstobart-2bff71aa-d2ac-4a5a-9949-c935954a2314.md) Phase 2
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2
- Bortezomib D-mannitol Phase 2
- Cabozantinib S-malate Phase 2
- [Cadonilimab](https://trialight.com/data/asset/cadonilimab-3970701f-ffc8-4027-a97b-4e6c913803e6.md) Phase 3
- Camrelizumab Phase 3
- [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 3
- [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3
- [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2
- Catequentinib hydrochloride Phase 2
- [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 3
- [Cetuximab](https://trialight.com/data/asset/cetuximab-a1f8c65c-bae1-4b77-9491-dca37aeeaa3c.md) Phase 3
- [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 3
- CM-4307 Phase 1
- [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Early phase 1
- [Dalpiciclib](https://trialight.com/data/asset/dalpiciclib-2001da9e-4c75-4a18-ae80-97f8c567dba5.md) Phase 2
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 2

### Other linked drugs (9)

- APG-1387
- Decitabine
- Erlotinib hydrochloride
- [Lotilaner](https://trialight.com/data/asset/lotilaner-93e7b35f-f1c9-407a-9965-0594b8eb6795.md)
- MK-2206
- Oxycodone
- Pevonedistat
- Seliciclib
- [Tocilizumab](https://trialight.com/data/asset/tocilizumab-58fcf741-84ea-43ec-ab1b-8fc8d306b59d.md)

---

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