> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/myositis-disease-9eae0a90-6131-52a2-b0a4-c5271d6f2554
> Record changed: 2026-11-04

# Myositis disease

Therapeutic area

Neuromuscular Disease

Rare disease

No

## Definition and classification

**Definition**

An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Myositis disease

**Therapeutic area**

Neuromuscular Disease

### Alternative names (4)

- myositis disease
- inflammation of muscle tissue
- inflammatory disorder of muscle (disorder)
- muscle tissue inflammation

## Clinical profile

**Disease mechanisms**

- Inflammatory

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021167)

**Severity**

Severe

### All therapeutic areas (2)

- Neuromuscular Disease
- Rheumatology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021167)

## Identifiers

**MONDO ID**

MONDO:0021167

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021167)

**Parent condition**

MONDO:0005336

## Related records

### Broader conditions (9)

- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Human disease
- Inflammatory disease
- Muscle tissue disorder
- [Musculoskeletal system disorder](https://trialight.com/data/condition/musculoskeletal-system-disorder-16f6e157-12a0-54ee-9e24-377731f344a5.md)
- Myopathy
- Skeletal muscle disorder

### Narrower conditions (56)

- Achilles bursitis
- [Acquired idiopathic inflammatory myopathy](https://trialight.com/data/condition/acquired-idiopathic-inflammatory-myopathy-18d0eb22-6fbd-59d0-889d-3ac4266a57f2.md)
- Adermatopathic dermatomyositis
- Adult dermatomyositis
- Amyopathic dermatomyositis
- Anti-MDA5 dermatomyositis
- Anti-Mi2 dermatomyositis
- Anti-NXP2 dermatomyositis
- Anti-SAE dermatomyositis
- Anti-TIF1 dermatomyositis
- Antisynthetase syndrome
- Bacterial myositis
- Bicipital tenosynovitis
- Calcific tendinitis
- Childhood-onset autosomal recessive myopathy with external ophthalmoplegia
- Classical dermatomyositis
- Clinically amyopathic dermatomyositis
- [Dermatomyositis](https://trialight.com/data/condition/dermatomyositis-363b640a-406f-523a-ae6a-6f4abe2008fb.md)
- Eosinophilic fasciitis
- Familial idiopathic inflammatory myopathy

### Trials (221)

- A Case-control Study to Assess Risk of Coronary Heart Disease in Idiopathic Inflammatory Myopathy
- A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases
- A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
- A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases
- A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases
- A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases
- [A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease](https://trialight.com/data/trial/a-phase-1-study-of-ft819-in-b-cell-mediated-autoimmune-6b8b0d2c-15f0-4af3-a304-bbce1760f628.md)
- [A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease](https://trialight.com/data/trial/a-phase-1-study-of-prulacabtagene-leucel-prula-cel-formerly-0aebce17-d67c-419f-b24a-9fff94392a5e.md)
- A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
- A Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermatomyositis (DM) or Anti-synthetase Inflammatory Myositis (ASIM)
- A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis
- A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
- A Study of Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP)
- A Study of AZD0120 in Autoimmune Diseases
- A Study of BEN301 Injection in theTreatment of Autoimmune Diseases
- A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases
- [A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)](https://trialight.com/data/trial/a-study-of-cc-97540-cd-19-targeted-nex-t-car-t-cells-in-8290d9b7-24da-4ac1-a5b0-156c725633bb.md)
- A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases
- A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)
- [A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases](https://trialight.com/data/trial/a-study-of-healthy-donor-cd19-targeted-allogeneic-car-t-b1d04a74-424e-4293-b03a-d260c48aba9d.md)

### Drugs in development (21)

- Aldesleukin Phase 2
- Antilymphocyte immunoglobulin (horse) Phase 1
- [Baricitinib](https://trialight.com/data/asset/baricitinib-dde0cdc5-8f75-41b1-bc92-b187471c63df.md) Phase 2
- [Belimumab](https://trialight.com/data/asset/belimumab-a26501e5-b55d-4ccb-a721-a60267831e12.md) Phase 2
- [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 1
- [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 1
- Cyclosporine Phase 2
- Dantrolene Phase 2
- Dazukibart Phase 3
- [Empasiprubart](https://trialight.com/data/asset/empasiprubart-fff1146e-9b4c-4285-8e1c-6fd358cd925d.md) Phase 2
- FAPI GA-68 Early phase 1
- Infliximab Phase 2
- Nipocalimab Phase 2
- Omega-3-acid ethyl esters Phase 2
- Plamotamab Phase 1
- [Prednisone](https://trialight.com/data/asset/prednisone-a5a99f90-5fbe-45c2-a625-34ba78735da6.md) Phase 2
- Rapcabtagene autoleucel Phase 2
- [Rituximab](https://trialight.com/data/asset/rituximab-3fb73477-f618-414e-aa0a-9ccba4d6da3f.md) Phase 2
- Sodium thiosulfate Phase 2
- [Telitacicept](https://trialight.com/data/asset/telitacicept-29fd6e0f-15b8-4b2e-966c-3ba8f073e93b.md) Phase 2

### Other linked drugs (1)

- Corticotropin

---

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