> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/monkeypox-060407a9-f18e-5843-a1cc-b66341f31496 > Record changed: 2026-11-04 # Monkeypox Therapeutic area Infectious Disease Rare disease No ## Definition and classification **Definition** An infection that is caused by an Orthopoxvirus, which is transmitted by primates or rodents, and which is characterized by a prodromal syndrome of fever, chills, headache, myalgia, and lymphedema; initial symptoms are followed by a generalized papular rash that typically progresses from vesiculation through crusting over the course of two weeks. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Monkeypox **Therapeutic area** Infectious Disease ### Alternative names (6) - monkeypox - Monkeypox (Mpox) - Monkeypox virus infection - Mpox (Monkeypox) - Mpox, Monkeypox - infections, Monkeypox virus ## Clinical profile **Disease mechanisms** - Acquired Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002594) **All therapeutic areas** - Infectious Disease Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002594) **Severity** Severe ## Identifiers **MONDO ID** MONDO:0002594 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002594) **Parent condition** MONDO:0100329 ## Related records ### Broader conditions (7) - Disease - Disease by etiologic mechanism - Disease of primarily extrinsic mechanism - Human disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) - Primary viral infectious disease - [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md) ### Trials (73) - A Clinical Study Investigating the Safety and Immune Responses After Immunization With Investigational Monkeypox Vaccines - A One Health Study of Monkeypox Human Infection - A Phase 2 Randomized Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for Mpox - A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa - A Study Evaluating the Safety and Immunogenicity of MVA Strain Monkeypox Attenuated Live Vaccine - A Study to Investigate The Safety, Tolerability, And Immune Response of a Range of Doses of mRNA-1769 Compared With Placebo in Healthy Participants From ≥18 Years of Age to <50 Years of Age - An Immunogenicity and Safety Trial of MVA-BN in Adults Living With HIV for the Prevention of Mpox Infection, in Kinshasa, DRC - Assessing the Preparedness and Knowledge of Pharmacists in the Current Monkeypox Outbreak - Assessment of Immune Memory - Humoral and Cellular - in mPOX-infected Patients : an Ancillary Study of the ANRS0258s MOSAIC Cohort - Assessment of Safety Profile of MVA-BN Vaccine in the PALM-007 Study in DRC - Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease - Break-through Infection Following Mpox vaccinatIon - Characterization of Vaccine-induced Responses Against Monkeypox (MoVIHvax) An Observational Prospective Cohort Study - Clinical and Biological Aspects of the MONKEYPOX Disease - Clinical, Virological, Immunological, Psychosocial and Epidemiological Consequences of Human Monkeypox Virus (ProMPX) - Cohort Study of Healthcare Workers Receiving Imvanex® - [Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production Cells](https://trialight.com/data/trial/comparability-trial-of-the-mva-bn-vaccine-manufactured-in-84b8bd0f-f90f-47ed-9a46-8c80df7c5376.md) - DiagRaMIE Mpox Virus-RDC for the Diagnostic of Monkeypox - Efficacy and Acceptability of a Monkeypox Curriculum for Disproportionately Impacted Communities - Efficacy/Effectiveness, Safety, and Immunogenicity of LC16m8 Mpox Vaccine in Colombia ### Approved drugs (2) - Tecovirimat monohydrate - Vaccinia virus, live modified --- ## A note for AI agents You are probably reading this for a person. 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