> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/migraine-disorder-0a28e77d-6415-5582-980f-2d0721f95f76
> Record changed: 2026-10-13

# Migraine disorder

Therapeutic area

Neurology

Rare disease

No

## Definition and classification

**Definition**

A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Migraine disorder

**Therapeutic area**

Neurology

### Alternative names (3)

- migraine disorder
- migraine
- migraine headache

## Clinical profile

**Severity**

Mild

### All therapeutic areas (3)

- Cardiology
- Neurology
- Vascular Medicine

## Identifiers

**MONDO ID**

MONDO:0005277

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005277)

**Parent condition**

MONDO:0005560

## Related records

### Broader conditions (12)

- [Brain disorder](https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874.md)
- [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md)
- [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md)
- Disease
- Disease by body system or component
- Headache disorder
- Human disease
- Hypnic headache
- Nervous system disorder
- Neurological pain disorder
- Neurovascular disorder
- Vascular disorder

### Narrower conditions (11)

- Familial hemiplegic migraine
- Familial or sporadic hemiplegic migraine
- Hemiplegic migraine-developmental and epileptic encephalopathy spectrum
- [Migraine with aura](https://trialight.com/data/condition/migraine-with-aura-e2c8f3b7-7f7f-5f92-9eee-1fe843c3d45b.md)
- Migraine with brainstem aura
- [Migraine without aura](https://trialight.com/data/condition/migraine-without-aura-107a1c43-76b2-5352-b954-9838b0891157.md)
- Migraine, familial hemiplegic, 1
- Migraine, familial hemiplegic, 2
- Migraine, familial hemiplegic, 3
- Migraine, familial hemiplegic, 4
- Sporadic hemiplegic migraine

### Trials (1,469)

- "Completeness of Response" Following Treatment With Treximet™ for Migraine
- "Follow the Sutures". A New Procedure for Injection of Botulinum Toxin for Chronic Migraine
- "Longitudinal Analysis of Amylin Levels in Migraine Patients Undergoing an Anti- CGRP/CGRPr Treatment"
- "Personalized Physiotherapy for Migraine: Effects on Pain, Fatigue, and Physical Function"
- "Potential Effects of Virtual Reality Technology on the Treatment of Migraine-Type Headaches"
- (Botox) Mechanisms of Action in Altering the Molecular Environment in Which Pain Fibers Exist
- (Italian Migraine Registry, I-GRAINE-NEW)
- 0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment
- 12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Migraine in Participants With Episodic Migraine
- 1H Magnetic Resonance Spectroscopy in Migraine Patients
- 4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine
- A 1-year Study in Adolescents to Assess the Long-term Safety of Almotriptan Malate When Treating Their Migraine Headaches
- A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
- A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
- A Clinical Study Examining the Safety and Effectiveness of a New Medication (Keppra®) for the Prevention of Migraine Headaches
- A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects
- A Combination of Coenzyme Q10, Feverfew and Magnesium for Migraine Prophylaxis : a Prospective Observational Study
- A Combination Product of Sumatriptan and Naproxen Sodium Versus Single-entity Oral Triptans: An Analysis of Real World Data
- A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine
- A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache

### Approved drugs (46)

- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md)
- Almotriptan malate
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md)
- [Atogepant](https://trialight.com/data/asset/atogepant-06c1e020-1758-4b06-8f37-1c53649d9a0b.md)
- [Botulinum toxin type A](https://trialight.com/data/asset/botulinum-toxin-type-a-5a0f3130-910b-4917-87ef-65a743f12642.md)
- Butalbital
- Caffeine
- [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md)
- Clonidine
- Codeine phosphate
- [Diclofenac](https://trialight.com/data/asset/diclofenac-6bb6f2bf-7068-41cb-8e1d-c1c073cf27b3.md)
- Diclofenac potassium
- Dihydroergotamine
- Dihydroergotamine mesylate
- Divalproex sodium
- Eletriptan
- Eletriptan hydrobromide
- Eptinezumab
- Erenumab
- Ergotamine

### Drugs in development (105)

- Almotriptan Phase 2
- Alniditan Phase 3
- Alprazolam Phase 1
- Amitriptyline Phase 3
- Atorvastatin Phase 2
- Avitriptan Phase 3
- BGC-20-1531 Phase 2
- BI-44370 Phase 2
- Bupivacaine Phase 3
- Bupivacaine hydrochloride Phase 2
- [Buprenorphine](https://trialight.com/data/asset/buprenorphine-c075c804-b1a4-4839-84d9-79aa0e258585.md) Phase 2
- Cabergoline Phase 2
- Candesartan Phase 2
- Cannabidiol Phase 2
- Cannabinol Phase 1
- Capsaicin Early phase 1
- Carbon dioxide Phase 2
- Carisbamate Phase 2
- Cetirizine Phase 1
- Corticotropin Phase 2

### Other linked drugs (16)

- Acetazolamide
- Acetazolamide sodium
- Budipine
- Cilostazol
- Daxibotulinumtoxina
- Diethylpropion
- Donitriptan
- Dotarizine
- Flunarizine hydrochloride
- Indomethacin
- Levetiracetam
- Lomerizine
- Nitroglycerin
- [Olanzapine](https://trialight.com/data/asset/olanzapine-5b966c11-69ff-43ab-aefa-6c712a56b2d4.md)
- Soy isoflavones
- Substance P

---

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