> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/methamphetamine-dependence-b0540c7c-c3c6-5935-8125-804fd4996afb
> Record changed: 2026-10-13

# Methamphetamine dependence

Rare disease

No

## Definition and classification

**Definition**

A drug dependence that is a psychological dependency on the regular use of methamphetamine.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Methamphetamine dependence

**Alternative names**

- methamphetamine dependence

## Clinical profile

**Severity**

Mild

## Identifiers

**MONDO ID**

MONDO:0005419

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005419)

**Parent condition**

MONDO:0005303

## Related records

### Broader conditions (7)

- Disease
- Disease by developmental or physiological process
- Drug dependence
- Human disease
- Psychiatric disorder
- Substance dependence
- [Substance-related disorder](https://trialight.com/data/condition/substance-related-disorder-9c15a305-edff-58d9-bcab-66e51bb69056.md)

### Trials (84)

- A Clinical Trial of Acamprosate for Treatment of Methamphetamine Addiction
- A Cognitive Behavioral Therapy-Based Text Messaging Intervention for Methamphetamine Dependence
- A Comparison of Paliperidone and Risperidone for Treatment of Patirnts With Methamphetamine-Associated Psychosis
- A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis
- A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence
- A Randomized, Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence
- A Trial of Long-Acting Injectable Risperidone in the Treatment of Methamphetamine Dependence
- ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals
- An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence
- An Study of Aripiprazole in the Treatment of Methamphetamine Dependence
- An Study of Paliperidone Extended-Release Tablets in the Treatment of Methamphetamine Dependence
- Aripiprazole for Methamphetamine Dependence: Double Blind Placebo Trial
- Buspirone as a Candidate Medication for Methamphetamine Abuse
- Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study
- Citicoline Treatment of Methamphetamine Dependence
- Clinical Efficacy of Atomoxetine for Methamphetamine Dependence
- Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence
- Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
- Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence
- Comparison of Methamphetamine-Dependent and Healthy Volunteers Using a Web-Enabled Cognitive Neuropsychological Evaluation System

### Drugs in development (44)

- Acamprosate Phase 1
- Acetylcysteine Phase 2
- [Aripiprazole](https://trialight.com/data/asset/aripiprazole-ca9997bd-e762-4bd5-ae57-3df4e68a30dd.md) Phase 1
- Atomoxetine Phase 1
- [Buprenorphine](https://trialight.com/data/asset/buprenorphine-c075c804-b1a4-4839-84d9-79aa0e258585.md) Phase 2
- Bupropion Phase 2
- Candesartan Phase 1
- [Citicoline](https://trialight.com/data/asset/citicoline-f5938bef-5da4-4d58-8885-c4ba9dd1cf3c.md) Phase 3
- Citicoline sodium Phase 3
- Devextinetug Phase 2
- Dextroamphetamine Phase 2
- Disulfiram Phase 1
- Duloxetine Phase 1
- Entacapone Early phase 1
- Haloperidol Phase 2
- Ibudilast Phase 2
- Lisdexamfetamine Phase 1
- Lobeline Phase 1
- Lorazepam Phase 2
- Mephedrone Phase 1

### Other linked drugs (2)

- Methamphetamine hydrochloride
- Paliperidone

---

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