> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/metastatic-melanoma-a7d9cd5e-6b12-5442-ba47-7839b5fda64e > Record changed: 2026-11-04 # Metastatic melanoma Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Metastatic melanoma **Therapeutic area** Oncology ### Alternative names (2) - metastatic melanoma - metastatic malignant melanoma ## Clinical profile **Disease mechanisms** - Developmental Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005191) **All therapeutic areas** - Oncology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005191) **Severity** Terminal ## Identifiers **MONDO ID** MONDO:0005191 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005191) **Parent condition** MONDO:0005105 ## Related records ### Broader conditions (11) - Cancer or benign tumor - Disease - Disease by developmental or physiological process - Disease by etiologic mechanism - Disorder of development or morphogenesis - Human disease - Melanocytic neoplasm - [Melanoma](https://trialight.com/data/condition/melanoma-457e9de6-dcd9-56fb-be48-0290fb4386ef.md) - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - Neurocristopathy ### Narrower conditions (1) - Ovarian melanoma ### Trials (377) - 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases - 7T MRI Scan for the Early Detection of Melanoma Brain Metastases - A CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and Nivolumab - A Clinical Study of the Safety and Activity of the Investigational Cell Therapy NEO-PTC-01 in Patients With Advanced Melanoma - A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma - A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors - A Novel Treatment for Metastatic Melanoma - A Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced Melanoma - A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies - A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors - A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma - A Phase 2 Study to Assess the Safety and Efficacy of IMO-2125 With 8 mg Ipilimumab in Patients With Metastatic Melanoma - A Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 Melanoma - A Phase I Study of ABT-888 in Combination With Temozolomide in Cancer Patients - A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Combination With Temozolomide in Patients With Advanced and/or Metastatic Melanoma - A Phase I/II Open-Label Study of Ipilimumab and GM-CSF Administered to Unresectable Stage IIIC and Stage IV Melanoma Patients - A Phase I/II Study of Dasatinib and Dacarbazine - A Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic Melanoma - A Pilot Study Using Short-Term Cultured Anti-Tumor Autologous Lymphocytes - A Prospective Observational Study on Targeted Therapy for Unresectable or Metastatic BRAFV600E Mutant Melanoma Patients ### Approved drugs (13) - Aldesleukin - Binimetinib - Cobimetinib fumarate - Dabrafenib mesylate - Dacarbazine - Encorafenib - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) - Lifileucel - [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md) - Peginterferon alfa-2B - [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md) - Trametinib dimethyl sulfoxide - Vemurafenib ### Drugs in development (145) - [Acetazolamide](https://trialight.com/data/asset/acetazolamide-a53ca950-beb6-4a09-9501-5e79acab15cc.md) Phase 1 - [Aflibercept](https://trialight.com/data/asset/aflibercept-6bb09e87-ca99-436b-8634-71b90510b8fb.md) Phase 3 - Arsenic trioxide Phase 1 - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 3 - [Autogene cevumeran](https://trialight.com/data/asset/autogene-cevumeran-eb4276fe-4301-43ae-889f-3f338e7e2485.md) Phase 2 - [Azacitidine](https://trialight.com/data/asset/azacitidine-4f3798ea-680c-4288-a367-118b7bfe411f.md) Phase 2 - Balstilimab Phase 3 - Bavunalimab Phase 1 - Belapectin Phase 1 - Bempegaldesleukin Phase 3 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - Bupropion Phase 1 - [Cabozantinib](https://trialight.com/data/asset/cabozantinib-e69f9fa7-bbbc-4e52-b0df-6073598de2a7.md) Phase 2 - [Caffeine](https://trialight.com/data/asset/caffeine-4062cceb-b322-4d67-b5b1-c5c5913c8897.md) Phase 1 - Calcitriol Phase 1 - [Camrelizumab](https://trialight.com/data/asset/camrelizumab-db95676a-3681-47ee-8647-408fc9391e28.md) Phase 3 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 1 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3 - CD24FC Phase 1 - CDX-1140 Phase 1 ### Other linked drugs (2) - Interferon alfa - Melphalan --- ## A note for AI agents You are probably reading this for a person. 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