> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/mesothelioma-49ad8bc3-59bf-506b-aa1a-b31c5d0f0e9d
> Record changed: 2026-10-13

# Mesothelioma

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Mesothelioma

**Therapeutic area**

Oncology

### Alternative names (2)

- mesothelioma
- mesothelioma

## Clinical profile

**All therapeutic areas**

- Oncology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0005065

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005065)

**Parent condition**

MONDO:0006856

## Related records

### Broader conditions (7)

- Cancer or benign tumor
- Disease
- Disease by etiologic mechanism
- Human disease
- Mesothelial neoplasm
- Neoplasm
- Neoplastic disease or syndrome

### Narrower conditions (31)

- Adenomatoid tumor
- Adenomatoid tumour of the peritoneum
- Benign mesothelioma
- Benign peritoneal mesothelioma
- Diffused pleural mesothelioma
- Epididymal adenomatoid tumor
- Fallopian tube adenomatoid tumor
- Localized pleural mesothelioma
- Lymphohistiocytoid mesothelioma
- Malignant biphasic mesothelioma
- Malignant epithelioid mesothelioma
- [Malignant mesothelioma](https://trialight.com/data/condition/malignant-mesothelioma-5e55096e-7573-5100-9df6-b4fdf036251d.md)
- Malignant pericardial mesothelioma
- Malignant peritoneal mesothelioma
- Malignant pleural mesothelioma
- Mesothelioma of the tunica vaginalis
- Ovarian malignant mesothelioma
- Peritoneal mesothelioma
- Peritoneal mesothelioma in situ
- Peritoneal multicystic mesothelioma

### Trials (294)

- 11C-Methionine PET/CT Imaging in Patients Affected by Malignant Pleural Mesothelioma (MPM)
- 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours
- 18F-Fibroblast Activation Protein Inhibitor (\[18F\]FAPI-74) PET Imaging for Cancer Detection
- 18F-FSPG PET/CT for Cancer Patients on Therapy
- A 2-part Phase 1/2 Open-label Trial on ODM-212
- A Clinical Study of Anetumab Ravtansine in Adults With Solid Tumors Who Have Been Treated in Previous Bayer-sponsored Anetumab Ravtansine Studies
- A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid Tumors
- A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549
- A Double Blind, Placebo Controlled, Randomized Phase II Study Evaluating Gemcitabine With or Without Ramucirumab , for II Line Treatment MPM
- A Feasibility Study Evaluating Surgery for Mesothelioma After Radiation Therapy Using Extensive Pleural Resection
- A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
- A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
- A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
- A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer
- A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors
- A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural Mesothelioma
- A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors
- A Phase I/II Study of First Line Vorinostat With Pemetrexed-cisplatin, in Patients With Malignant Pleural Mesothelioma
- A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy
- A Phase II Study of the Association of Glivec® Plus Gemzar® in Patients With Unresectable, Refractory, Malignant Mesothelioma

### Approved drugs (6)

- [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md)
- [Pemetrexed](https://trialight.com/data/asset/pemetrexed-2221859e-676b-4d76-97df-e11f3f9664a1.md)
- [Pemetrexed disodium](https://trialight.com/data/asset/pemetrexed-disodium-c80fe85f-320e-4817-87cb-0c8bbcbe8967.md)
- Pemetrexed disodium hemipentahydrate
- Pemetrexed monohydrate
- Pemetrexed tromethamine

### Drugs in development (107)

- [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 2
- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 1
- Aldesleukin Phase 1
- Amatuximab Phase 2
- Anetumab ravtansine Phase 2
- Antineoplaston A10 Phase 2
- [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 3
- [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 1
- Belinostat Phase 2
- Bemcentinib Phase 2
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 3
- Bintrafusp alfa Phase 2
- BIW-8962 Phase 1
- Bortezomib D-mannitol Phase 2
- Bosutinib Phase 1
- [Cadonilimab](https://trialight.com/data/asset/cadonilimab-3970701f-ffc8-4027-a97b-4e6c913803e6.md) Phase 2
- [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 2
- [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3
- [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2
- Cediranib maleate Phase 2

### Other linked drugs (1)

- CBP-501

---

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