> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/meningioma-5ed57dc9-a477-5890-89ce-dc398e272670
> Record changed: 2026-11-04

# Meningioma

Therapeutic area

Neurology

Rare disease

Yes

## Definition and classification

**Definition**

A generally slow growing tumor attached to the dura mater. It is composed of neoplastic meningothelial (arachnoidal) cells. It typically occurs in adults, often women and it has a wide range of histopathological appearances. Of the various subtypes, meningothelial, fibrous and transitional meningiomas are the most common. Most meningiomas are WHO grade I tumors, and some are WHO grade II or III tumors. Most subtypes share a common clinical behavior, although some subtypes are more likely to recur and follow a more aggressive clinical course. (Adapted from WHO)

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Meningioma

**Therapeutic area**

Neurology

### Alternative names (4)

- meningioma
- meningioma (disease)
- meningothelial cell tumour
- primary meningeal tumour

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Neurology
- Oncology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0016642)

## Identifiers

**MONDO ID**

MONDO:0016642

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0016642)

**Parent condition**

MONDO:0016743

## Related records

### Broader conditions (12)

- Cancer or benign tumor
- [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md)
- Central nervous system neoplasm
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Human disease
- [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md)
- Neoplastic disease or syndrome
- [Nervous system disorder](https://trialight.com/data/condition/nervous-system-disorder-541eb3ed-9656-574d-babf-28139b060a42.md)
- Nervous system neoplasm
- Tumor of meninges

### Narrower conditions (83)

- Adult leptomeningeal melanoma
- Adult papillary meningioma
- Anaplastic meningioma
- Angiomatous meningioma
- Anterior cranial fossa meningioma
- Anterior foramen magnum meningioma
- Anterior optic tract meningioma
- Benign meningioma
- Bilateral meningioma of optic nerve
- Brainstem intraparenchymal clear cell meningioma
- Cavernous sinus meningioma
- Cerebellopontine angle meningioma
- Cerebral convexity meningioma
- Cerebral falx meningioma
- Cerebral meningioma
- Cervical spinal canal and spinal cord meningioma
- Childhood brain meningioma
- Chordoid meningioma
- Choroid plexus meningioma
- Clear cell meningioma

### Trials (250)

- 177Lu-DOTATATE for Recurrent Meningioma
- 3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features
- 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.
- 68Ga-DOTA-TOC PET/CT in Imaging Participants With Neuroendocrine Tumors
- 68Ga-Dotatate PET and MRI Guided Radiation Dose Escalation for High Risk Meningioma
- 9-ING-41 in Pediatric Patients With Refractory Malignancies.
- A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
- A Dual-targeting Tracer TATE-RGD for the Diagnosis of SSTR- and RGD- Positive Tumors
- A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
- A Phase III Study of SYHA1813 for Recurrent or Progressive High-Grade Meningiomas
- A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma
- A Study of ONC201 for Refractory Meningioma
- A Study of the Boron Neutron Capture Therapy (BNCT) Using B10 L-BPA in Recurrent Meningioma
- A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
- A Trial of Increased Dose Intensity Modulated Proton Therapy (IMPT) for High-Grade Meningiomas
- A Trial of Pembrolizumab for Refractory Atypical and Anaplastic Meningioma
- Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors
- Abemaciclib in Newly Diagnosed Meningioma Patients
- Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy
- Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

### Drugs in development (49)

- [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 2
- Aldesleukin Phase 1
- [Alpelisib](https://trialight.com/data/asset/alpelisib-0b0ae0f7-4313-42ef-bbbe-3280ed5ea15c.md) Phase 1
- Aminolevulinic acid hydrochloride Phase 3
- Antineoplaston A10 Phase 2
- AR-42 Phase 2
- [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 1
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2
- Brigatinib Phase 2
- [Cabozantinib](https://trialight.com/data/asset/cabozantinib-e69f9fa7-bbbc-4e52-b0df-6073598de2a7.md) Phase 2
- [Capivasertib](https://trialight.com/data/asset/capivasertib-935ebe6a-a1c8-413b-8259-07e301a25a61.md) Phase 2
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 2
- Dordaviprone Phase 1
- Edotreotide Phase 2
- Edotreotide gallium GA-68 Phase 2
- Erlotinib hydrochloride Phase 1
- [Everolimus](https://trialight.com/data/asset/everolimus-0edf09a9-672d-4f9a-9e34-21ab083a92a4.md) Phase 2
- Gefitinib Phase 2
- GSK-2256098 Phase 2
- Hydroxyurea Phase 2

### Other linked drugs (2)

- [Rivoceranib mesylate](https://trialight.com/data/asset/rivoceranib-mesylate-e3d23ea8-6bde-4278-b83d-13515b955293.md)
- [Sintilimab](https://trialight.com/data/asset/sintilimab-e2618eaf-967e-401c-aed4-7546875a6d3e.md)

---

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