> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/malignant-mesothelioma-5e55096e-7573-5100-9df6-b4fdf036251d > Record changed: 2026-10-13 # Malignant mesothelioma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A malignant neoplasm of the pleura or peritoneum, arising from mesothelial cells. It is associated with exposure to asbestos. **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Malignant mesothelioma **Therapeutic area** Oncology ### Alternative names (18) - malignant mesothelioma - malignant mesothelial tumor - malignant mesothelial tumour - malignant mesothelioma - malignant mesothelioma (disease) - malignant neoplasm of mesothelium - malignant neoplasm of the mesothelium - malignant tumor of mesothelium - malignant tumor of the mesothelium - malignant tumour of mesothelium - malignant tumour of the mesothelium - mesothelioma, malignant - mesothelioma, somatic - advanced malignant mesothelioma - asbestos-related malignant mesothelioma - diffuse malignant mesothelioma - malignant mesothelial neoplasm - MESOM ## Clinical profile **All therapeutic areas** - Oncology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0006292 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006292) **Parent condition** MONDO:0004992 ## Related records ### Broader conditions (9) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Disease - Disease by etiologic mechanism - Human disease - Mesothelial neoplasm - [Mesothelioma](https://trialight.com/data/condition/mesothelioma-49ad8bc3-59bf-506b-aa1a-b31c5d0f0e9d.md) - Neoplasm - Neoplastic disease or syndrome ### Narrower conditions (15) - Diffused pleural mesothelioma - Localized pleural mesothelioma - Lymphohistiocytoid mesothelioma - Malignant biphasic mesothelioma - Malignant epithelioid mesothelioma - Malignant pericardial mesothelioma - Malignant peritoneal mesothelioma - Malignant pleural mesothelioma - Mesothelioma of the tunica vaginalis - Ovarian malignant mesothelioma - Pleural biphasic mesothelioma - Pleural epithelioid mesothelioma - Pleural mesothelioma in situ - Pleural sarcomatoid mesothelioma - Sarcomatoid mesothelioma ### Trials (327) - ......SMARTEST Trial...... - 11C-Methionine PET/CT Imaging in Patients Affected by Malignant Pleural Mesothelioma (MPM) - 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors - A Beta-only IL-2 ImmunoTherapY Study - A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesothelioma - A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma - A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia - A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease - A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma - A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer - A Phase I/II Study of First Line Vorinostat With Pemetrexed-cisplatin, in Patients With Malignant Pleural Mesothelioma - A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors - A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy - A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers - A Phase II Study of PF-03446962 in Patients With Advanced Malignant Pleural Mesothelioma - A Pilot Study to Explore the Role of Gut Flora in Metastatic Mesothelioma - A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma - A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors - A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma - A Study of Atezolizumab in Unresectable or Advaced Malignant Pleural Mesothelioma ### Approved drugs (3) - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) - [Pemetrexed disodium](https://trialight.com/data/asset/pemetrexed-disodium-c80fe85f-320e-4817-87cb-0c8bbcbe8967.md) - Pemetrexed monohydrate ### Drugs in development (9) - [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 2 - [Brentuximab vedotin](https://trialight.com/data/asset/brentuximab-vedotin-b112eac4-7573-41dc-af6c-6c9212132a79.md) Phase 2 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 2 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2 - [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md) Phase 2 - [Pemetrexed](https://trialight.com/data/asset/pemetrexed-2221859e-676b-4d76-97df-e11f3f9664a1.md) Phase 2 - [Ramucirumab](https://trialight.com/data/asset/ramucirumab-5b87de8e-9f6e-425a-af38-bdf4267e4130.md) Phase 2 - [Tremelimumab](https://trialight.com/data/asset/tremelimumab-24e58585-33c8-4837-b098-dae8de9e4d79.md) Phase 3 - VS-5584 Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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