Malignant glioma
Therapeutic area
Oncology
Rare disease
No
- Definition
- A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Malignant glioma
- Therapeutic area
- Oncology
- malignant glioma
- Advanced Malignant Glioma
- CNS Primary Tumor, NOS (Malignant Glioma)
- Glial Cell Tumors
- glial cell tumour
- glioma, malignant
- high grade glioma
- High Grade Glioma (HGG)
- High Grade Glioma (III or IV)
- high-grade glioma
- High-Grade Glioma (HGG)
- High-Grade Glioma (WHO III-IV)
- malignant glial neoplasm
- malignant glial tumor
- malignant glial tumour
- Malignant Glioma (WHO Grade III or IV)
- malignant neuroglial neoplasm
- malignant neuroglial tumor
- malignant neuroglial tumour
- Newly Diagnosed High Grade Glioma
- Newly Diagnosed High Grade Glioma (HGG)
- Newly Diagnosed High-Grade Glioma
- Recurrent High Grade Glioma
- Recurrent High-Grade Glioma
- Recurrent Malignant Glioma
And 4 more, listed on the interactive page.
- Severity
- Severe
- Neurology
- Oncology
Sources for recorded values
- MONDO ID
- MONDO:0100342
- Parent condition
- MONDO:0002714
Related records
Broader conditions (17)
- Cancer
- Cancer or benign tumor
- Central nervous system cancer
- Central nervous system disorder
- Central nervous system neoplasm
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Glioma
- High grade malignant neoplasm
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Nervous system cancer
- Nervous system disorder
- Nervous system neoplasm
- Neuroepithelial neoplasm
Narrower conditions (99)
- Adult anaplastic ependymoma
- Adult brain ependymoma
- Adult brainstem astrocytoma
- Adult brainstem glioma
- Adult brainstem gliosarcoma
- Adult brainstem mixed glioma
- Adult glioblastoma
- Adult malignant schwannoma
- Adult oligodendroglioma
- Adult spinal cord ependymoma
- Adult spinal cord glioblastoma
- Anaplastic astrocytoma
- Anaplastic ependymoma
- Anaplastic oligoastrocytoma
- Anaplastic oligodendroglioma
- Astrocytoma, IDH-mutant, grade 2
- Astrocytoma, IDH-mutant, grade 3
- Astrocytoma, IDH-mutant, grade 4
- Brain glioblastoma
- Brain glioma
Trials (392)
- 131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma
- 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy
- 18F-DOPA-PET in Planning Surgery in Patients With Gliomas
- 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy
- 18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas
- 18F-Fluciclovine PET-MRI in High-grade Glioma
- 5-Aminolevulinic Acid (5-ALA) GliolanĀ®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas
- 5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor
- 68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma
- 9-ING-41 in Patients With Advanced Cancers
- A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or Progressive High-grade Glioma
- A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
- A Living Tissue Bank of Patient-Derived Organoids From Glioma Tumors
- A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas
- A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial
- A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
- A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.
- A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
- A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma
- A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
Approved drugs (3)
- Aminolevulinic acid hydrochloride
- Carmustine
- Temozolomide
Drugs in development (240)
- 6-O-benzylguanine Phase 2
- Abacavir Phase 1
- Abemaciclib Early phase 1
- AC-480 Phase 1
- Acetaminophen Phase 2
- ACT-001 Phase 2
- Afatinib Phase 2
- Aflibercept Phase 1
- Aglatimagene besadenovec Phase 1
- Alanine Early phase 1
- Alanosine Phase 1
- Aldesleukin Phase 1
- Alisertib Phase 1
- Alisertib sodium Phase 1
- AMG-404 Phase 1
- Amino acids Phase 2
- Aminolevulinic acid Phase 1
- ANG1005 Phase 1
- Antineoplaston A10 Phase 2
- Armodafinil Phase 2
Other linked drugs (5)
- Alovudine F-18
- Busulfan
- Lacosamide
- MAB-425
- Rivaroxaban