> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/male-reproductive-organ-cancer-842ea224-90be-5da5-8edd-9b6a8bc0f53e > Record changed: 2026-11-04 # Male reproductive organ cancer Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** A primary or metastatic malignant neoplasm involving the male reproductive system. Representative examples include prostate carcinoma, penile carcinoma, testicular seminoma, and testicular embryonal carcinoma. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Male reproductive organ cancer **Therapeutic area** Oncology ### Alternative names (24) - male reproductive organ cancer - cancer of male reproductive organ - Male Genital Cancer - malignant male reproductive organ neoplasm - malignant Male reproductive system neoplasm - malignant Male reproductive system tumor - malignant Male reproductive system tumour - malignant neoplasm of male genital organ, site unspecified - malignant neoplasm of male reproductive organ - malignant neoplasm of Male reproductive system - malignant neoplasm of the Male reproductive system - malignant tumor of male genital organ - malignant tumor of Male reproductive system - malignant tumor of the Male reproductive system - malignant tumour of male genital organ - malignant tumour of Male reproductive system - malignant tumour of the Male reproductive system - Recurrent Malignant Male Reproductive System Neoplasm - Refractory Malignant Male Reproductive System Neoplasm - male genital neoplasm - male reproductive system neoplasm - neoplasm of male genital organ - tumor of male reproductive system - tumour of male reproductive system ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Oncology - Reproductive Health Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005836) ## Identifiers **MONDO ID** MONDO:0005836 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005836) **Parent condition** MONDO:0002149 ## Related records ### Broader conditions (13) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - [Male reproductive system disorder](https://trialight.com/data/condition/male-reproductive-system-disorder-106dc445-bbb1-58aa-b02a-5e216e8b0d30.md) - Male reproductive system neoplasm - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - Reproductive system cancer - Reproductive system disorder - Reproductive system neoplasm ### Narrower conditions (113) - Acinar prostate adenocarcinoma, foamy gland variant - Acinar prostate adenocarcinoma, signet ring variant - Acinar prostate mucinous adenocarcinoma - Adenosquamous prostate carcinoma - Basaloid carcinoma of the penis - Carcinoma of Cowper glands - Castration-resistant prostate carcinoma - Childhood embryonal testis carcinoma - Childhood testicular choriocarcinoma - Childhood testicular mixed embryonal carcinoma and teratoma - Childhood testicular mixed germ cell cancer - Choriocarcinoma of testis - Cribriform variant testicular seminoma - Enteric pattern testicular yolk sac tumor - Epididymal adenocarcinoma - Epididymis cancer - Familial prostate carcinoma - Glans penis cancer - Grade III prostatic intraepithelial neoplasia - Hormone-resistant prostate carcinoma ### Trials (40) - \[Ac-225\]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate Cancer - 177Lu-PSMA-R2 in Patients With PSMA Positive Progressive, Metastatic, Castration Resistant Prostate Cancer - 18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer - 68Ga-PSMA-R2 in Patients With Biochemical Relapse (BR) and Metastatic Prostate Cancer (mPCa) - A JNJ-56021927 (ARN-509; Apalutamide) QT/QTc Study - A Phase 3 Study of \[177Lu\]Ludotadipep for Metastatic Castration-Resistant Prostate Cancer - A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts - A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer - A Study of Ixabepilone Before Surgery for High-Risk Localized Prostate Cancer - A Study of MK4827 in Participants With Advanced Solid Tumors or Hematologic Malignancies (MK-4827-001 AM8) - CATCH-R: A Rollover Study to Provide Continued Access to Rucaparib - Efficacy and Safety Study of TOOKAD® Soluble for Localised Prostate Cancer Compared to Active Surveillance. - Efficacy,Safety and Quality of Life After TOOKAD® Soluble VTP for Localized Prostate Cancer - Evaluation of Efficacy of TOOKAD® (VTP) Versus Active Surveillance for Intermediate Risk Localized Prostate Cancer - Evaluation of Length and Quality of Prostate Biopsies Taken by a New Biopsy Needle - EVOLUTION: 177Lu-PSMA Therapy Versus 177Lu-PSMA in Combination With Ipilimumab and Nivolumab for Men With mCRPC - Glivec in Prostate Cancer Patients With Rising PSA Following Radical Prostectomy - Health Gatherings - For Your Health After Cancer - High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy - Low to Moderate Load Power Training for Men With Metastatic Prostate Cancer. ### Drugs in development (9) - Clonidine Phase 3 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Phase 2 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3 - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 3 - [Epinephrine](https://trialight.com/data/asset/epinephrine-bdf4cabf-fe3e-447b-8984-310f4baf125a.md) Phase 3 - Fospropofol Phase 3 - Propofol Phase 3 - Ropivacaine Phase 3 - ST. 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