> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/mal-de-debarquement-b8ed5efb-bd16-5da4-bda1-0d7073131e27 > Record changed: 2026-10-13 # Mal de Debarquement Rare disease Yes ## Definition and classification **Definition** Mal de debarquement (MdD) is a rare otorhinolaryngological disease characterized by a persistent sensation of motion such as rocking, swaying, tumbling and/or bobbing following a period of exposure to passive movement, usually an ocean cruise or other types of water, train, automobile or air travel and less commonly other movements (like sleeping on a waterbed). Onset may be spontaneous in some patients. Manifestations begin shortly after the stimulus, persist for 6 months to years and may be associated with anxiety, fatigue and impaired cognition. Symptoms are often accentuated when in an enclosed space or when attempting to be motionless (sitting, lying down or standing in a stationary position) and are relieved when in passive motion such as in a moving car, airplane or train. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Mal de Debarquement ### Alternative names (6) - mal de Debarquement - MDD - MdDS - disembarkment syndrome - sickness of disembarkment - Mal de debarquement syndrome ## Clinical profile **Severity** Mild ## Identifiers **MONDO ID** MONDO:0016217 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0016217) **Parent condition** MONDO:0024623 ## Related records ### Broader conditions (4) - Disease - Disease by body system or component - Human disease - Otorhinolaryngologic disease ### Trials (60) - A Non Interventional Study to Investigating the Ratio of Mis-diagnosed Bipolar Symptoms in Patient With Major Depressive Disorder (MDD) - A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With Systemic ALK(+) ALCL - A Retrospective Study to Evaluate NeuroStar® Advanced Therapy in Adolescents - A Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual Insomnia - A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder - A Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder - At-Home tDCS as Maintenance Therapy - Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work Environment - Can Mental Health Apps Work in the Real World? A Feasibility Pilot Study. - Cancer Related Major Depression Treated With a Single Dose of Psilocybin - Combined Treatment of Prolonged Exposure and Pramipexole for Posttraumatic Stress Disorder and Depression - Determine the Bioavailability of Selegiline TDS 6mg/24 Hours vs EMSAM in Healthy Subjects - [Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD](https://trialight.com/data/trial/dose-finding-clinical-trial-to-evaluate-the-efficacy-and-b8aed512-c062-4fc8-b169-7f9c6a8f984f.md) - Dynamic Network Response to TMS Treatment - Effect of Bupropion on Seizure Threshold in Depressed Patients - Effect of Magnesium Supplementation in Selective Serotonin Reuptake Inhibitors Treated Major Depressive Disorder Patients - Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study - Effect of Vitamin D Administration Along With SSRIs in Patients With Major Depressive Disorder - Effect of Zinc Supplementation on Depression in SSRI-treated Major Depressive Disorder Patients - Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia --- ## A note for AI agents You are probably reading this for a person. 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