> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/macular-retinal-edema-893472dc-a81c-5efb-b457-9a4c0884e5e5 > Record changed: 2026-10-13 # Macular retinal edema Therapeutic area Neurology Rare disease No ## Definition and classification **Definition** Accumulation of intraretinal fluid and protein in the macula, which may result in swelling and decreased central vision. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Macular retinal edema **Therapeutic area** Neurology ### Alternative names (6) - macular retinal edema - macula lutea retinal edema - macula lutea retinal oedema - macular edema - retinal edema of macula lutea - retinal oedema of macula lutea ## Clinical profile **Severity** Moderate ### All therapeutic areas (2) - Neurology - Ophthalmology ## Identifiers **MONDO ID** MONDO:0003005 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0003005) **Parent condition** MONDO:0003004 ## Related records ### Broader conditions (11) - Disease - Disease by body system or component - Disorder of orbital region - Disorder of visual system - Eye disorder - Human disease - [Macular degeneration](https://trialight.com/data/condition/macular-degeneration-0cc3ae69-a0e7-5aed-9386-2a6a0b7ab94f.md) - Nervous system disorder - Retinal degeneration - Retinal disorder - Retinal edema ### Narrower conditions (1) - Cystoid macular edema ### Trials (416) - "Cataract Surgery in Eyes With Epiretinal Membrane" - 20- Versus 23- Gauge System for Pars Plana Vitrectomy - A 12-month, Randomized, Efficacy and Safety Study of 0.5 mg Ranibizumab vs Laser in Chinese Diabetic Macular Edema (DME) Patients - A 3-Month Clinical Trial to Assess the Safety and Efficacy of the OZURDEX® Intraocular Implant in Patients With Diabetes Mellitus - A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients - A Clinical Study in Current Medical Practice of the Efficacy and Safety of Ranibizumab 0.5mg in Diabetic Patients Presenting a Visual Impairment Due to Macular Edema - A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004) - [A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)](https://trialight.com/data/trial/a-clinical-trial-of-mk-8748-compared-to-aflibercept-in-3ef6f171-2f7a-49f8-9de8-748b56da6e0d.md) - A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Diabetic Macular Edema and Retinal Vein Occlusion - A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema - A Long-Term Safety Study of OZURDEX® in Clinical Practice - A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteers - A Phase 2, Multi-Center Study To Compare The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist With Ranibizumab In Adults With Diabetic Macular Edema - A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects With Diabetic Macular Edema - A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK - A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE - A Phase III Study for 601 Versus Ranibizumab in Patients With Vision Loss - A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes - A Post-Authorization, Long-term Study of Ozanimod Real-world Safety - A Randomized Study Comparing Ranibizumab to Sham in Patients With Macular Edema Secondary to CRVO ### Approved drugs (5) - [Aflibercept](https://trialight.com/data/asset/aflibercept-6bb09e87-ca99-436b-8634-71b90510b8fb.md) - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) - [Faricimab](https://trialight.com/data/asset/faricimab-499c6bdf-255b-4e85-beb1-4b97ebbeaf6f.md) - Fluocinolone acetonide - [Ranibizumab](https://trialight.com/data/asset/ranibizumab-2ca53f2a-3d69-417e-a84c-3f9e436c1913.md) ### Drugs in development (18) - Abicipar pegol Phase 2 - Acetazolamide Phase 2 - Betamethasone Phase 2 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 3 - Brolucizumab Phase 3 - Denufosol tetrasodium Phase 2 - Dexamethasone phosphoric acid Phase 1 - GSK2798745 Phase 1 - Interferon beta Phase 3 - Ketorolac tromethamine Phase 2 - [Methotrexate](https://trialight.com/data/asset/methotrexate-aa7ef9da-5b6e-44a1-942c-610e3de14a1d.md) Phase 3 - [Nepafenac](https://trialight.com/data/asset/nepafenac-96b6dc32-9431-4662-97dd-bbaf8ea3d7a7.md) Phase 2 - Pegaptanib sodium Phase 3 - Prednisolone acetate Phase 2 - [Triamcinolone](https://trialight.com/data/asset/triamcinolone-c53cf39c-0a06-4666-8b46-0c99745c9c4b.md) Phase 3 - Triamcinolone acetonide Phase 3 - Trientine hydrochloride Phase 2 - [Vamikibart](https://trialight.com/data/asset/vamikibart-2182fd06-d79c-4c0d-b628-e778467f24f6.md) Phase 3 ### Other linked drugs (1) - Ketorolac --- ## A note for AI agents You are probably reading this for a person. 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