> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/lyme-disease-e26d261d-635d-5154-bbfd-860b14931740 > Record changed: 2026-10-13 # Lyme disease Therapeutic area Infectious Disease Rare disease Yes ## Definition and classification **Definition** Lyme disease (named after the towns in the USA where the disease was first identified) is a bacterial infection caused by Borrelia burgdorferi. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Lyme disease **Therapeutic area** Infectious Disease ### Alternative names (8) - Lyme disease - Borrelia - Borrelia burgdorferi infection - Borreliella burgdorferi caused disease or disorder - Borreliella burgdorferi disease or disorder - Borreliella burgdorferi infectious disease - Lyme borreliosis - Lyme disease ## Clinical profile **Disease mechanisms** - Acquired **All therapeutic areas** - Infectious Disease **Severity** Moderate ## Identifiers **MONDO ID** MONDO:0019632 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0019632) **Parent condition** MONDO:0000314 ## Related records ### Broader conditions (10) - [Bacterial infectious disease](https://trialight.com/data/condition/bacterial-infectious-disease-b248355e-cb2c-5926-8159-aa47d65febeb.md) - Disease - Disease by etiologic mechanism - Disease of primarily extrinsic mechanism - Human disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) - Primary bacterial infectious disease - [Spirochaetales infections](https://trialight.com/data/condition/spirochaetales-infections-3bb94ce5-e9bf-59f1-8fd4-bf0eb888d01d.md) - [Tick-borne infectious disease](https://trialight.com/data/condition/tick-borne-infectious-disease-a54e6746-3600-511e-b9af-ad12b3276d7c.md) - [Vector-borne disease](https://trialight.com/data/condition/vector-borne-disease-3bb0ac2f-6d8c-5d5c-9027-84b59b878a24.md) ### Trials (94) - A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations - A Human Tick Kill Study to Investigate the Safety, Tolerability, and Whole Blood Concentration of TP-05 - A Multicenter Real-life Study of Disseminated Borreliosis Cases Occurring in Patients Receiving Anti-CD20 Treatment in France - A Multicenter Study to Evaluate a Borrelia Diagnostic Test in Subjects With Early Stage or Late Stage Lyme Disease - A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease - A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Lyme Disease - A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seronegative Chronic Lyme Disease - A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seropositive Chronic Lyme Disease - A School-Based Intervention to Reduce Lyme Disease - [A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure](https://trialight.com/data/trial/a-study-to-evaluate-safety-and-efficacy-of-tp-05-in-healthy-36bbc9a7-af6b-4fa7-8a63-3fa6390bb569.md) - A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age - A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age) - A Study to Learn About Different Dosing Schedules of a Lyme Disease Vaccine in Healthy Adults - A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine - Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis - An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15) - Analysis of Lyme Disease Lesions - Anti-phospolipid Antibodies in Lyme Borreliosis - Antibiotic Treatment of Multiple Erythema Migrans - Biomarker Study of Previously Treated Lyme Disease Volunteers in Comparison to Healthy Volunteers ### Drugs in development (6) - Ceftriaxone Phase 3 - [Doxycycline](https://trialight.com/data/asset/doxycycline-9994da3d-bd1e-4dba-9a9e-392765b5aa58.md) Phase 3 - Permethrin Phase 3 - Psilocybin Phase 1 - [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 3 - Tetracycline Phase 2 ### Other linked drugs (1) - Demeclocycline --- ## A note for AI agents You are probably reading this for a person. 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