> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/lupus-nephritis-2794deed-1735-531d-b3ca-1e5d38aadc8a > Record changed: 2026-10-13 # Lupus nephritis Therapeutic area Nephrology Rare disease No ## Definition and classification **Definition** Glomerulonephritis in the context of systemic lupus erythematosus. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Lupus nephritis **Therapeutic area** Nephrology ### Alternative names (10) - lupus nephritis - SLE nephritis - lupus glomerulonephritis - lupus nephritis - Glomerulonephritides, lupus - Nephritides, lupus - glomerulonephritis, lupus - lupus Glomerulonephritides - lupus Nephritides - nephritis, lupus ## Clinical profile **Disease mechanisms** - Inflammatory **All therapeutic areas** - Nephrology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0005556 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005556) **Parent condition** MONDO:0002462 ## Related records ### Broader conditions (10) - Disease - Disease by body system or component - Disease by developmental or physiological process - Glomerular disorder - Glomerulonephritis - Human disease - Inflammatory disease - [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md) - Nephritis - [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md) ### Trials (326) - A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases - A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus - A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases - A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 - A Multicenter Phase 2a Clinical Study to Evaluate SIM0278 in Subjects With Active Lupus Nephritis - A Pharmacoeconomic Study Comparing the Use of Mycophenolate Mofetil or Cyclophosphamide as Induction Therapy in Lupus Nephritis Patients in Egypt - [A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease](https://trialight.com/data/trial/a-phase-1-study-of-ft819-in-b-cell-mediated-autoimmune-6b8b0d2c-15f0-4af3-a304-bbce1760f628.md) - A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) - [A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease](https://trialight.com/data/trial/a-phase-1-study-of-prulacabtagene-leucel-prula-cel-formerly-0aebce17-d67c-419f-b24a-9fff94392a5e.md) - A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease - A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) - A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G - A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis - A Phase II Study to Evaluate the Efficacy and Safety of SHR-1314 in Lupus Nephritis - A Pilot Study for the Efficacy and Safety of Tacrolimus in the Treatment of Refractory Lupus Nephritis - A Prospective Observational Registry of Patients Treated With LUPKYNIS® (Voclosporin) in the US - A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment - A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease - A Study of ANX009 in Adult Participants With Lupus Nephritis - A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE) ### Approved drugs (2) - Belimumab - Voclosporin ### Drugs in development (55) - [Abatacept](https://trialight.com/data/asset/abatacept-a318efa4-5922-464c-8f45-90c18515f1c5.md) Phase 3 - Abetimus sodium Phase 3 - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 3 - [Anifrolumab](https://trialight.com/data/asset/anifrolumab-4df440fe-efd0-44aa-828f-ea4381468125.md) Phase 3 - [Atacicept](https://trialight.com/data/asset/atacicept-58997791-8042-4d0f-ac69-564cf9e78d1d.md) Phase 3 - Azathioprine Phase 3 - BIIB-023 Phase 2 - Curcumin Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3 - Cyclosporine Phase 3 - [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md) Phase 1 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Phase 2 - Daxdilimab Phase 2 - Dazodalibep Phase 2 - [Deucravacitinib](https://trialight.com/data/asset/deucravacitinib-3033fa9d-d652-4397-81c1-5e76480167af.md) Phase 2 - Diphenhydramine Phase 3 - Diphenhydramine hydrochloride Phase 2 - Efgartigimod alfa Phase 2 - [Etanercept](https://trialight.com/data/asset/etanercept-b317b90d-f8fa-4b94-a6a2-12f14534f4a1.md) Phase 2 - Felzartamab Phase 1 ### Other linked drugs (2) - Abetimus - Tacrolimus --- ## A note for AI agents You are probably reading this for a person. 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