> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7
> Record changed: 2026-10-13

# Liver disorder

Therapeutic area

Endocrinology

Rare disease

No

## Definition and classification

**Definition**

A disease involving the liver.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Liver disorder

**Therapeutic area**

Endocrinology

### Alternative names (10)

- liver disorder
- disease of liver
- disease or disorder of liver
- disorder of liver
- hepatic disease
- hepatic disorder
- liver and intrahepatic bile duct disorder
- liver disease
- liver disease or disorder
- liver disorder

## Clinical profile

**Severity**

Unknown

### All therapeutic areas (2)

- Endocrinology
- Gastroenterology

## Identifiers

**MONDO ID**

MONDO:0005154

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005154)

**Parent condition**

MONDO:0002515

## Related records

### Broader conditions (6)

- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Disease
- Disease by body system or component
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- Hepatobiliary disorder
- Human disease

### Narrower conditions (255)

- Aagenaes syndrome
- Acute hepatitis B virus infection
- Acute hepatitis C virus infection
- Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins
- Acute intermittent porphyria
- Acute liver failure
- Adenocarcinoma of gallbladder and extrahepatic biliary tract
- Adenosquamous bile duct carcinoma
- [Adult hepatocellular carcinoma](https://trialight.com/data/condition/adult-hepatocellular-carcinoma-c10a1a4b-50f0-572a-8bff-bf597d4b7fae.md)
- Aflatoxin-related hepatocellular carcinoma
- Alcoholic fatty liver disease
- Alcoholic hepatitis
- Alcoholic liver cirrhosis
- [Alcoholic liver disease](https://trialight.com/data/condition/alcoholic-liver-disease-76493111-d619-5800-98d4-77d2608dccf0.md)
- Ampulla of vater adenocarcinoma
- Ampulla of vater adenosquamous carcinoma
- Ampulla of vater cancer
- Ampulla of vater clear cell adenocarcinoma
- Ampulla of vater mucinous adenocarcinoma
- Ampulla of vater neoplasm

### Trials (917)

- "CAP" Fetge Gras. Lifestyle Modification Program in Catalonia.
- "Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
- 19 Versus 22-Gauge Needle for EUS-LB
- 3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection
- 30-to-90 Day Challenge: Effects of Alcohol Cessation on Health Outcomes
- 3D Liver Volumetry
- 3D Sonographic Measurement of Volumetric Flow in Transjugular Intrahepatic Porto-Systemic Shunts
- 4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?
- A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers
- A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH
- A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders
- A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)
- A Multi-Center Trial to Study Acute Liver Failure in Adults
- A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH
- A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
- A Pharmacodynamic Study of AV-299 (Formerly SCH 900105) in Subjects With Advanced Solid Tumors Who Have Liver Metastases
- A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment
- A Pharmacokinetic Study of Baricitinib in Participants With Liver Disease
- A Pharmacokinetic Study of CKD-501 in Patients With Impaired Hepatic Function
- A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction

### Approved drugs (8)

- Avatrombopag maleate
- Cholic acid
- Cysteine hydrochloride
- [Entecavir](https://trialight.com/data/asset/entecavir-4df4be16-2f66-48e2-810c-24457b3f43fc.md)
- Gadoxetate disodium
- Givosiran sodium
- Metreleptin
- [Tenofovir disoproxil fumarate](https://trialight.com/data/asset/tenofovir-disoproxil-fumarate-a85e5cf5-74a5-4f7d-a323-e43ff7caf12b.md)

### Drugs in development (264)

- [Abiraterone acetate](https://trialight.com/data/asset/abiraterone-acetate-2c6662c6-31e9-49ed-a022-f76f326fbd3e.md) Phase 1
- Abrocitinib Phase 1
- Adafosbuvir Phase 1
- Ademetionine Phase 3
- [Admilparant](https://trialight.com/data/asset/admilparant-c1bef0e8-811f-4442-9156-e70d2959785c.md) Phase 1
- Afatinib Phase 1
- Aldafermin Phase 1
- Alectinib Phase 1
- Alemtuzumab Phase 2
- Alisporivir Phase 2
- [Alpelisib](https://trialight.com/data/asset/alpelisib-0b0ae0f7-4313-42ef-bbbe-3280ed5ea15c.md) Phase 1
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 2
- [Apalutamide](https://trialight.com/data/asset/apalutamide-146fbb79-89a1-420c-bc35-0403bd284412.md) Phase 1
- Aprocitentan Phase 1
- [Aumolertinib](https://trialight.com/data/asset/aumolertinib-1339ec2f-ba43-4359-aaa7-6a9516518faa.md) Phase 1
- Avacopan Phase 1
- Avatrombopag Phase 3
- Avenciguat Phase 1
- [Balcinrenone](https://trialight.com/data/asset/balcinrenone-039aff61-faf5-4267-bfc5-f89dce767007.md) Phase 1
- Bardoxolone methyl Phase 1

### Other linked drugs (7)

- Acetylcysteine
- Azathioprine
- Dasatinib
- Defibrotide
- Ergocalciferol
- Ferumoxides
- Lactitol

---

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