> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/leiomyoma-f84b9cb4-e902-5ed0-bb93-4d36211170f3 > Record changed: 2026-10-13 # Leiomyoma Therapeutic area Neuromuscular Disease Rare disease No ## Definition and classification **Definition** A well-circumscribed benign smooth muscle neoplasm characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Leiomyoma **Therapeutic area** Neuromuscular Disease ### Alternative names (8) - leiomyoma - fibroid - fibroid neoplasm - fibroid tumor - fibroid tumour - leiomyoma, benign - leiomyomatous neoplasm (morphologic abnormality) - leiomyomatous tumour ## Clinical profile **Severity** Mild ### All therapeutic areas (3) - Neuromuscular Disease - Oncology - Rheumatology ## Identifiers **MONDO ID** MONDO:0001572 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001572) **Parent condition** MONDO:0006106 ## Related records ### Broader conditions (16) - Benign muscle neoplasm - Benign neoplasm - Benign smooth muscle neoplasm - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - Mesenchymal cell neoplasm - Muscle tissue disorder - Musculoskeletal system benign neoplasm - Musculoskeletal system disorder - Myomatous neoplasm - Neoplasm - Neoplastic disease or syndrome - Smooth muscle tumor ### Narrower conditions (51) - Anus leiomyoma - Appendix leiomyoma - Benign metastasizing leiomyoma - Bizarre leiomyoma - Bladder leiomyoma - Breast leiomyoma - Cellular leiomyoma - Central nervous system leiomyoma - Colon leiomyoma - Colorectal leiomyoma - Dartoic leiomyoma - Deep leiomyoma - Disseminated peritoneal leiomyomatosis - Endobronchial leiomyoma - Esophagus leiomyoma - Extrahepatic bile duct leiomyoma - Fallopian tube leiomyoma - Gallbladder leiomyoma - Gastric leiomyoma - Intravenous leiomyomatosis ### Trials (420) - 3 Dimensional Ultrasound in Comparison to Hysteroscopy in Myomas - 3D Ultrasound to Assess in Recurrent Miscarriage - 4K Versus 3D Laparoscopic Colporraphy by Surgeons in Training: a Prospective Randomized Trial - A Clinical Study Evaluating the Relative Bioavailability of SHR7280 Dry Suspension and Tablets - A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia - A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia and Pain - A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery - A Clinical Study to Evaluate Safety of the ExAblate 2100 UF V2 System in the Treatment of Symptomatic Uterine Fibroids - A Long-Term Safety Study of Asoprisnil in the Treatment of Uterine Fibroids. - A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids - A Multicenter Prospective Non-Interventional Study Assessing the Management of Canadian Women With Uterine Fibroids - A Pharmacodynamic Study of Leuprorelin Gelatin-Free Formulation in Female Subjects With Uterine Fibroids. - A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects - A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids - [A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis](https://trialight.com/data/trial/a-phase-3b-study-to-evaluate-bone-mineral-density-with-long-81ab9a0c-cf67-493c-9a01-32b3ca8584b7.md) - A Pilot Study to Determine Optimal Procedure Steps to Obtain and Maintain Uterine Artery Occlusion With the D-UAO Device - A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids - A Prospective Multicenter Non-interventional Study of Women Treated With ESMYA (Ulipristal Acetate) as Pre-operative Treatment of Moderate to Severe Symptoms of Uterine Fibroids - A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) - A Prospective Validation Study of Radiomics in the Differential Diagnosis of Uterine Leiomyoma and Uterine Sarcoma ### Approved drugs (1) - Ulipristal acetate ### Drugs in development (13) - Asoprisnil Phase 3 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3 - Leuprolide Phase 3 - Lidocaine Phase 2 - Linzagolix Phase 3 - Mifepristone Phase 3 - Misoprostol Phase 3 - Onabotulinumtoxina Phase 2 - Ropivacaine Phase 2 - [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 3 - Ulipristal Phase 2 - [Vasopressin](https://trialight.com/data/asset/vasopressin-592303bd-1d7e-43c7-af55-8c1dcb6024f0.md) Phase 2 - Vilaprisan Phase 3 ### Other linked drugs (5) - [Estradiol](https://trialight.com/data/asset/estradiol-0b121e99-a1da-433f-be00-a9b7e9d5f80c.md) - Linzagolix choline - Norethindrone acetate - [Oxytocin](https://trialight.com/data/asset/oxytocin-787cf970-fce1-4bab-b1c9-6d816e9784fb.md) - [Relugolix](https://trialight.com/data/asset/relugolix-b0e3fb81-fd33-4257-84d9-45f04bcadfc2.md) --- ## A note for AI agents You are probably reading this for a person. 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