> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/large-b-cell-lymphoma-f5bcdccf-5fc1-56d0-93c4-bc395fc1bab9 > Record changed: 2026-10-13 # Large B-cell lymphoma Therapeutic area Hematology Rare disease No ## Definition and classification **Definition** A B-cell lymphoma that is characterized by large lymphoid cells of the B-cell lineage that by definition form sheets or clusters. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Large B-cell lymphoma **Alternative names** - large B-cell lymphoma **Therapeutic area** Hematology ## Clinical profile **Severity** Severe ### All therapeutic areas (3) - Hematology - Immunology - Oncology ## Identifiers **MONDO ID** MONDO:0968974 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0968974) **Parent condition** MONDO:0004095 ## Related records ### Broader conditions (16) - [B-cell neoplasm](https://trialight.com/data/condition/b-cell-neoplasm-ffd0710d-7dbd-55bc-a4a5-3c1cf532bac2.md) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Hematologic disorder - [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) - [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md) - Human disease - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Leukocyte disorder - Lymphoid hemopathy - Lymphoid neoplasm - [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) - Neoplasm - Neoplastic disease or syndrome ### Trials (103) - 89Zr-DFO-REGN3767 in PET Scans in People With Diffuse Large B Cell Lymphoma (DLBCL) - A Phase 2 Study of Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma - A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies - A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma - A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy - A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies - A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma - A Study of Automated Axicabtagene Ciloleucel for R/R Large B-cell Lymphoma. - [A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies](https://trialight.com/data/trial/a-study-of-azd0486-monotherapy-or-in-combination-with-other-46d632fc-c1a6-4f86-bce7-6e88deec222b.md) - A Study of C-CAR039 (Prizloncabtagene Autoleucel) in Patients With Relapsed/Refractory Large B-Cell Lymphoma - A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL - A Study to Evaluate Zanubrutinib and Tislelizumab in Progressive Lymphoma Post CAR-T - A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy - A Trial of Polatuzumab Vedotin, Obinutuzumab and Glofitamab As a Peri-CAR-T Cell Treatment Strategy in Large B-cell Lymphoma - Acalabrutinib in Combination With R-miniCHOP in Older Adults With Untreated Diffuse Large B-Cell Lymphoma - AI-Driven Treatment Strategy vs Pola-R-CHP in Untreated LBCL - AI-Driven Treatment Strategy vs ZR2 in Older Treatment-naive Patients With LBCL - [An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma](https://trialight.com/data/trial/an-open-label-study-comparing-glofitamab-and-polatuzumab-f156f2c9-5ed9-4722-bee5-2c3dd06890d3.md) - An Open-Label, Single Center Phase 2 Study of Magrolimab, Rituximab and Radiation as Bridging Strategy Before CAR T-Cell Therapy in Patients With Relapsed or Refractory Large B-cell Lymphoma - Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies --- ## A note for AI agents You are probably reading this for a person. 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