> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/kidney-failure-f26737b4-3a55-50be-b6c3-b76514cb5067 > Record changed: 2026-10-13 # Kidney failure Therapeutic area Nephrology Rare disease No ## Definition and classification **Definition** An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Kidney failure **Therapeutic area** Nephrology ### Alternative names (5) - kidney failure - failure, renal - renal failure - renal failure syndrome - renal insufficiency ## Clinical profile **All therapeutic areas** - Nephrology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0001106 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001106) **Parent condition** MONDO:0005240 ## Related records ### Broader conditions (5) - Disease - Disease by body system or component - Human disease - [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md) - [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md) ### Narrower conditions (5) - Acute kidney injury - Acute kidney tubular necrosis - [Chronic renal failure syndrome](https://trialight.com/data/condition/chronic-renal-failure-syndrome-5b98a1aa-2089-59e6-af27-bff008ad07ac.md) - Uremia - Uremic neuropathy ### Trials (4,266) - "Hypoxic vs. Aerobic Training in Chronic Kidney Disease - "Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction" - "Residual Kidney Function and Oxidative Stress in Incremental vs Standard Peritoneal Dialysis (2 Mexican Centers)" - (TIMP-2)x(IGFPB7) to Predict Acute Kidney Injury (AKI) in Aortic Surgery - 1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy - 12 Weeks of Hemodialysis With Medium Cut-Off Filter Compared to Hemodiafiltration With Standard High-flux Filter. - 15141 Fixed Dose Correction / naïve and Pre Dialysis (Europe and Asia Pacific) - 16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis - 20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia - 20070360 Incident Dialysis - 24 Hour Use of the Wearable Artificial Kidney - 24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease - 2D-speckle Tracking in Pediatric Renal Chronic Disease - 4 Week Correction Study in Subjects With Anemia Associated With Chronic Kidney Disease Who Are Not Undergoing Dialysis - 4 Week Switch Study in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease - 4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis - 42-Day Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia - 8-week Pilot Study of Relaxation for Weight Loss in Adults With Chronic Kidney Disease - A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis - A Bioequivalence and Efficacy Study of MB-102 (Relmapirazin) in Chinese Participants ### Approved drugs (7) - Benazepril hydrochloride - Calcium acetate - Captopril - Dopamine hydrochloride - Metoclopramide hydrochloride - Quinapril hydrochloride - Terlipressin ### Drugs in development (103) - [Abiraterone acetate](https://trialight.com/data/asset/abiraterone-acetate-2c6662c6-31e9-49ed-a022-f76f326fbd3e.md) Phase 1 - Acetylcysteine Phase 1 - Adafosbuvir Phase 1 - Afatinib Phase 1 - Alefacept Phase 1 - Alemtuzumab Phase 1 - Alfacalcidol Phase 2 - Amino acids Phase 2 - [Apixaban](https://trialight.com/data/asset/apixaban-9e91f03a-6eac-4da8-9f08-88d740399be5.md) Phase 3 - Articaine Early phase 1 - Atorvastatin Phase 3 - Avadomide Phase 1 - Avibactam Phase 1 - Aztreonam Phase 1 - Bemiparin Phase 1 - Bersacapavir Phase 1 - Bicarbonate Phase 3 - Canagliflozin Phase 1 - Certoparin Phase 1 - [Citric acid](https://trialight.com/data/asset/citric-acid-25b001b8-fd7a-438c-85e8-81f14a72a65a.md) Phase 3 ### Other linked drugs (5) - Ilepatril - Mannitol - Sodium thiosulfate - Tacrolimus - [Voriconazole](https://trialight.com/data/asset/voriconazole-1d4648d7-4d92-4ae6-9eee-00ae8c143268.md) --- ## A note for AI agents You are probably reading this for a person. 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