> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/kennedy-disease-6e5ffe98-b578-528f-8d1e-9840aeb87f49 > Record changed: 2026-11-04 # Kennedy disease Therapeutic area Neurology Rare disease Yes ## Definition and classification **Definition** Kennedy's disease, also known as bulbospinal muscular atrophy (BSMA), is a rare X-linked recessive motor neuron disease characterized by proximal and bulbar muscle wasting. **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Kennedy disease **Therapeutic area** Neurology ### Alternative names (11) - Kennedy disease - Kennedy's disease - SBMA - SMAX1 - spinal and bulbar muscular atrophy of Kennedy, X-linked recessive - spinal and bulbar muscular atrophy, X-linked type 1 - X-linked BSMA - X-linked bulbospinal amyotrophy - X-linked bulbospinal muscular atrophy - X-linked spinal and bulbar muscular atrophy - spinal and bulbar muscular atrophy, X-linked 1 ## Clinical profile **All therapeutic areas** - Neurology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0010735) **Severity** Severe ### Disease mechanisms (2) - Genetic - Hereditary Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0010735) ## Identifiers **MONDO ID** MONDO:0010735 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0010735) **Parent condition** MONDO:0024237 ## Related records ### Broader conditions (11) - [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - [Hereditary disease](https://trialight.com/data/condition/hereditary-disease-df2f8f05-e0c9-5777-8e51-c3b6639743d3.md) - Hereditary neurological disease - Human disease - Inherited neurodegenerative disorder - [Nervous system disorder](https://trialight.com/data/condition/nervous-system-disorder-541eb3ed-9656-574d-babf-28139b060a42.md) - [Neurodegenerative disease](https://trialight.com/data/condition/neurodegenerative-disease-aafbeed5-19eb-5b92-ae0b-73cbafb719c7.md) ### Trials (58) - A Phase 1a/1b Study to Evaluate the Safety of EZN-4176, in Adult Patients With Castration-Resistant Prostate Cancer - A Placebo-controlled Study of Clenbuterol in Spinal and Bulbar Muscular Atrophy - A Safety Study of JNJ-56021927 in Participants With Metastatic Castration-Resistant Prostate Cancer - A Study of AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer - A Study of AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer - A Study of NIDO-361 in Patients With SBMA - [A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer](https://trialight.com/data/trial/a-study-to-compare-the-efficacy-and-safety-of-bms-986365-ed92a659-d708-48f9-ac4d-f881bc9a96fe.md) - A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Of AJ201 In Patients - A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1) - A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs - Acoustic and Perceptual Markers of Dysarthria in Amyotrophic Lateral Sclerosis (ALS) - ALS/MND Natural History Study Data Repository - An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer Participants - An Open Label Prostate Cancer Study in Japanese Patients - Androgen Deprivation Therapy in Advanced Salivary Gland Cancer - Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity - Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer - AR, IGF-IR, IR and Peripheral Artery Disease - Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia - Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer ### Drugs in development (5) - Clenbuterol Phase 2 - Dutasteride Phase 2 - Leuprolide acetate Phase 2 - Mexiletine hydrochloride Phase 2 - Testosterone enanthate Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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