> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/iron-metabolism-disease-60cdd335-b242-5ff2-9454-d64a2750e8f9
> Record changed: 2026-11-04

# Iron metabolism disease

Therapeutic area

Metabolic Disease

Rare disease

No

## Definition and classification

**Definition**

Disorders in the processing of iron in the body: its absorption, transport, storage, and utilization.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Iron metabolism disease

**Therapeutic area**

Metabolic Disease

### Alternative names (8)

- iron metabolism disease
- disorder of iron metabolism
- Iron Metabolism Disorders
- disorder, iron metabolism
- disorders, iron metabolism
- iron metabolism disorder
- metabolism disorder, iron
- metabolism disorders, iron

## Clinical profile

**All therapeutic areas**

- Metabolic Disease

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002279)

**Severity**

Moderate

## Identifiers

**MONDO ID**

MONDO:0002279

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002279)

**Parent condition**

MONDO:0000226

## Related records

### Broader conditions (5)

- Disease
- Disease by developmental or physiological process
- Human disease
- [Metabolic disease](https://trialight.com/data/condition/metabolic-disease-3d73c19d-b8c8-5be8-add5-77c7d794dacd.md)
- Mineral metabolism disease

### Narrower conditions (37)

- Aceruloplasminemia
- African iron overload
- Atypical pantothenate kinase-associated neurodegeneration
- Autosomal recessive Parkinson disease 14
- Classic pantothenate kinase-associated neurodegeneration
- Digenic hemochromatosis
- Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome
- Fatty acid hydroxylase-associated neurodegeneration
- Hemochromatosis type 1
- Hemochromatosis type 2
- Hemochromatosis type 2A
- Hemochromatosis type 2B
- Hemochromatosis type 3
- Hemochromatosis type 4
- Hemochromatosis type 5
- Hemosiderosis
- Hemosiderosis, pulmonary, with deficiency of gamma-a globulin
- Hereditary hemochromatosis
- Kufor-Rakeb syndrome
- Lane Hamilton syndrome

### Trials (669)

- .Patient Blood Management Program in Liver Transplantation
- "Iron Overload and Endocrinological Diseases"
- A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.
- A Clinical Study on Adherence and Efficacy of Different Doses of Active Iron in Treatment Resistant Subjects
- A Clinical Trial Assessing the Efficacy of Intravenous Iron for the Treatment of Anemia Following Cardiac Surgery
- A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis.
- A Novel Iron-Based Supplement for Athletes Aged 14-17
- A Novel Iron-Based Supplement for Athletes Aged 18-25: Phase II
- A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
- A Pilot Study Comparing Tolerance of Oral Heme Iron Polypeptide With Oral Ionic Iron
- A Pilot Study to Assess the Influence of Dietary Organic Acids on Iron Absorption.
- A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females
- A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity
- A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women
- A Randomized, Double-blind, Comparative Study of Intravenous Iron Isomaltoside 1000 (Monofer®) Against Placebo
- A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
- A Retrospective Analysis of Neevo®/Neevo®DHA Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
- A Study Assessing Iron Status and Anemia in Filipino School Children From MIMAROPA Region
- A Study of Intravenous Iron Isomaltoside 1000 (Monofer®) Administered by Infusions to Iron-deficient Blood Donors
- A Study to Collect Data to Build Artificial Intelligence Derived Algorithms for Estimating Iron Status of Children

### Drugs in development (2)

- Vamifeport Phase 1
- Vamifeport hydrochloride Phase 1

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